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Benzos Diazepam dependence?

Ohhhh okay man. I assumed it was all benzo use, not opiates being part of the 3-4 times a week.

I'm super tired man, but I will revisit this thread in the morning and give you a better taper plan.

gooodnighttho peaceee
 
regularly nearing 150mg/day towards the end

150mg of alprazolam a day?! Holy shit. Did I read that right?

That must have been an unbelievably long road of recovery to travel down. I'm amazed that you made it back, but it's good to know that it can be done.
 
Is anyone here able to actually say that they have had withdrawals from these kind of quantities? So far I have heard no actual solid personal evidence apart from people who were taking 100x or so more than me. Mainly just lots of scare stories, with no evidence to back it up. While I am all for damage limitation, and encouraging sensible behaviour, people should be aware that if they go too far with this kind of thing they risk beginning to sound like "Talk to Frank" (UK) or "Just say NO"...

If you wildly exaggerate the risks, then people won't believe you.

Now, take Anon 54's post above. He was pretty much shouted down, although he is one of the very few people to have actually given personal testimony. One person even accused him of having a clouded mind from taking too many drugs, which I think is particularly low on these boards. Now, admittedly his grammar/spelling etc. is awful, but perhaps English is not his first language? Anyway, I feel as though someone should stick up for him, so I will answer the points raised by the subsequent poster myself:

1. "nothing will happen if u quit cold turkey. Id say the chance of having a seizure would be less than 1%."

This seems perfectly reasonable advice to me. For example, Prof Ashton herself says:

"People who have become dependent on therapeutic doses of benzodiazepines usually have several of the following characteristics.

1.They have taken benzodiazepines in prescribed "therapeutic" (usually low) doses for months or years.

2.They have gradually become to "need" benzodiazepines to carry out normal, day-to-day activities.

3.They have continued to take benzodiazepines although the original indication for prescription has disappeared.

4.They have difficulty in stopping the drug, or reducing dosage, because of withdrawal symptoms.

5.If on short-acting benzodiazepines (Table 1) they develop anxiety symptoms between doses, or get craving for the next dose."

...the list goes on for some length, and the only one I personally fit is number 1 (technically I don't even fit this as I don't use them "therapeutically", ie. every day).

And here are a couple of quotes from medical literature on the subject (easily found on google scholar):

"Instances are also reported within the high-dosage category of more serious developments such as seizures and psychotic reactions."

"The seizures were not considered to be a toxic effect of flumazenil, but many of them probably were due to an unmasking of the anticonvulsant effect of the previously used benzodiazepine or to a severe benzodiazepine-withdrawal syndrome"

etc. etc. Especially note: "high-dosage category" and "severe benzodiazepine-withdrawal syndrome". From everything I have read, I would say that it is highly likely that the chance of me suffering seizures at my usage levels is less than 1%. If you have personal evidence to the contrary, please tell me about it!

2. "valium is one that is was easy for me to quit. alot easier than than caffeine or cigarettes."

What is your problem with this? Are you accusing him of lying? Why would he lie about this?

3. If ya using more than 400mg of diaz a day for a few months than ya in trouble. but at least it valium.

Again I don't see the problem...this may be irrelevant to my personal case, but I believe he was giving an example of a situation in which you might expect to suffer severe withdrawals.

4. valium, temazepam, & valium.

Surely a simple typo? Does this really deserve to be highlighted?

5. its VERY ADDICTED but it's also VERY HARD TO GET ADDICTED TOO.

Ignoring the poor English, this is indisputably true. Unlike, say, opiates, it takes a while to get addicted to benzos. But as with, say, alcohol or GHB, the withdrawals can be much more severe.

Now, to the person who said "let's just say you get lucky and don't get a seizure, which is definitely a possibility. You will still go through mental hell"...here is some maths:

Let us suppose, for the sake of argument, that I have a very high "personal diazepam half-life". of, say, 84 hours, or 3.5 days (if we assume a lower half-life, which is likely, then everything I am about to say is more true). Then I can expect my blood levels of diazepam to halve twice per week. If I was taking 40mg a week, then I would stabilise on, roughly, a blood-level of 15mg diazepam. Now suppose I stop. Then within 4 days my blood levels of the drug will be less than 7mg. As I have done this many times and not felt any withdrawals whatsoever, we can safely assume that I am physiologically addicted to no more than a constant blood-level of 5mg. This is equivalent to taking less than 1.5mg diazepam per day (which itself is equivalent to less than 0.075mg xanax). Is it really a FACT that I will go through mental hell from quitting these levels?

