I assume we're talking psilocybe mushrooms here? Did psilocybe semilanceata for a short while about 26 years ago. Really enjoyed the first time, was a pretty magical experience but was doing them too often and on my own and they soon lost their magic. The last time I did them around that time, I was sat on a hill on a beautiful sunny day, overlooking the town and the shimmering sea and should have felt on top of the world but instead, felt like there was no point to life or anything and felt that everything that was wrong in the world was my fault. I've never felt suicidally depressed like I did that day.
I tried them about 5 years later and had a large hit of hash which made me feel really sick and I just curled up with my eyes shut until I felt normal again. Took a few along with plenty of MDMA and amphetamines and a bit of coke at a rave 12 years after that and had a fantastic time. They really enhanced the colours of the strobe lighting. Took a few with MDMA at a beach party a year later and had a good time. That was 8 years ago. I expect I'll do them again one day but I'm in no hurry.
Advise treating them with respect.