• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

Closest mephedrone analogues. possibly legal?

R

rzrzrz

Greenlighter
Joined
Sep 28, 2010
Messages
7
Heya all.
Our theoretical replacement for mephedrone.
To be trendy I call it RZ-1, RZ-2, RZ-3 etc. :)

RZ1 - RZ4 should be illegal in UK but legal in other world.
RZ6 - RZ11 should be legal everywhere in the world.

93667538.png


In my opinion this betaketones should be the closest to meph in effects.
1) RZ-1 (4methylbuphedrone) may be less euphoric and be more stimulant like drug.
2) RZ-2x should be perfect alternative to meph. but i have some doubts about it's toxicity.
variants:
2.a) fluoromethyl - Main variant.
2.b) difluoromethyl - optional.
2.c) trifluoromethyl - optional.
3) RZ-3 and RZ-4 may be weak but longer acting euphoretics with stimulant effects.

Aaaaaaand my super, SUPER fresh, novel and probably psychoactive analogues of mephedrone. (and also probably toxic/neurotoxic/deadly )
Legal for all, even for guys from UK. (stop eating caffeine)

86129370.png


1) RZ-6 (Methiodrone). Just beta ketone version of old and known 4-MTMA. Verified variant.
2) RZ-7, RZ-8 +100000 variations. Silicium modifications.
RZ-7 i called Silephedrone This should be very close to original substances.

Selenium line chems look like this:

87720532.png


Any comments? :)
I think the most interesting are
RZ1, RZ2, RZ7, RZ10 and RZ12 (no image, formula - 4-ethylmethcathinone, 4-EMC).
What do you think ? Your opinion ?
Lets discuss :)
 
Selephedrone looks real and possible to make. Analogy with Shulgin's 2c-se.
 
Oh man, where to start...

You can personally make the para-selenohydryl compound and test it on yourself. Might wanna take a look at the toxicology regarding para-methylthioamphetamine, too. Nevermind neuronal cells or rats or papers published about NDRIs/amphetamine-type releasers, this stuff should go straight into your stomach.
 
I have some doubts about bk version of 4-MTA. but as i remember deketo version of Methedrone has bad reputation. and the methedrone itself not as bad. so may be things change when we add = O at beta position.
And, btw, deketo version of mephedrone wasnt very interesting too.
 
Again! Super new and super fresh novel possibly active euphoretic!
RZ-13 !
43900715.png


Analogy with dimethocaine NH2 substitution on phenyl ring :)
any comments? :)
 
anything after rz-4 and you're playing with fire.

probably best to abandon the methcathinone skeleton at this point. i'd like to see more work done with non-nitrogen containing stimulants, as these would clearly fall outside any analogue law

220px-O-2172_structure.png
 
Anyone can draw compounds. It takes a bit more than that to earn the right to name it!

If you're interested in structure-activity relationships, I recommend you look at some of the relevant scholarly material, you might find it interesting. You'll also find that there are many older stimulant/entactogens which were far superior to mephedrone (phenmetrazine, 4-methylaminorex, AET).
 
Some 4-methaminorex analogs sound alot more interesting to me. The first four will probably be available soon if not already. The only reason to make them would seem to b to get around the meph ban in the Uk, but I'm pretty sure they are already as illegal as meph so what would that acheive? The rest I have no idea as to affects or safety, might prove interesting, but I'll let a few thousand lab rats (probably of the two legged variety) try them before I would consider it. And why the obsession with cathinones? Why not the amphetamine versions?

BTW this is FS, my girl was logged in and I forgot to switch accounts
 
RZ1-4 look viable as cheap meph analogues, assuming you can find the starting ketone.
RZ6 as stated above is probably going to go Rambo on your neurons and/or be an MAOI.
RZ7 and 8 would decompose on contact with heating or not even form. Silanes like to react with water to form silicon dioxide (sand).
RZ9 is likely a MAOI that will grill your brain.
RZ10 is likely too polar to be effective and maybe toxic. (Humans aren't supposed to intake a lot of selenium)
RZ11 will probably decompose.



Maybe these? #1 would have markedly increased duration because it could not be oxidised to a ketone. No possible tox problems with that, no sir.
 
well, old stimulants i know too. When i was younger i tryed a lot of them. even not really popular.
The idea was to get some really active cathinone but avoid UK cathinone ban.

If change basis and do not try to modify MCAT structure here may be ideas like use instead of phenyl another aromatic ring:

42204247.png


I always leave = O group on beta caz of idea short acting drug.

2)or use instead of A-methyl-PEA B-methyl-PEA

77579421.png
 
I suggest you read and UNDERSTAND the law before trying to circumvent it. Not all of the compounds you have said are legal are.
 
You must log in or register to reply here.
Top