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Baclofen, diazepam and amitriptyline for alcoholism

BellaCJ

Greenlighter
Joined
Oct 31, 2014
Messages
4
I've been taking baclofen for alcoholism for over a year now. My dose went from 30 mg all the way up to 210mg. At the high dosage I had severe insomnia and it resulted in massive anxiety attacks. My doctor perscribed me amitriptyline for sleep and it worked well at first. I was on 150mg of amitriptyline at night and dropped the baclofen dose from 150mg + to 137.5 mg. This worked for about 3 weeks until i had another massive anxiety attack. I realised that there was a build up of amytriptyline and my body could not tolerate it. So I spoke to my doctor and reduced the dose to 75mg a night. It worked for 2 weeks and then another 2 massive anxiety attacks occurred. It was a horrible chemical anxiety that felt like every nerve was heightened along with sever insomnia,:! my body's homeostasis was out of balance again. I spoke to my doctor again and reduced amitriptyline again to 50mg a night. Then to prevent the anxiety attacks from a build up I would have 2 break days from endep and would suffer anxiety on those days and starting up the amitriptyline again. I have suffered from anxiety for years and drinking was the only solution to the point where my ggt liver enzyme level went up to 444 and the average is 31, i am 8 months sober now but the chemical up and downs have been a hard journey. My doctor prescribed me diazepam 1 to 2 mg for the anxiety days and it worked but now my body is building a slight tolerance. I tried to cut down the baclofen from 137.5 to 131 and that was fine but I thought i could increase amitriptyline again but that didn't work and i suffered insomnia and anxiety again. Now the dose of diazepam has increased from 0.5 mg to 3mg. I tried to reduce baclofen to 125mg so 12.5 mg in a week and it gave me more anxiety, So now i'm on 131mg baclofen 50mg amitriptyline and 2.5 -3 mg valium a day. I read that valium being a gaba a agonist does not help with withdrawal from baclofen. I want to cut down further on baclofen. All these other posts about pregablin seem to dicuss another addiction. The baclofen and amitriptyline work well together after a few days of having the doasge and prevent anxiety and allow sleep as amitriptyline stops the insomnia side effect of baclofen, however a build up of amitryptyline makes it intolerable and the break days end up counteracting the good anti anxiety days. Otherwise baclofen and amitriptyline are a good combination for addiction and anxiety. Any ideas on how to combat baclofen reduction?:)
 
Wow. Spinning plates, spinning plates, and if one drops, right?

As someone familiar with polydrug tapering ( taper-plateau-taper-relapse-start all over again tapering) I can sympathize with your struggle.

I think at a certain point for us, and you seem to be farther down the sober-ish :) road than I...we just have to resign ourselves to a bit if suffering. Any new substance to ease the pain may just present another outlet for that Thing inside that wants Total Peace.

If that makes any sense?
Anyways, don't know your whole 'anxiety' timeline, but one note of possible help may be Naltrexone. I was in a study for alcoholism, many years ago, and far from making the pain go away it makes you feel right like shit. Lol. But, not *that* bad, not anxious (for me at least) an it certainly stopped me from wanting a drink. Or a cigarette! (Would have dry heaves at the lingering smell of tobacco, and oddly enough, any cigarette tasted like the very first one. Basically, like ass! You know how after smoking awhile you don't even 'taste' it?)

Anyways, maybe ask yr doc about Naltrexone?
Wikipedia has an article, though I can't seem to post it here for some reason. I'm limited to smartphone, unfortunately.

So...
I wish you the best.
 
You are right spinning plates..its all a trial and error. The anxiety is a horrible companion, i used to be pill and addiction free and have let it spiral over the years due to circumstances. I looked up baclofen and it was the only thing that has helped, AA is a load of crap and made me feel like shit as the people there were so depressive. Are you also dealing with the alcoholism?. Did naltrexone cure any preexisting anxiety? I still smoke and that i don't want to quit.
 
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