• N&PD Moderators: Skorpio

Best compound to abort an LSD experience

Aborting trips is stupid you will deal with it the rest of your life instead of a few hours.
If you are really that pathetic try a single pane window that’s what the CIA used.
 
Seroquel will kill a trip and then put you to sleep. Not a bad idea if you're having a completely miserable trip.
 
Lucytaak: This thread is about which compound is best to abort a trip, not whether aborting the trip is a good idea or not. I have made a temporary thread where you can argue this out to your hearts content.

I have culled part of this thread that was going way off topic.

Dr Beat your post is only soft deleted, and could be restored if you want.


Please don't feed trolls.

V
 
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Reminisant B said:
Would be interesting to know the effects - am talking about purely 5ht2a - most atypical anti-psychotics also antagonise D2 receptors. The other ones I can think of have other non-5ht2a effects as well - mirtazapine, trazadone(?)


A good bit of research is pointing towards schizophrenic states being caused by dopamine imbalances. An antipsychotic that antagonizes D2 is probably a good trait while trying to abort a trip that is causing severe psychological damage and psychotic states. But I agree that it would be interesting to explore other alternatives.

This is just a personal theory but I believe LSD has such a high likelihood of causing psychological problems (in comparison to other hallucinogens) because of its potent agonism of D2 receptors (plus it is just such a promiscuous neuromodulator).
 
Just adding my two sense, as other people seem to be thoroughly covering the antipsychotic/5-HT2A antagonist side.

Benzos for aborting a trip. On a far to intense DOI trip (that shit is strong), I took increasing doses of diazepam and lorazepam up to doses that would have normally knocked me out. I felt nothing from them. (15mg Diazepam and 7mg Lorazepam). I took 7.5mg zopiclone, and I was fixed. I was still tripping, i.e. visuals. But I could handle it 10x better.

Conclusion, Zopiclone is a better trip aborter (abortofectant) than Diazepam or Lorazepam
 
^ Strage you mention that, I would have to agree zopiclone effects are definately different from traditional benzos.

Zopiclone always felt like it had some kind of unique effect on 5HT or definately an effect above and beyond traditional benzodiazepines.

*On searching for this it appears the differences might be its selectivity for different benzo receptor subtypes. Someone might know more info on this, I find benzo subtype receptors very complicated.
 
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As already mentioned, risperidone WILL bring you down to Earth extremely fast as it's one of the most powerful 5HT2a antagonists out there.

BUT, like zyprexa and other powerful antipsychotics, risperidone can have very nasty side-effects in certain people.

If you want a reliable and somewhat 'safe' trip aborter, figure out which 5HT2a antagonists you could feasibly get your hands on. Then read their usage and precautions guidelines on RXlist.com

If possible, go with one whose side effects tend to plague people with different existing conditions to yourself
 
As fastandbulbous mentioned chlorpromazine is quite effective, but it's also hard to obtain.
There are some easier ways like intramuscularly administrated niacin (vitamin B).
 
IMHO, those who choose to take a neuroleptic (ie zyprexa) to abort a trip have virtually NOTHING to worry about as far as side-effects; only those who take these drugs on a regular basis should be concerned. Everyone needs to chill-out worrying about 'tardive diskinesia' and the like from short-term use; these are things that happen to people who are prescribed hefty amounts over periods of years.

My best guess tells me that the damage done by enduring a psychotic episode on LSD, psilocybin, mescaline, etc. would be much more devestating to your mind/body than the one-time use of seroquel to kill it in it's tracks.
 
who is going to IM niacin while undergoing a psychotic reaction?

FWIW, respiridone has just been approved by the FDA for use in schizophrenic and bipolar children, so it should be easier to find now! (joke)
 
Reminisant B mentioned trazodone and mirtazapine -- I have used (separately) both Risperidone .375mg and mirtazapine 15mg to abort trips. I prefered mirtazapine because it is more relaxing & closer to a silent neutral 5ht2a antagonist - while risperidone an inverse 5ht2a agonist causes insane hyperdimensional psychedelic dreams- fun on any other night.

I imagine nefazodone a well known and more potent 5ht2a antagonist (not an entirely silent one) analogue of trazodone would work well too.
Mianserin should work fine too.

As far as tardive dykinesia etc -- tardive means slow in appearance/onset (months/years.) You are at risk albeit - lower than avg. of developing dyskinesias and dystonias when taking old antipsychotics(5ht2a Antagonists confer antidyskinetic fx) - dystonic reactions are most common around 14-22y/o males. These are also more common when used with dopaminergic drugs amphetamine, cocaine et al. Benadryl is of course an easy remedy.
 
"you eat all this acid? man you better hope to god ther's some damn thorazine in that bag or your fucked!"

i'll take hunter's word that thorazine is probably the best
 
oh also i've heard dramamine works but that sounds like bullshit to me, kinda seems like it would make it worse seeing as how it's a deliriant.
 
I haven't seen this mentioned yet. One night, while tripping (on LSD), a friend and I took some Zoloft just to see what would happen. 45min after taking the Zoloft, our trip basically ended; all visuals disappeared, and the mental state all but disappeared as well (some mild "trippiness" remained, but it was like reducing the trip by like 95% ). I was wondering if any of you that regularly post in this forum would have an answer as to why this happened. I'm no chemist, nor do I have any medical background other than what I have read, so if anyone with a much more expansive background could shed some light on this for me, I would appreciate it. :)
 
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