Opioids Beta Endorphin Deficiency (srs)

[xks202]

I have to replace all of my pituitary hormones due to a head injury which destroyed its function. The pituitary makes beta endorphin. I have confirmed total pituitary dysfunction. Something like naltrexone would do nothing for me. Without vicodin or some opiate I have no desire to get out of bed.

Could anyone extrapolate on possibly the best long term opiate replacement therapy for such a situation? I do not have experience in that realm and my endocrinologists do not seem to care.

 

[sekio]

B-endorphin is made by more than just the pituitary.

As for opioid replacement therapy, whatever works. But you'll probably have a hard time finding doctors that will prescribe you opioids the rest of your life.

 

[movbikwaet]

Try effexor, it has some opiod activity and you shouldnt have a problem getting it.

 

[xks202]

Thanks. Could you tell me where else beta endorphin is made? Isn't the majority of it made in the pituitary?

 

[Smokey McPot]

if you cant get anything from the doctors in terms of opiates theres always methadone

 

[sekio]

Endorphin is also released by the hypothalamus. Also, endorphin is not the only opioid peptide - there are some that are derived from e.g. milk and bread, and are seen in the gut (e.g. caseomorphin)