Mental Health combating ADHD stimulant tolerance

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Bluelighter
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Apr 24, 2019
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Chicago, IL, US
I have been diagnosed with so many things at this point and I take 5 psychiatric medications, 6 if I include my occasinal sleeping pill.

I think that ADHD and anxiety are the two main issues, and my depression and mood issues would resolve themselves with these two under control and I could reduce how many medications I take.

I've been on Ritalin (IR, SR, and LA) Focalin XR, Adderall IR, Vyvanse (initial treatment and current medication), and Strattera.

I build up tolerance to the stimulants so fast, with true help capping out at 2 weeks to a month. But when I go off, I'm a wreck for about two months and then slip into a depressed, dissacocisted, non functional wreck.

For Vyvanse and Adderall, they work decently and then the effectiveness wears off to almost nothing within a month or two, organization of thinking and ability to process information wise. After that they still keep me out of living in a haze and missing work, school, forgetting what day/month/year it is, and (somewhat) from randomly sleeping.

Ritalin and Focalin go from doing everything I need and bringing me to my full potential, as people say. Everyone tells me that I'm super intelligent but my mind is such a wreck that I can't show it on paper. My therapist wanted me to take an IQ test because she said my information processing and speed of thought were unlike anything she'd ever seen and she didn't understand how it was possible and my speaking and behavioral patterns etc. After the methylphenidates are really effective, they throw me into a jittery hyped up mess where I have an underlying sense of fear and can't process information because I'm so overstimulated.

Straterra did nothing. Absolutely nothing. No side effects even. Might as well have been a sugar pill.

Wellbutrin is prescribed to me for depression and it's helped more than any ssri alone or with an antipsychotic that I've ever taken, although I take Lexapro with it.

I'm wondering if anyone has had success with Kapvay or guanfacine, with a stimulant or alone. When I took straterra I was on zoloft and abilify as well so I'm wondering if it might help the second time around because I'm on Wellbutrin, Lamictal, Vyvanse, Xanax, and Lexapro now. My pdoc is considering taking off the lexapro and I want to try it. The only other one I could maybe stop is Lamictal but Lamictal and Wellbutrin have helped my depression more than any Serotinin affecting drug I've ever been prescribed. Xanax is the only thing that helps me enough to get through the day, I've been through Vistaril, Buspar, Ativan, Klonopin, and Gabapentin. Out of those, Vistaril and Gabapentin were the most effective by fat and Klonopin made no impact which I still don't understand as it is a benzo.

Almost all of the things that I'm stressed and depressed about are directly related to my ADHD so I'm wondering if anyone has a way around stimulant tolerance, and if maybe a stimulant + xanax + wellbutrin combo might be good.
 
If you do have a mood disorder, the lamictal is pretty critical. And like you said, it can help with depression.

If lexapro was dropped, that itself might boost the overall effectiveness of the other stimulants.

Do you take wellbutrin IR or XR?
 
Well the effects on focus if you want to focus are consistent. Stimulants are really not mood agents, unless they secondarily improve mood through improving ADHD/energy. Like most psych meds, their effects drop into the background with chronic use. In fact you're really not supposed to get a mood lift at all from them. That would be going down the wrong road.

Adderall helped me. But from stories of others if you decide to tweak and take more than you're given even a few times, then you'll be going down into that dark chasm of addiction and pretty taxing effects on the brain.

With respect, but in honesty, I really think you'll either have to not use stimulants often, or get used to the fact that stimulants really aren't antidepressants/anxiolytics.
 
I know they're not there to help with anxiety and depression - my issue is that the effects on focus are not consistent for me at all, that's the part that drops off quickly and then they start to alter my mood which is awful. I only take prescribed doses and don't play with them.
 
If I had to speculate I would guess your confusing the high stopping with the drug losing effectiveness. You'll never be able to keep that stimulated buzz going for long no matter the dose. And like AMP said ideally you wouldn't notice the drug working at all. You probably need to adjust your expectations
 
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