Chapter II: The Abyss is Eternal !

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mal3volent said:
do you know the cdc recommends wearing a mask while fucking?
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Yeah dude, following CDC guidelines has never been more fun!

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Did you know It's actually impossible for Meth to actually cause brain damage unless you had a traumatic event happen like a car crash or some shit, but the Brain is the 2nd Strongest Muscle in your body. Your heart is 1st because it's constantly active, but the brain controls everything in your body including releasing dopamine thru the Pineal gland. You took too much and your brain got used to having high Dopamine levels, it's all a huge part of your imagination in my theory. I was diagnosed with Schizophrenia for untreated ADHD growing up. I didn't have the luxury of stimulants growing up. But imbalance dopamine can cause hallucinations, having a hard time focusing, Hyper activity, all kinds of symptoms. In conclusion no it's not technically "Brain Damage"
 
Coxenormous said:
Did you know It's actually impossible for Meth to actually cause brain damage unless you had a traumatic event happen like a car crash or some shit, but the Brain is the 2nd Strongest Muscle in your body. Your heart is 1st because it's constantly active, but the brain controls everything in your body including releasing dopamine thru the Pineal gland. You took too much and your brain got used to having high Dopamine levels, it's all a huge part of your imagination in my theory. I was diagnosed with Schizophrenia for untreated ADHD growing up. I didn't have the luxury of stimulants growing up. But imbalance dopamine can cause hallucinations, having a hard time focusing, Hyper activity, all kinds of symptoms. In conclusion no it's not technically "Brain Damage"
Click to expand...

I don't care if you want to spread stupid memes or whatever and I know this is the Abyss, but you are straight up and unequivocally wrong. Methamphetamine has major damaging effects on the brain and you are spreading misinformation:

What Are the Effects of Meth Use and Abuse?
  • Increased neuronal death: The use of methamphetamine is associated with decreases in the number of neurons in the CNS. The ability of the CNS to regenerate these neurons is limited, and in many cases, the loss of neurons cannot be recovered. The body of evidence indicates that chronic use of methamphetamine can result in diffuse brain damage that occurs via neuronal death. Neuronal death occurs in a number of areas of the brain as a result of meth abuse that include but are not limited to:
    • The hippocampus: a crucial structure for the ability to remember and learn new information
    • The striatum: a structure in the subcortical areas of the brain that is crucial in movement and certain aspects of directed attention
    • The parietal cortex: a structure that is involved in being able to visualize objects in space and in the memory of nonverbal material
    • The frontal and prefrontal cortex: areas of the brain that are crucial in human cognition, particularly in reasoning, complex attention, problem-solving, and the inhibition of behaviors that might be damaging
    • A number of subcortical structures: including the basal ganglia, the reward center, the limbic system, and others
    • The cerebellum: controls various aspects of movement and is involved in a number of cognitive functions
Decreased gliogenesis
Neurons are not the only cells in the CNS. A number of other cells generally referred to as glial cells also comprise the central nervous system. These cells have a number of responsibilities, including signaling capacities, fighting infection, developing myelin (the fatty sheath or white matter that neurons used to effectively communicate), etc. The use of methamphetamine has also been associated with increased damage and death to these cells in a number of brain areas, particularly in the prefrontal cortex where a number of important functions, such as attention, planning, abstract thinking, judgment, etc., occur. In addition, methamphetamine use is associated with a decrease in the production of glial progenitor cells, which are immature glial cells that differentiate into different types of glial cells.

Decreased white matter
As certain glial cells (oligodendrocytes and Schwann cells) become damaged and the ability to produce myelin is affected in both the brain and spinal cord, the amount of white matter in the CNS is decreased. White matter (myelin) aids in efficient singling between neurons in the CNS. White matter is located on the axons (signaling portions) of the neurons, and as this matter is decreased, neurons become less efficient in transmitting their signals. This results in a number of functional deficits.

Decreases in the levels of dopamine and serotonin transporters
Dopamine and serotonin transporters are specialized cells in the CNS that function to remove the dopamine and serotonin that have been released from the neurons into the synaptic cleft (the space between neurons) and bring them back into the cell where they can be repackaged for reuse. This partially results in the psychoactive effects of meth, but also leads to later dopamine and serotonin depletion because the neurons have less dopamine to use later. This can result in a number of extreme mood effects, such as initial extreme euphoria followed by extreme periods of depression, apathy, and hopelessness.

