First of all, how old are you? That's a major factor in determining your susceptibility to developing the condition. One thing about mental illness, you either have it or you don't. That is to say, it's mostly hereditary. Schizophrenia is associated with neurological serotonin dysfunction.
Individuals who are predisposed to developing this illness will show signs of personality disorders through out their entire adolescence, with the full blown condition finally erupting between the ages of 16 and 25 (mostly).
If you are concerned about fucking yourself up with psychedelics (which is a totally serious concern), you should consider the following:
1. Is there a history of mental illness in your family?
2. Do you have any psychiatric condition/are you generally a stable person?
If the answer to those two questions is yes, steer clear of any drug use. Sorry, but the gain is just not worth the risk.
It is true that if you have the genetics for schizophrenia, it's going to show up anyway. But there's a whole world of difference between slowly learning how to live with the condition, or getting it flat on your face. That's up to you.
However, if there's nothing to point out you might have it, there is very little chance (and I say this cautiously) that you will ever develop any condition at all. If you don't have any specific pointer to that, you should figure it out before you do any kind of experimentation. One thing to consider is, how well does your mind react to lighter substances i.e cannabis? Do you often get paranoid or scared when smoking? The idea being that if cannabis gives you a hard time, psychedelics can do that 100x.
The key to having a good time on psychedelics is set and setting (kind of a cliché but nonetheless crucial). Start with small doses and wait an hour or so before redosing. Always ask yourself, "Is this where I want to be? Is this level comfortable enough for me?". As you gain experience you will learn how to work the stuff better.
I don't know weather you have any experience at all, but your first time is much like losing your virginity. If it goes about well, you know you're built for this. If the experience turns out to be a train wreck, you need to follow back on your footsteps and understand what went wrong. Eventually if you act responsibly, you can almost assure yourself a good time.