I've been taking baclofen for alcoholism for over a year now. My dose went from 30 mg all the way up to 210mg. At the high dosage I had severe insomnia and it resulted in massive anxiety attacks. My doctor perscribed me amitriptyline for sleep and it worked well at first. I was on 150mg of amitriptyline at night and dropped the baclofen dose from 150mg + to 137.5 mg. This worked for about 3 weeks until i had another massive anxiety attack. I realised that there was a build up of amytriptyline and my body could not tolerate it. So I spoke to my doctor and reduced the dose to 75mg a night. It worked for 2 weeks and then another 2 massive anxiety attacks occurred. It was a horrible chemical anxiety that felt like every nerve was heightened along with sever insomnia,
my body's homeostasis was out of balance again. I spoke to my doctor again and reduced amitriptyline again to 50mg a night. Then to prevent the anxiety attacks from a build up I would have 2 break days from endep and would suffer anxiety on those days and starting up the amitriptyline again. I have suffered from anxiety for years and drinking was the only solution to the point where my ggt liver enzyme level went up to 444 and the average is 31, i am 8 months sober now but the chemical up and downs have been a hard journey. My doctor prescribed me diazepam 1 to 2 mg for the anxiety days and it worked but now my body is building a slight tolerance. I tried to cut down the baclofen from 137.5 to 131 and that was fine but I thought i could increase amitriptyline again but that didn't work and i suffered insomnia and anxiety again. Now the dose of diazepam has increased from 0.5 mg to 3mg. I tried to reduce baclofen to 125mg so 12.5 mg in a week and it gave me more anxiety, So now i'm on 131mg baclofen 50mg amitriptyline and 2.5 -3 mg valium a day. I read that valium being a gaba a agonist does not help with withdrawal from baclofen. I want to cut down further on baclofen. All these other posts about pregablin seem to dicuss another addiction. The baclofen and amitriptyline work well together after a few days of having the doasge and prevent anxiety and allow sleep as amitriptyline stops the insomnia side effect of baclofen, however a build up of amitryptyline makes it intolerable and the break days end up counteracting the good anti anxiety days. Otherwise baclofen and amitriptyline are a good combination for addiction and anxiety. Any ideas on how to combat baclofen reduction?

