Blowmonkey
Bluelight Crew
Flavonoids, terpenoids - what do you know?
Can anybody get their hands on these two articles?
(1) McPartland, J.M., Russo, E.B. (2001) Cannabis and cannabis extracts: greater than the sum of their parts? Journal of Cannabis Therapeutics 1 (3/4) 103–132.
(2) Gierienger D. Medical Cannabis potency testing. Bulletin of the Multidis-ciplinary Association for Psychedelic Studies 1999;9(3):20-22.
Because I've been told by someone on Overgrow that the variance in effects from different cannabis strains is not due to different percentages of cannabinoids, but flavonoids and terpenoids!
I mean, this is pretty confusing to me..
Can anybody get their hands on these two articles?
(1) McPartland, J.M., Russo, E.B. (2001) Cannabis and cannabis extracts: greater than the sum of their parts? Journal of Cannabis Therapeutics 1 (3/4) 103–132.
(2) Gierienger D. Medical Cannabis potency testing. Bulletin of the Multidis-ciplinary Association for Psychedelic Studies 1999;9(3):20-22.
Because I've been told by someone on Overgrow that the variance in effects from different cannabis strains is not due to different percentages of cannabinoids, but flavonoids and terpenoids!
http://haworthpressinc.com/store/SampleText/4513.pdfMEDICAL CANNABIS TODAY
Drug Cannabis available to the medical user can be assigned to one of two categories. Marijuana (domestically produced and imported cannabis flowers) is nearly always grown from high-THC varieties (up to 20 to 25 percent dry weight in trimmed female flowers) containing very little CBD. Hashish or charas (compressed cannabis resin) is made from varieties that are predominantly THC (up to 10 percent), but they often contain up to 5 percent CBD. Clean high-THC profiles result from marijuana growers mak-ing seed selections from individual favorable plants with high THC levels. Hashish is produced by bulk processing large numbers of plants, and, there-fore, growers are unable to make seed selections from individual particu-larly potent plants so the CBD level tends to remain at more natural limits. Hashish cultivars are bred for resin quantity rather than potency, so the farmer selects plants and saves seeds by observing which ones produce the most resin, rather than if it contains THC or CBD. Afghan populations con-tain approximately 25 percent plants that are rich in CBD with little THC, 50 percent that contain both CBD and THC, and 25 percent that contain lit-tle CBD and are rich in THC. CBD is suspected of having effects on the pri-mary psychoactive compound THC and in a medical setting it may also have useful modulating effects on THC or valuable effects of its own.
How-ever, analytical surveys of 80 Cannabis varieties in the Netherlands D.W. Pate, personal communication, 1999) and 47 samples in California 4 show that nearly every sample contained predominantly THC usually with less than 5 percent of the other combined cannabinoids. Higher levels of THC and other medically effective cannabinoids and terpenoids are healthier for patients using smoked cannabis as they can smoke less to achieve the same dosage and effect.
http://www.pavpub.com/pavpub/useredit/journals/K511202c.pdfWhile much of the product development is focusing on specific cannabinoids, many herbalists support anecdotal reports from patients, which contend that the natural whole plant works better than a single agent. Although plants may contain hundreds of compounds, herbalists believe that the ‘…polypharmaceutical herbs provide two advantages over single-ingredient synthetic drugs: (1) therapeutic effects of the primary active ingredients in herbs may be synergised by other compounds, and (2) side effects of the primary active ingredients may be mitigated by other compounds’ (McPartland and Russo, 2001, p.104). Cannabis contains more than 400 compounds. There is good evidence to show that secondary compounds in Cannabis may enhance the beneficial effects of THC, while other cannabinoids and non-cannabinoid compounds may reduce the side effects of THC. Terpenoids and flavonoids found in Cannabis have been shown to exert beneficial effects as well as THC (McPartland and Russo, 2001).
I mean, this is pretty confusing to me..