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  • BDD Moderators: Keif’ Richards

Bupe Combining buprenorphine with tramadol?

Rattlesnake-Retold

Greenlighter
Joined
Aug 19, 2025
Messages
2
I've been on doctor prescribed buprenorphine (no naloxone) for... a while now. Started at 32mg/day and have tapered to 8mg/day. Recently, I broke my leg and for obvious reasons I didnt want to be put on full agonist opioids. Over the last few weeks I've burned through my entire "backup" supply I had accumulated through the tapering process. Now I've completely run out a couple days shy of my refill date. I know I have a few tramadol and a couple MScontins stashed away so my question is this: Can you take tramadol before OR after a dose of bupe without causing precipitated withdrawals? I know it's not going to be as effective but I'm not looking to get high just stave off withdrawals for a couple of days until I get my script
 
Tramadol is a bit complicated but I guess thinking of it as being similar to codeine is as simple as I can go without lying. But it does reduce pain in ways other than classic opioids such as morphine. So it MAY help some. Obviously morphine is the 'gold standard' opiate.

In both cases, any buprenorphine in your body simply competes for receptor occupation. Even a high dose of codeine will break through a low dose of buprenorphine, I've consumed 4mg of buprenorphine in the morning and when I took codeine in the evening, it worked with no subjective differences at all.

As with all things, YMMV and if I'm honest, it's always better to at least be honest with your clinician. I know in some nations that's a risky stratergy but I would argue that a broken limb means pain control is not an unreasonable expectation. I don't say pain relief or analgesia. Expectation should be that if pain is preventing you from functioning, sufficient analgesia to control that pain to a level where you can function is the goal. Totally blocking all pain is a bad idea as pain is a vital warning message.

I don't know where you are but for pain, 200-400ug TID is normal in the UK. More than that likely doesn't increase it's analgesic action and is certainly where nasty side-effects can creep in.
 
When I had a constant tramadol script'
I had a couple friends that were on daily 2 to 4 mg bupre' they claimed it a great compliment alongside the bupre'

I tried it a few times with only positive side effects... and they said the pw's were non existant
 
And what about morphine? Say I took 60mg around midnight. How long would i have to wait to take the bupe again?
 
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