Bup, Naltrexone and Psychotherapy for Prescription Opioid Abuse (Burlington, VT)

nuke

nuke

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Effective Treatment for Prescription Opioid Abuse

There has been an alarming increase in abuse of prescription opioids in recent years. This project aims to develop an effective outpatient treatment for prescription opioid (PO) abuse that combines an intensive behavioral therapy with a pharmacotherapy regimen of buprenorphine detoxification and naltrexone maintenance.

Estimated Enrollment: 210
Study Start Date: April 2006
Estimated Study Completion Date: March 2010
Estimated Primary Completion Date: March 2010 (Final data collection date for primary outcome measure)

Locations
United States, Vermont
Substance Abuse Treatment Center, University of Vermont Recruiting
Burlington, Vermont, United States, 05401
Contact: Stacey C. Sigmon, Ph.D. 802-656-9987 [email protected]
Principal Investigator: Stacey C. Sigmon, Ph.D.

http://clinicaltrials.gov/ct2/show/NCT00719095
 
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I am glad to hear of this study. I wanted to post the link to www.harmreduction.org , as well as www.viennadeclaration.com but was not sure where to post. These sites both offer information and opportunity to actively promote safe drug use, Prescription as well as 'street drug' use. I personally am not in favor of any drug use as my son, David, died in August 2009 from a prescription Opiod pain medication, Narcan was not, and still is not, prescribed here in Florida along with Opiate pain medication, as it should be prescribed. Sorry if I posted in the wrong place.....'for David'...Phreexmom
 
Going by her suggested completion date, it seems these studies are likely to have concluded, so I did a little digging..

I've found the following paper published that seems to be the result of this study:
http://www.ncbi.nlm.nih.gov/pubmed/22404717

I've also found the following papers that may or may not be in some way related to the study, and focus on a similar theme, which the same researcher was involved in:
http://www.ncbi.nlm.nih.gov/pubmed/21741781
http://www.ncbi.nlm.nih.gov/pubmed/19081679

There are some other related publications by the researcher available here :)
 
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CONCLUSION:

Among the current detoxification regimens, the available clinical and scientific data suggest that the best approach may be using an initial 2-4 mg dose of buprenorphine combined with clonidine, other ancillary medications, and progressively increasing doses of oral naltrexone over 3-5 days up to the target dose of naltrexone. However, more research is needed to empirically validate the best approach for making this transition

Color me suspect. :(
 
Thats really good though that this is going on. Many need help with opioid addictions.
I used to be one and good to see some people are getting helped out/available for treatments.
 
Phreexmom said:
I am glad to hear of this study. I wanted to post the link to www.harmreduction.org , as well as www.viennadeclaration.com but was not sure where to post. These sites both offer information and opportunity to actively promote safe drug use, Prescription as well as 'street drug' use. I personally am not in favor of any drug use as my son, David, died in August 2009 from a prescription Opiod pain medication, Narcan was not, and still is not, prescribed here in Florida along with Opiate pain medication, as it should be prescribed. Sorry if I posted in the wrong place.....'for David'...Phreexmom
Click to expand...

I'm prescribed naloxone, even though I'm no longer using heroin. I do live in Los Angeles though.

Hopefully they'll increase the amount of doctors prescribing naloxone to opiate users.
 
Naltrexone has also been used in alcohol and nicotine addiction.
 
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