Increased glutamate calcium in the brain
Increases in the neurotransmitter glutamate (the major excitatory neurotransmitter in the brain) and calcium are often associated with neurotoxic effects in the brain as a result of the neurons being overly excited and continuing to fire to the point of actually damaging the system. If not modulated, this can result in significant damage throughout the central nervous system.

Neurotoxic effects that damage the dendrites of the neurons
A number of these neurotoxic effects lead to significant damage in the dendrites of neurons. The dendrites of neurons are the receiving portions of the neurons that receive the chemical singles from other neurons. This damage prevents the neurons from communicating effectively and can affect a number of cognitive and motor functions.


Live your life how you want, I don't judge, but when you spread dangerous falsehoods on a harm reduction site, you are doing a disservice to the community. There's jest, which is fine, it's the Abyss, but if you're joking, it's really not clear and not very funny frankly.
 
BK38 said:
I don't care if you want to spread stupid memes or whatever and I know this is the Abyss, but you are straight up and unequivocally wrong. Methamphetamine has major damaging effects on the brain and you are spreading misinformation:

What Are the Effects of Meth Use and Abuse?
  • Increased neuronal death: The use of methamphetamine is associated with decreases in the number of neurons in the CNS. The ability of the CNS to regenerate these neurons is limited, and in many cases, the loss of neurons cannot be recovered. The body of evidence indicates that chronic use of methamphetamine can result in diffuse brain damage that occurs via neuronal death. Neuronal death occurs in a number of areas of the brain as a result of meth abuse that include but are not limited to:
    • The hippocampus: a crucial structure for the ability to remember and learn new information
    • The striatum: a structure in the subcortical areas of the brain that is crucial in movement and certain aspects of directed attention
    • The parietal cortex: a structure that is involved in being able to visualize objects in space and in the memory of nonverbal material
    • The frontal and prefrontal cortex: areas of the brain that are crucial in human cognition, particularly in reasoning, complex attention, problem-solving, and the inhibition of behaviors that might be damaging
    • A number of subcortical structures: including the basal ganglia, the reward center, the limbic system, and others
    • The cerebellum: controls various aspects of movement and is involved in a number of cognitive functions
Decreased gliogenesis
Neurons are not the only cells in the CNS. A number of other cells generally referred to as glial cells also comprise the central nervous system. These cells have a number of responsibilities, including signaling capacities, fighting infection, developing myelin (the fatty sheath or white matter that neurons used to effectively communicate), etc. The use of methamphetamine has also been associated with increased damage and death to these cells in a number of brain areas, particularly in the prefrontal cortex where a number of important functions, such as attention, planning, abstract thinking, judgment, etc., occur. In addition, methamphetamine use is associated with a decrease in the production of glial progenitor cells, which are immature glial cells that differentiate into different types of glial cells.

Decreased white matter
As certain glial cells (oligodendrocytes and Schwann cells) become damaged and the ability to produce myelin is affected in both the brain and spinal cord, the amount of white matter in the CNS is decreased. White matter (myelin) aids in efficient singling between neurons in the CNS. White matter is located on the axons (signaling portions) of the neurons, and as this matter is decreased, neurons become less efficient in transmitting their signals. This results in a number of functional deficits.

Decreases in the levels of dopamine and serotonin transporters
Dopamine and serotonin transporters are specialized cells in the CNS that function to remove the dopamine and serotonin that have been released from the neurons into the synaptic cleft (the space between neurons) and bring them back into the cell where they can be repackaged for reuse. This partially results in the psychoactive effects of meth, but also leads to later dopamine and serotonin depletion because the neurons have less dopamine to use later. This can result in a number of extreme mood effects, such as initial extreme euphoria followed by extreme periods of depression, apathy, and hopelessness.

Increased glutamate calcium in the brain
Increases in the neurotransmitter glutamate (the major excitatory neurotransmitter in the brain) and calcium are often associated with neurotoxic effects in the brain as a result of the neurons being overly excited and continuing to fire to the point of actually damaging the system. If not modulated, this can result in significant damage throughout the central nervous system.