I am honestly not trying to be a "tough guy". I simply want to know if I'm physically addicted or not. I don't plan to stop using valium completely, merely cut it down to levels at which I am not at risk of addiction.

Please...as much as I appreciate the concern, don't give scare stories just because you have had a severe benzo habit in the past and suffered for it. I'm looking for answers from people who have had small habits and quit.
 
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Ahhhhhh. I am livid. I just typed out a lengthy response, accidentally hit the back button and now have to start over..... It keeps saying autosaved but now I know that's not true.

1) You are not qualified to assess your seizure risk, based on things you've read online, the only people even remotely qualified to assess it would be those members of this board holding a degree in medicine. This is a harm reduction forum and sometimes HR means referring posters like yourself towards the care of a medical professional, especially when the consequences are possible, no matter how remote this possibility may seem to you.

2) I bolded statements I didnt understand or disagreed with, I never accused anyone of lying.

3) The statement was highlighted for the "at least its valium" part. Do you think if a person asked their doctor for help getting off benzodiazepines, he'd say "Oh, well it appears you're only on valium". It doesn't matter if you're coming off a hardcore short acting potent benzo like Triazolam (Halcion) or a long acting one like diazepam (Valium), there is imminent risk of seizures. The doctor would lose his license to practice medicine, and would lose even more if anything happened to you, God forbid.

4) I did not bold typos, I did not understand what he's saying.

5) Benzodiazepines and Opiates, Apples and Oranges. Do you honestly believe that "it's harder to get addicted to benzodiazepines" is indisputably true? I find it questionable that you dismiss my 9 years of benzodiazepine therapy. It's not like I was on triple digit dosing from day one, a lot of things happen in a decade, I experienced varying degrees of addiction and have experience coming off low doses just as I do coming off high doses. No one's trying to "Scare" you, we are trying to get you to grasp the gravity of the situation.

The plan you suggested in step 5 would take a toll on you psychologically, I can't say if it will be mental hell, so to speak, as everyone is different, but you will be uncomfortable, at the very least. You ought to try doing a proper taper. I can't justify cold turkey detox for someone in your position, so if you're looking for responses like "Oh yeah just quit cold turkey", I think Anon54's post will be the only one you find.
 
i hope i dont get in trouble for saying this but by the sounds of ya habit nothing will happen if u quit cold turkey. Id say the chance of having a seizure would be less than 1%. U have may get rebound anxiety but I dont think so
that just IMHO im sorry if anyone disagrees but ive been hooked to benzos before & valium is one that is was easy for me to quit. alot easier than than caffeine or cigarettes.
but u may as well taper anyway. better safe than sorry. u have the supply just taper anyway to atleast get rid of an re-bound anxiety which i rekon u may have a a fair chance of getting

Ive abused benzos for yrs. valium has never given me rebound anxiety. defensively not even close to a seizure. the only benzos that has given me a "taste of w/d was when I abused xanax for a while & just stopped. I was a little anxious. nothing as bad as a night out drinking though.

but I DO GET what benzo w/d can potentially be. If ya using more than 400mg of diaz a day for a few months than ya in trouble. but atleast it valium.
if ya using more than 20mg of Xanax for a few months well.... ud be dead if u didnt go to the ER.. well probably. lets make it 40mg. than u wouldnt make it if u just quit

Ive been a user of valium, temazepam, & valium. last dose of valium was 200mg the other day with GFJ & subutex. Ive had valium with alot of alcohol oxy & meth too. Dont drink with benzos. for some reason i actually get less drunk but its probably cuz im a little calmer & drink slower but everyones different. ive heard it can put some ppl in a coma
its VERY ADDICTED but it's also VERY HARD TO GET ADDICTED TOO.
so ive been using benzos for a few yrs. never a problem with w/d. but i someimtes go weeks without taking em

Nobody listen to this bullshit, especially the OP.
 
