fastandbulbous
Bluelight Crew
Well when I found out that someone had died from IVing mxe, it left a really horrible taste in my mouth. Comments about they would have killed themselves anyway, with something else, doesn't really help.
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N&PD Moderators: Skorpio | someguyontheinternet
Banning non-chemists from starting threads
- Thread starter Fertile
- Start date
Fertile
Bluelighter
- Joined
- Mar 31, 2022
- Messages
- 1,627
I know how you feel. U-47700 was intended to be pilled & put in patient packs. Someone sold powder... and I feel guilty 10 years on.
paracelsius
Bluelighter
- Joined
- Mar 11, 2020
- Messages
- 197
I dont know about banning anybody from posting thread on BL. But it is sure is a good idea to ban discussing synth details because ppl who are not chemist might not be aware how dangerous some reactions/reagents are.
I mean in another forum, I once saw some kid asking questions about somewhere he reads on how to make cyanogen bromide from cyanide and bromine so he can "cook" MARs probably at home...Jeeeesus!.Lord have mercy! Obviously not a chemist and has absolutely no idea wtf he's talking about. I mean cyanogen bromide is as nasty a chemical as it gets, LETHAL by inhalation or contact and so is bromine so is cyanide! To make matter worse, cyanogen bromide reacts violently (no, explosively!) with water to release another lethal substance hydrogen cyanide gas. A tragedy waiting to happen!!! kuddo to BL on banning synth chem talk....yo'all stay safe
I mean in another forum, I once saw some kid asking questions about somewhere he reads on how to make cyanogen bromide from cyanide and bromine so he can "cook" MARs probably at home...Jeeeesus!.Lord have mercy! Obviously not a chemist and has absolutely no idea wtf he's talking about. I mean cyanogen bromide is as nasty a chemical as it gets, LETHAL by inhalation or contact and so is bromine so is cyanide! To make matter worse, cyanogen bromide reacts violently (no, explosively!) with water to release another lethal substance hydrogen cyanide gas. A tragedy waiting to happen!!! kuddo to BL on banning synth chem talk....yo'all stay safe
F.U.B.A.R.
Bluelight Crew
You can't be responsible for the stupidity of others mate. Every innovation in history has been the cause of death for some...
Fertile
Bluelighter
- Joined
- Mar 31, 2022
- Messages
- 1,627
Yeah - but if YOU hadn't done what you did... they might still be alive. Trust me, I've been through it, It get's no easier. You add an extra magnitude to the acceptable TI of anything else you might do... and you worry.
realgar
Bluelighter
- Joined
- Jan 22, 2007
- Messages
- 45
Actually, it doesn't. Cyanogen bromide slowly hydrolyses to give cyanate, not cyanide ( https://sci-hub.se/10.1139/cjr49b-029 ). You can prepare a stock solution of BrCN in acetonitrile and use it e.g. for activation of agarose suspended in an aqueous buffer solution to prepare sorbents for affinity chromatography. ( https://sci-hub.se/10.1016/s0021-9673(00)90957-9 ) My colleagues did that last summer.
Fertile
Bluelighter
- Joined
- Mar 31, 2022
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- 1,627
Hydrolysis?
That would be to CO2 + NH4Br.
In alkali media you get OCN- + Cl- + H2O.
So yes, NaOH will destroy excess NaOH your freebase will form a nice layer.
Also yes to obviously you get it into your solvent as soon as you can. Obtaining BrCN, now there's a fun thing. It's listed as a chemical weapon...
That would be to CO2 + NH4Br.
In alkali media you get OCN- + Cl- + H2O.
So yes, NaOH will destroy excess NaOH your freebase will form a nice layer.
Also yes to obviously you get it into your solvent as soon as you can. Obtaining BrCN, now there's a fun thing. It's listed as a chemical weapon...
thegreenhand
Bluelight Crew
i've thought about this issue quite a bit. i will say this: everyone should know that we have been discussing the problem for some time now. unfortunately, a simple solution has eluded us thus far.
one proposal that i personally favor is offering verification of qualifications. we could add this to your profile much in the way that us mods have titles under ours. idk the exact details of how it'd be done, but you get the idea. of course, this would all be entirely voluntary. i completely understand having privacy concerns.
that said, other non-qualified people should still absolutely be allowed to post threads. many times newbs have asked great questions that stimulated thoughtful discussion. i sincerely want to avoid NPD becoming a 'clique' of subject matter experts who only talk amongst themselves. education has always been a part of bluelight's purpose.
i also take issue with restricting the proposal to just chemists. not everyone here is a chemist or aspires to be. drugs can be studied through many other lenses. our subforum name is neuroscience & pharmacology discussion for a reason. i think any given STEM field can have applications to psychoactive drugs. neuroscience is a fundamentally interdisciplinary science. why limit ourselves to chemistry ?
