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Cannabis action on opioid receptors

^
Haha I can only imagine what 2c-i and MDMA were like together %)

But to your point, sure, not everything goes well with weed. But opiates sure do, that was my point about synergy in this particular case, it certainly doesn't work the same way with with any substance. Pot can make things alot worse or alot better, it all depends on what your combining it with.
 
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