Is anyone here able to actually say that they have had withdrawals from these kind of quantities? So far I have heard no actual solid personal evidence apart from people who were taking 100x or so more than me. Mainly just lots of scare stories, with no evidence to back it up. While I am all for damage limitation, and encouraging sensible behaviour, people should be aware that if they go too far with this kind of thing they risk beginning to sound like "Talk to Frank" (UK) or "Just say NO"...

If you wildly exaggerate the risks, then people won't believe you.

Now, take Anon 54's post above. He was pretty much shouted down, although he is one of the very few people to have actually given personal testimony. One person even accused him of having a clouded mind from taking too many drugs, which I think is particularly low on these boards. Now, admittedly his grammar/spelling etc. is awful, but perhaps English is not his first language? Anyway, I feel as though someone should stick up for him, so I will answer the points raised by the subsequent poster myself:

1. "nothing will happen if u quit cold turkey. Id say the chance of having a seizure would be less than 1%."

This seems perfectly reasonable advice to me. For example, Prof Ashton herself says:

"People who have become dependent on therapeutic doses of benzodiazepines usually have several of the following characteristics.

1.They have taken benzodiazepines in prescribed "therapeutic" (usually low) doses for months or years.

2.They have gradually become to "need" benzodiazepines to carry out normal, day-to-day activities.

3.They have continued to take benzodiazepines although the original indication for prescription has disappeared.

4.They have difficulty in stopping the drug, or reducing dosage, because of withdrawal symptoms.

5.If on short-acting benzodiazepines (Table 1) they develop anxiety symptoms between doses, or get craving for the next dose."

...the list goes on for some length, and the only one I personally fit is number 1 (technically I don't even fit this as I don't use them "therapeutically", ie. every day).

And here are a couple of quotes from medical literature on the subject (easily found on google scholar):

"Instances are also reported within the high-dosage category of more serious developments such as seizures and psychotic reactions."

"The seizures were not considered to be a toxic effect of flumazenil, but many of them probably were due to an unmasking of the anticonvulsant effect of the previously used benzodiazepine or to a severe benzodiazepine-withdrawal syndrome"

etc. etc. Especially note: "high-dosage category" and "severe benzodiazepine-withdrawal syndrome". From everything I have read, I would say that it is highly likely that the chance of me suffering seizures at my usage levels is less than 1%. If you have personal evidence to the contrary, please tell me about it!

2. "valium is one that is was easy for me to quit. alot easier than than caffeine or cigarettes."

What is your problem with this? Are you accusing him of lying? Why would he lie about this?

3. If ya using more than 400mg of diaz a day for a few months than ya in trouble. but at least it valium.

Again I don't see the problem...this may be irrelevant to my personal case, but I believe he was giving an example of a situation in which you might expect to suffer severe withdrawals.

4. valium, temazepam, & valium.

Surely a simple typo? Does this really deserve to be highlighted?

5. its VERY ADDICTED but it's also VERY HARD TO GET ADDICTED TOO.

Ignoring the poor English, this is indisputably true. Unlike, say, opiates, it takes a while to get addicted to benzos. But as with, say, alcohol or GHB, the withdrawals can be much more severe.

Now, to the person who said "let's just say you get lucky and don't get a seizure, which is definitely a possibility. You will still go through mental hell"...here is some maths:

Let us suppose, for the sake of argument, that I have a very high "personal diazepam half-life". of, say, 84 hours, or 3.5 days (if we assume a lower half-life, which is likely, then everything I am about to say is more true). Then I can expect my blood levels of diazepam to halve twice per week. If I was taking 40mg a week, then I would stabilise on, roughly, a blood-level of 15mg diazepam. Now suppose I stop. Then within 4 days my blood levels of the drug will be less than 7mg. As I have done this many times and not felt any withdrawals whatsoever, we can safely assume that I am physiologically addicted to no more than a constant blood-level of 5mg. This is equivalent to taking less than 1.5mg diazepam per day (which itself is equivalent to less than 0.075mg xanax). Is it really a FACT that I will go through mental hell from quitting these levels?