i suppose the tl;dr is as follows - we are aware of the content quality issues, but we don't want to rush a quick fix. this sort of community feedback is essential to us forming a well crafted solution, and i'm glad the issue has been raised.
apologies for being late to this thread.
one proposal that i personally favor is offering verification of qualifications. we could add this to your profile much in the way that us mods have titles under ours. idk the exact details of how it'd be done, but you get the idea. of course, this would all be entirely voluntary. i completely understand having privacy concerns.
that said, other non-qualified people should still absolutely be allowed to post threads. many times newbs have asked great questions that stimulated thoughtful discussion. i sincerely want to avoid NPD becoming a 'clique' of subject matter experts who only talk amongst themselves. education has always been a part of bluelight's purpose.
i also take issue with restricting the proposal to just chemists. not everyone here is a chemist or aspires to be. drugs can be studied through many other lenses. our subforum name is neuroscience & pharmacology discussion for a reason. i think any given STEM field can have applications to psychoactive drugs. neuroscience is a fundamentally interdisciplinary science. why limit ourselves to chemistry ?
i suppose the tl;dr is as follows - we are aware of the content quality issues, but we don't want to rush a quick fix. this sort of community feedback is essential to us forming a well crafted solution, and i'm glad the issue has been raised.
apologies for being late to this thread.
I am currently triaging molecules without rationale/series of molecules into the Dresden chemical fluff thread.
Until official policy is decided on (as thegreenhand pointed out, we aim to keep a balance of allowing all to post without it becoming an abstract art show).
When posting molecules, the more you can justify them, the more likely a thread will remain stand-alone. The chemical fluff thread is not a free for all, and discussion is still encouraged there, but until changes are made it will be held to a lighter editorial standard.
Until official policy is decided on (as thegreenhand pointed out, we aim to keep a balance of allowing all to post without it becoming an abstract art show).
When posting molecules, the more you can justify them, the more likely a thread will remain stand-alone. The chemical fluff thread is not a free for all, and discussion is still encouraged there, but until changes are made it will be held to a lighter editorial standard.
paracelsius
Bluelighter
- Joined
- Mar 11, 2020
- Messages
- 197
Where you get that? check your basic chemistry again:
Cyanogen bromide is hydrolyzed to release hydrogen cyanide and hypobromous acid thus:
BrCN + H2O ---> HCN + HOBr
Note that deactivation of BrCN is extremely exothermic and may be explosive (just cf all the refs on the stuff cited on wiki or better yet just get the MSDS.
Since you referring to agarose or affinity chromatography, I gather you or your buddy are biochemists dealing in mg of the stuff safely dissolved in a solvent in a proper lab under a proper hood. Not kilo scale or in your kitchen, am I right? I was just warning about a kid I once saw trying to make the stuff from other nasty chemicals (Bromine and Cyanide!!) in his kitchen so he can make 4-MAR. Not like you or your buddy who know what you doing!
Anyway not arguing or anything just warning regarding ppl with no chemistry training handling dangerous chemicals!
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plumbus-nine
Bluelighter
I voted for yes even though I probably wouldn't pass a chemistry exam, forgot too much of the basics over all the years since high school. (Passed the test for advanced customers in more than one shop though but they aren't serious about these tests as they will know just too good that it's all just a big lie). But I heard that in other times here was more activity and more high-quality discussion which I'd like to see to return.
the product depends very strongly on pH
cyanide plus hypochlorite or hypobromite in strongly basic solution gives cyanate then hypochlorite further degrades the formed cyanate into Nitrogen CO2 and water. Bleach is a standard way to kill aqueous cyanide, though there are better ways.
if the pH is below 3 then very little hydrolysis of BrCN happens and indeed cyanogen bromide can be made from aq cyanide and bromine, at acid and neutral to mildly basic pH 8-9 the product BrCN is pulled into a water immiscible solvent like toluene
variations include using aquesous hypochlorite, bromide and cyanide and buffer.
the observation I make here is most of the people strutting calling for exclusivity and censoship around this sub forum are not real chemists at all.
as pedantic as ever piglet.
the product of the initial hydrolysis is hypobromite which you would know if you had actually comprehended what I wrote.
I will leave it there
have a nice life
I am not chemist but
wow much ragequit
4meSM
Bluelighter
I voted no but there should probably be some kind of disclaimer on the “name a molecule” thread, just so that people know that many of those compounds are just random derivatives with no real science behind them.
As others have said, threads with impossible molecules, psychotic rants and other nonsensical stuff should be closed or moved somewhere else.
Though I think the mods have been doing a pretty good job.
As others have said, threads with impossible molecules, psychotic rants and other nonsensical stuff should be closed or moved somewhere else.
Though I think the mods have been doing a pretty good job.