Opioids Can caffeine counteract mild respiratory depression?

[blight12]

Rather to much HR then to little. The mods and contributing members have a tough job when its peoples lives at stake. We shouldn't get annoyed or take offense at the effort, strongly toned not, just saying...

 

[selfassuredfreq+]

I don't have to look up anything son, I'm the specialist and you're the dude not knowing what you're talking about so you have to provide the quotation, which you haven't, because there is no quotation. I'm probably wrong to waste my time with you but I'll do it for other people reading this:

Speedball is basically taking a deadly dose of Heroin and relying on the cocaine to dodge the respiratory depression. Since the cocaine wears off sooner, you might die from the opioid but if you keep re-dosing the cocaine, you will not. First of all, taking a deadly dose of Heroin is idiotic, regardless of the circumstance. All the cocaine does is it actually PREVENTS the overdose and respiratory depression, so the combination of both is much more beneficial than taking the deadly dose of Heroin alone, after which you certainly die!

I'm through with this. You know nothing man.

Ok we don't need immature suburban kids running around in here, speedballing has nothing to do with doing a deadly dose of heroin! That's idiotic!
It's a regular dose of heroin injected with cocaine, so you get the extra euphoria from the cocaine then feel the dope when you come down.



As for the reply to the thread: Caffiene doesn't act like common stimulants like cocaine and amphetamine. It blocks the adrino receptors(Sleep hormones) And allows dopamine and serotonin to flow more freely. I don''t think caffiene increases the CNS or RS enough to effect an opiates depression like cocaine and such.

Besides 10MG of oxycodone is a low dose and if you were still concious your not dieing of respritory depression probably

 

[Diacetylmorphan]

Um.. Cocaine potentates heroin and can make its effects stronger, so a regular dose of heroin combined with cocaine can lead to OD when the dope high takes over. Just saying,
Caffeine actually does open up your lungs and stimulate breathing to a small extent but in an overdose situation it will not be helpful besides hopefully keeping one from fading to black and breathing long enough to get some help.

 

[down508]

mild, maybe. but I doubt it would do much. if its so mild that caffeine would make a difference then I see no reason why you would bother trying to counteract it.

and to the guy above, cocaines does not potentiate the respiratory depressant effects of heroin, it actually does the opposite. where people run into problems, and what I suspect is throwing you off, is they do a certain amount of heroin and cocaine in a shot, the cocaine causes them to feel the depressant effects of the heroin less so they take more heroin. when the cocaine wears off the full effects of the heroin are realized and they overdose. if you do say 300mg of heroin one day and do 300mg plus 70mg cocaine another day after the cocaine wears off the heroin will not cause more resp. depression then it did with just heroin on its own. cocaine potentiates the euphoric effects of heroin due to the dopamine rush but aside from a slight crash (if you only do one shot of cocaine) it wont make much of a difference after the cocaine wears off.

 

[blight12]

Yeah coke might potentiate the good effects through synergy but the only real risk is being able to take more opiates and then the coke wearing off. Coke doesnt make that risk worse through other means then that.

 

[Swimmingdancer]

^It can. For example too much cocaine can actually cause respiratory deperession.

Anyway, on the topic of using stimulants to combat opioid overdoses, it's not a wise idea and there are already threads that go into detail as to why. But one of the main risks is that even if it helps, a person may temporarily improve from taking an amphetamine and then not seek proper medical attention. Then the amp wears off and they stop breathing. Another problem is if someone is in serious danger from an opioid overdose how are you going to give them the amp, inject it and guess at what an effective yet safe dose may be?

Ksa why are you a "specialist"? Just because you mix uppers and downers and are still alive? Doesn't mean it's free from risks, and it really depends on what they are, the doses, the ROA, etc.

 

[tricomb]

Yeah I once made a thread asking what people thought about methamphetamine helping during opioid overdose due to it being a ridiculously potent CNS stimulant, and since amphetamine's are proven to be respiratory stimulants, I was curious about what might happen hypothetically if someone were given a dose of amphetamine as a last resort option to save a persons life when naloxone wouldn't be delivered in time, but I'm pretty sure the consensus was that no, it would not help reverse the CNS depressant overdose.

It's hard to find good information / studies on this subject.

 

[Steven_Tyler77]

To the OP: your friend hasn't probably overdosed in any way. I guess she just got scared. It happened to me too, in my heyday (and with a weaker opioid too - codeine). Perhaps she wasn't accustomed to the sedated feeling and it frightened her. Caffeine might have helped, in counteracting the drowsiness... Now, if she wants to try codeine, let her start on a low dose. Perhaps 30 mg codeine is a good starting dose (recommended by Erowid and working really well for me, when my tolerance is low). She can build up from there, if she wants more, but, if she got scared the first time, she can panic again, even with codeine, so lower doses are safest...

As to the topic of whether uppers can counteract opiate OD, while not being an expert, I remember having read a while back on some harm reduction forum (perhaps even this one) that taking stimulants during an opiate overdose, by increasing heart rate, actually leads to getting more of the opioid drug faster into one's system, which leads to even more severe adverse health effects and ultimately increases the respiratory depression. What do you make of it?