I am honestly not trying to be a "tough guy". I simply want to know if I'm physically addicted or not. I don't plan to stop using valium completely, merely cut it down to levels at which I am not at risk of addiction.

Please...as much as I appreciate the concern, don't give scare stories just because you have had a severe benzo habit in the past and suffered for it. I'm looking for answers from people who have had small habits and quit.

Bro, you are physically addicted. Anon 54 has no clue what he is talking about.
 
One person even accused him of having a clouded mind from taking too many drugs, which I think is particularly low on these boards.

I "accused" him of having a clouded mind. His post was full of contradictions and nonsensical statements.

Why is it low to say that? And why particularly low on these boards?

It sounds like you have made up your own mind about how to go on with your use. You don't need to justify it to us.
 
This isn't really going anywhere! If you read my original post I simply asked for people who have been in a similar situation to me to share their experiences.

I'm still interested in this, so please let me know if you have any stories to tell of addiction to low dosages of benzos. Otherwise I'm not going to argue any more!

Day 6 now, and no withdrawal symptoms. Assuming I'm not dead in the next few days, I will update in a week or so for those interested.
 
Anon54 makes the same type of bullshit threads as you, OP. We spend time out of our days to give you guys well-thought out, articulated responses drawing from personal anectodes, when you guys choose to just ignore all the information opposing your viewpoints and absorb only the information that supports them.

Why did you even make this thread? Did you really think a bunch of people with personal experiences with benzo dependence, including some who have seized while discontinuing abruptly, were going to hold you hand and say, "hey, you're totally right, dude! Cold turkeying benzos? Why didn't we think of that?!"
 
^Basically.

Anon54 could have had a special experience. OP, that doesn't mean you will. You asked for people's personal experiences and got more than one, but only chose to listen to the one you wanted to listen to. I would listen to Guido, tricomb, Ergic and the others that have posted more sense on here. In the end, its up to you. I've only been on benzos for a few years (prescribed and otherwise) and yes, they are addictive. Yes, caffeine, nicotine and opiates are also addictive. But they're not benzos. With the long-acting ones you certainly can skip a few days and feel fine. But that doesn't mean you're not addicted....

My advice is echoing what the other posters have said here. Read up on taper plans or better yet, talk to a doctor who knows about benzos about one. Do not stop cold turkey.
 
Okay I'll keep talking! ;) Let's keep it civil shall we though guys?

Why did you even make this thread? Did you really think a bunch of people with personal experiences with benzo dependence, including some who have seized while discontinuing abruptly, were going to hold you hand and say, "hey, you're totally right, dude! Cold turkeying benzos? Why didn't we think of that?!"

Yes, with hindsight I admit it was perhaps a bit naive to expect to receive anything but worst-case scenarios on a forum dedicated to harm-reduction. However, here' s a question: at what point does harm-reduction become rumours and misinformation? Many governments have attempted the former by means of the latter, with disastrous results.

Now, consider the following bluelight threads:

http://www.bluelight.ru/vb/archive/index.php/t-545467.html?

http://www.bluelight.ru/vb/archive/index.php/t-221341.html

These posters were asking similar questions to me (I should have searched first I know!), and seemed to get much more reasonable advice. Also, I have now received 2 PM's from people who were basically answering my question (small habits of benzos in both cases, with few problems quitting in one case, and none in the other). These people obviously didn't want to actually post their answers, for fear of appearing irresponsible. All of this makes me think that perhaps these boards have become much more geared towards harm reduction, and less towards facts.

Of course the motivation is laudable. But I don't think it is healthy to have a situation where people are worried about posting anything other than worst-case-scenarios and horror stories...down that road lies ignorance. Surely far better to combine harm-reduction with reasonable advice (eg. "you should taper, but it is very unlikely you will have seizures or other serious symptoms"...rather than "DON'T COLD TURKEY! SEIZURES AND DEATH!").

Finally, everyone who has responded in this post seems to have had very large benzo habits. I didn't expect this, but I do understand it can probably be irritating for people to see someone apparently being nonchalant about something that has been a serious problem for them in the past. I apologise for any offence caused.
 
