chemistry Q re levo-amp dex-amp

[movbikwaet]

I dont know anything about chemistry but I am asking this out of curiosity.

I was messing around with google looking up phenylalanine and I came across an article wich said if you use d-phenylalanine you get dextroamphetamine. I was under the impression it is psuedoephedrine, d-ephedrine or l-ephedrine use wich is the determining factor on wether dexamphetamine or levoamphetamine would be synthesised.

 

[hussness]

No discussion of synthesis is allowed on this board. If you could successfully perform those reactions you probably would know something about stereochemistry, so it's a mute point anyway.

 

[movbikwaet]

Ok sorry, I was just curious anyway, cause I read conflicting articles, and I like to educate myself.

 

[hussness]

That reaction series should result in retention of configuration since there is no chance for the alpha-methyl to get replaced.

 

[DadeMurphy]

With phenylalanine you don't go through pseudoephedrine or ephedrine, it is the stereochemistry of the precursor you are using that influences the stereochemistry of the product. And the reaction in question proceeds with a retention of stereochemistry as hussness said.

 

[johanneschimpo]

No discussion of synthesis is allowed on this board. If you could successfully perform those reactions you probably would know something about stereochemistry, so it's a mute point anyway.

no, its a moot point