Jabberwocky
Frumious Bandersnatch
There was a paper published in the journal Science that suggested there are indeed ars arsenic-based life forms in the sense that they built their DNA using arsenic. I remember reading that paper and thinking wow.
That story turned out to have some faulty conclusions in it, though the organisms showed a remarkable ability to work with arsenic compounds selectively. Not to mention organoarsenic compounds are known and used by life.
http://www.nature.com/news/arsenic-life-bacterium-prefers-phosphorus-after-all-1.11520
Just want to point that out because the lake mono study has some controversy behind it. It has lead to some really interesting science though.
As for silicon-based life (if I can speculate a bit) what I've seen about silicon chemistry is it is remarkably rich, more so than carbon based chemistry under conditions we associate with life (aqueous environments and room temperature). Of course carbon based chemistry has been studied a lot more, so maybe that is merely the impression one gets. The chemistry of silicates in aqueous environments is basically a wide open frontier in science because of the polymerization and complicate polyanion structures that form. I studied this stuff in the literature for a time because I worked with silicon etching reactions. I didn't get very far because the chemistry is so complicated and there are so many types of players in solution that you can't really tease out any workable hypothesis. The people that study this stuff talk in generalities and statistics, not refined chemical pathways like organic chemists. Basically, you can't even give a concise answer to the question: "what is the etching byproduct of crystalline silicon in aqueous alkaline solution"
so if aqueous, silicon-based life were feasible, I'm inclined to say it would require even more selectivity and control than carbon-based life. Silicon-based chemistry certainly seems rich enough to satisfy the complexity required for life. The fundamental building blocks of this life might gain an advantage as far as the versatility of its components (ex like an enzyme that catalyzes multiple chemical reactions). Complexity would have to be higher.
Edit:B_D beat me to it
That story turned out to have some faulty conclusions in it, though the organisms showed a remarkable ability to work with arsenic compounds selectively. Not to mention organoarsenic compounds are known and used by life.
http://www.nature.com/news/arsenic-life-bacterium-prefers-phosphorus-after-all-1.11520
Just want to point that out because the lake mono study has some controversy behind it. It has lead to some really interesting science though.
As for silicon-based life (if I can speculate a bit) what I've seen about silicon chemistry is it is remarkably rich, more so than carbon based chemistry under conditions we associate with life (aqueous environments and room temperature). Of course carbon based chemistry has been studied a lot more, so maybe that is merely the impression one gets. The chemistry of silicates in aqueous environments is basically a wide open frontier in science because of the polymerization and complicate polyanion structures that form. I studied this stuff in the literature for a time because I worked with silicon etching reactions. I didn't get very far because the chemistry is so complicated and there are so many types of players in solution that you can't really tease out any workable hypothesis. The people that study this stuff talk in generalities and statistics, not refined chemical pathways like organic chemists. Basically, you can't even give a concise answer to the question: "what is the etching byproduct of crystalline silicon in aqueous alkaline solution"
so if aqueous, silicon-based life were feasible, I'm inclined to say it would require even more selectivity and control than carbon-based life. Silicon-based chemistry certainly seems rich enough to satisfy the complexity required for life. The fundamental building blocks of this life might gain an advantage as far as the versatility of its components (ex like an enzyme that catalyzes multiple chemical reactions). Complexity would have to be higher.
Edit:B_D beat me to it