Even with low doses there is still risk of seizures. My main concern is how long you have been using it not the dose. Seeing as you are trying to take the cold turkey path I would like to offer you the advice of if you start to feel withdrawals and I hope you would know the difference between flu like symptom withdrawals vs anything worse. If you start to feel worse than simple flu like symptoms please take a low dose of benzo to prevent anything bad occuring. A mere couple of mg will be enough to keep you safe.

Take care.
 
a final update as promised...for the benefit of future readers who might be in a similar situation to me (and also to reassure everyone I'm still alive!). I went 9 days and no withdrawal symptoms. At that point I assumed, with great relief, that there was no way I could be physiologically addicted, and took some more diazepam (not in celebration! It was fairly necessary as I was taking a break from kratom, to which I most assuredly am physiologically addicted).

However, this is just me, and everyone's different. Probably if you are in a similar situation to me then you should follow the advice which was very vehemently given in this thread, and taper your use to as little as possible, as you are clearly playing with fire taking benzos regularly for a prolonged period.

Finally, I found an interesting fact about the half-life of diazepam: in Clinical Anesthesia (Barash, Cullen, et al) it is stated that "the half-life of diazepam in hours is approximately equivalent to the patient's age in years". (The link should take you to the chart via google books).

Very interesting, and useful to know. This means that, for example, if you are 24 years old you can expect the amount of diazepam in your system to decrease by half each day. Liver function also seems to affect it (poorly-functioning liver = increased half-life), while gender doesn't. So if you drink a lot, or are older, you are more at risk of addiction.

Regardless, I intend to use it as rarely as possible from now on, as I don't want to lose such a wonderfully useful tool.
 
I've been taking benzos off and on now for a few years (...) For the last couple of years I've stuck to valium (well, generic diazepam), and I'd say I have probably averaged 30mg-40mg/week, usually taken in doses of either 5mg or 10mg at a time, 20mg maximum. Typically 2 days using 10mg, and 2 using 5mg each week.

Using diazepam 4 times a week for say 3 months, with prior benzo use to that, i doubt you will not get any withdrawls at all... as you quit rightly stated diazepam has an extremely long half-life, meaning you're also right in stating that the w/d won't come straight away, it will probably take at least a sew days

BUT, remember cold turkeying off benzos is a recipe for relapse, largely due to the rebound anxiety from stoping the benzo abruptly... not to mention the seizure risk

I sggest you o see your dotor and elaborate a suitanle taper plan, the taper will be short since you havve not been using long... but it will make it a painless process, with a far lower chance of relapse..

Feel free to PM me if you want some suport, ideas/suggestions, i dunnno, whatever I can offer, i'll do my best
 
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OK...I have heard it is dangerous. However, as far as I have read there is no incidence of serious physical symptoms such as seizures unless the habit is very large and long-term (I fully accept that I may well be dependent, but this is certainly a relatively small habit). Plus the long half-life of diazepam means that withdrawals (if there are any) will come on gradually. Meaning that, surely, if I have some to hand, the worst I can expect is to start feeling pretty shitty, at which point I would take a small dose, and repeat?

Or are you suggesting I could actually just suddenly break down/have a seizure? I respect your concern and desire for damage limitation, but this seems a bit drastic!
Just wanted to add my bit here. I took benzos for three-four months, the doses were much higher than what you take and also it wasn't diazepam (it was tetrazepam but no one knows that one so whatever, but anyway it has a much shorter half-life) but the fact of the matter is I wasn't addicted for thaaaaaaaat long...just a few months (well I'd been taking them for about six months prior to that but for an actual physical problem and in very small doses). So I thought I'd be okay quitting cold turkey, but well I wasn't, had a seizure and ended up in the hospital. Unfortunately I can't help you with your particular issue because I don't know enough about diazepam but all I can say is, don't underestimate the danger of quitting benzos cold turkey. From what you've said there's a huge chance that you're now physically dependant on them, don't risk your life (this sounds dramatic but it's sort of true) because it's *unlikely* you'll get a seizure. It can happen.
 
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