Neurotoxic effects that damage the dendrites of the neurons
A number of these neurotoxic effects lead to significant damage in the dendrites of neurons. The dendrites of neurons are the receiving portions of the neurons that receive the chemical singles from other neurons. This damage prevents the neurons from communicating effectively and can affect a number of cognitive and motor functions.


Live your life how you want, I don't judge, but when you spread dangerous falsehoods on a harm reduction site, you are doing a disservice to the community. There's jest, which is fine, it's the Abyss, but if you're joking, it's really not clear and not very funny frankly.
Click to expand...
Oh yes! You finally learned how to Google!
 
BK38 said:
I don't care if you want to spread stupid memes or whatever and I know this is the Abyss, but you are straight up and unequivocally wrong. Methamphetamine has major damaging effects on the brain and you are spreading misinformation:

What Are the Effects of Meth Use and Abuse?
  • Increased neuronal death: The use of methamphetamine is associated with decreases in the number of neurons in the CNS. The ability of the CNS to regenerate these neurons is limited, and in many cases, the loss of neurons cannot be recovered. The body of evidence indicates that chronic use of methamphetamine can result in diffuse brain damage that occurs via neuronal death. Neuronal death occurs in a number of areas of the brain as a result of meth abuse that include but are not limited to:
    • The hippocampus: a crucial structure for the ability to remember and learn new information
    • The striatum: a structure in the subcortical areas of the brain that is crucial in movement and certain aspects of directed attention
    • The parietal cortex: a structure that is involved in being able to visualize objects in space and in the memory of nonverbal material
    • The frontal and prefrontal cortex: areas of the brain that are crucial in human cognition, particularly in reasoning, complex attention, problem-solving, and the inhibition of behaviors that might be damaging
    • A number of subcortical structures: including the basal ganglia, the reward center, the limbic system, and others
    • The cerebellum: controls various aspects of movement and is involved in a number of cognitive functions
Decreased gliogenesis
Neurons are not the only cells in the CNS. A number of other cells generally referred to as glial cells also comprise the central nervous system. These cells have a number of responsibilities, including signaling capacities, fighting infection, developing myelin (the fatty sheath or white matter that neurons used to effectively communicate), etc. The use of methamphetamine has also been associated with increased damage and death to these cells in a number of brain areas, particularly in the prefrontal cortex where a number of important functions, such as attention, planning, abstract thinking, judgment, etc., occur. In addition, methamphetamine use is associated with a decrease in the production of glial progenitor cells, which are immature glial cells that differentiate into different types of glial cells.

Decreased white matter
As certain glial cells (oligodendrocytes and Schwann cells) become damaged and the ability to produce myelin is affected in both the brain and spinal cord, the amount of white matter in the CNS is decreased. White matter (myelin) aids in efficient singling between neurons in the CNS. White matter is located on the axons (signaling portions) of the neurons, and as this matter is decreased, neurons become less efficient in transmitting their signals. This results in a number of functional deficits.

Decreases in the levels of dopamine and serotonin transporters
Dopamine and serotonin transporters are specialized cells in the CNS that function to remove the dopamine and serotonin that have been released from the neurons into the synaptic cleft (the space between neurons) and bring them back into the cell where they can be repackaged for reuse. This partially results in the psychoactive effects of meth, but also leads to later dopamine and serotonin depletion because the neurons have less dopamine to use later. This can result in a number of extreme mood effects, such as initial extreme euphoria followed by extreme periods of depression, apathy, and hopelessness.

Increased glutamate calcium in the brain
Increases in the neurotransmitter glutamate (the major excitatory neurotransmitter in the brain) and calcium are often associated with neurotoxic effects in the brain as a result of the neurons being overly excited and continuing to fire to the point of actually damaging the system. If not modulated, this can result in significant damage throughout the central nervous system.

Neurotoxic effects that damage the dendrites of the neurons
A number of these neurotoxic effects lead to significant damage in the dendrites of neurons. The dendrites of neurons are the receiving portions of the neurons that receive the chemical singles from other neurons. This damage prevents the neurons from communicating effectively and can affect a number of cognitive and motor functions.


Live your life how you want, I don't judge, but when you spread dangerous falsehoods on a harm reduction site, you are doing a disservice to the community. There's jest, which is fine, it's the Abyss, but if you're joking, it's really not clear and not very funny frankly.
Click to expand...
 
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