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DOB vs DOI?

DOI is likely safer and less toxic in terms of peripheral vasoconstrictive side effects--while it is a high-efficacy partial agonist at the 5-HT2A/B/C receptors (~70% of the response caused by 5-HT), DOB is an absolute full agonist (>100% of 5-HT response). For reference, ergoloids like LSD are around 40% in their agonist efficacy, as are tryptamines like psilocin/miprocin. Remember that agonist efficacy is different than agonist affinity, which is only a measurement of how tightly a given chemical sticks to a receptor, not how much it activates the receptor in comparison with the endogenous ligand. Obviously, DOI, DOB and LSD are all very high affinity 5-HT2A/C receptor agonists. Dose-wise, DOB is ever slightly more potent than DOI.

In terms of duration, however, DOI and DOB should be virtually identical. Given the choice, I'd take DOI every single time. In theory, DOC is supposed to be a little friendlier than DOI, which is friendlier than DOB. However, given a broader choice, I'd take neither and opt for the ergoloid. The 2,5-dimethoxy-4-halo-phenethylamine psychedelics cause way too much (that is, too long-lasting) tolerance for my enjoyment these days. Tolerance to the effects of something like LSD can be dissipated in around 7 days, 14 being optimal. Tolerance to DOI takes around a month to fully reset. Curiously, even though compounds like DMT and 5-MeO-DMT are also full agonists at the 5-HT2A/C receptors, tolerance to their effects resets after as little as 24 hours. Phenethylamines must cause a more profound downregulation of 5-HT2A receptors than tryptamines or ergoloids.

Some of those DOX compounds are really esoteric--I'd be interested in trying them maybe once, just for novelty's sake. I mean how often would someone encounter something like DOET or DOEF.
 
hey dudes im from adelaide, SA. got hooked up with trips aaaaages ago, they were multicoloured rainbow tabs and defs DOI or sumthin, we were informed its just lsd but yeh 12 hours later when expecting to come down.... came up! and was tripping for a good solid 2 days of intense visuals and exhausting daunting head fuckery haha

anyone got info on these particular tabs? coz it was easily the most intense time of my life times 20 haha.

the tabs look like swirly rainbow and must join into a big picture instead of individual pics on each stamp.

cheers
 
I would not take DOI or DOB, they both suck IMO.

I always get mild psychosis after both, they last too long and cause too much of a dirty feeling.

If you trip though, take it with friends.

DOx is not like LSD, it's not a drug you want to take alone. It's best to trip with people on these amphetamine type psychedelics. You'll laugh a lot for sure.
 
The only similarity between DOB and 2C-B I found was what they did to colors. They got metallic and soft/pastel at the same time and somewhat intensified. But with 2C-B for me there was also increased appreciation, for DOB not at all.
Never tried DOI...
 
Ronald said:
P.S. if you dont want to go in for a drug as brutally potent and dominant as DOB, DON is the 'black & white' version of DOB. DOI is DOB's demented brother. Choose whichever you prefer, I would still say a CLEAN dose of DOB in the morning is your best bet. Really make sure it is analytically pure though. Dont worry 2 much about wasting product when it is of this order of potency.
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Yep....I obviously don't know if you have access to DON but it is one of my all time favorite compounds. 4 mg is a nice start, duration ~15 h. It is too bad there is so little public information about this compound other than a couple of trip reports at Erowid AFAIK. :)
 
As for meth similarities I've probably only used meth in dirty rolls, but it does have an amphetamine component at the start and at the end. It also generally makes me nasty about a day after it wears off. I've done a lot of all the DOx's except for DOM which I hear is the best of them. If you don't like 2C-B I'd imagine DOB would be a really unfun time. I've spent more time on DOB with overall anxiety, hyper-alertness, a very discontent stomach, an almost complete inability to talk confidently, and this general laziness than with any other drug. Also the amphetamine nature of it scares me a little bit. I spent about 6 months once upon a time with a lot of DOC and DOI and I've never been the same since. 2C-B is like being tickled by friendly angels compared to DOB's molested by smelly bikers. I find DOI to be much more pleasurable than DOB. It's a little more analytical, but less body effects. DOC is my favorite out of the bunch. Its like happy speed with weird electrical body buzzes. I think all the DOx's I've experienced are not worth it however.

I know that where I live there were "rainbows" or "tie-dyes" floating around that were DOI. I did the classic, "This isn't doing anything." And munched two more thought, "I'll eat another half for good measure." I found it years ago on Erowid, but this is the exact image of what it was. Not that it means anything because you're half a world away, but this is what I had pleasure/misfortune of experiencing:

http://www.erowid.org/chemicals/show_image.php?i=lsd/lsd_blotter_ap_kaleidoscope-2000.jpg

Peace,
PL
 
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I think all the DOx's I've experienced are not worth it however.
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Same here. As a matter of fact DOx's have done more harm for my mental status than any other drug I've ever tried.

I think DXM is much more safe than DOx, so is alcohol.

DOX is too sketchy, I wish people would stop making it and distributing it as LSD. It's so goddamn annoying to buy LSD and get DOx. I've gotten DOx from trusted dealers too who had good intentions on distributing "acid" to spread the love. People are especially fooled when they get DOC, since it's ALOT like LSD but not quite. It can fool people.

Some would say I'm lucky to be able to get DOx, I disagree. I wish I was getting bunk LSD that didn't do ANYTHING instead of give me a trip that I don't want.

If you can even call DOx a trip...lol.

Not even DOM, the best DOX is really a trip. It's more like MDMA-like/speedy effects with visuals and cognitive changes. People seem to think visuals mean it's a trip.....

To me a trip is something deeper, obviously LSD and mushrooms are trips...no question about it.
 
They're both shit awful, I threw out half grams of both of them.
 
Not even DOM, the best DOX is really a trip.
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Personally I've found DOM to be a very useful compound (up there with LSD IMO), but the 4 -halogen amphetamines are rather nasty. 4-Alkyl groups ( methyl, ethyl) seem to make quite acceptable psychedelics, unfortunately I can't say the same for the 4-halogen series (but that''s my personal opinion - some people actually like DOC/DOB, but not me)
 
I remember about 4 years ago, when I was first experimenting with LSD, a guy I knew said he got some "new" drug and sold me two 4mm x 4mm blotters of the substance. He said that his dude had taken two and was experiencing "walls breathing" and all that typical shit. I was dubious about his claim that it was a "new" drug, but took them anyway. About 3 hours later, I wasn't feeling much of anything, except possibly a SLIGHT speedy feeling, similar to a low dose of dextro-amphetamine (Adderall). I had never experienced a drug with such a long and evasive come-up, so I assumed that the blotters were bunk, or perhaps really weak. I told this to my dude, and he apologized and gave me 3 more for free. I took these, and within about 2-3 more hours (not sure of the exact time period, for this was 4 years ago), I was feeling "strange" and was most prominently speeding. I attained very subtle and understated visuals (compared to those of LSD or mushrooms), but they were constant throughout. The most prominent qualities to this trip were the feelings of speeding and a somewhat euphoric feeling similar to a low dose of MDMA. These effects lasted around 14 hours, with a comedown after that lasting about 10. I'm still not sure what this chemical was, though at the time I looked it up and assumed it to be either DOB or DOI, judging by the strong amphetamine-type quality and long lifespan of the trip. Can anyone offer their opinion as to what this was?
 
Haha yeah sorry.. I just caught onto that after reading another closed thread where someone did the same thing. Again, sorry about that!
 
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