4DQSAR
Bluelighter
- Joined
- Feb 3, 2025
- Messages
- 5,498
BTW I hate to just say to people 'Oh, I saw something like this in a paper' because let's honest, it's hardly proof. Anyway, I have gone the extra mile to provide reference:
- Novel phencyclidine derivatives, preparation methods and pharmaceutical compositions containing same
Publication Number: CA-2292642-A1
Priority Date: 1997-06-03 - Novel phencyclidine derivatives, preparation methods and pharmaceutical compositions containing same
Publication Number: EP-0986555-A1
Priority Date: 1997-06-03 - Novel phencyclidine derivative, method for producing the same, and pharmaceutical composition containing the same
Publication Number: JP-2002502411-A
Priority Date: 1997-06-03 - Novel phencyclidine derivatives, preparation methods and pharmaceutical compositions containing same
Publication Number: WO-9855478-A1
Priority Date: 1997-06-03 - Phencyclidine derivatives, preparation method and pharmaceutical compositions containing same
Publication Number: US-6342511-B1
Priority Date: 1977-06-03
Grant Date: 2002-01-29
It's become apparent that one 'Jean-Marc Kamenka' spent a good three decades looking at the QSAR or arylcyclohexylamines, their homologues and their derivatives. So before the patents were a series of academic papers:
I have limited myself to papers written in English and given that BTCP briefly turned up in fake pills (it being a pure DRI), I haven't included EVERY paper on that specific chemical as while it was well wothwhile investigating, we now know it has no obvious use case.
I wonder if someone more skilled in the use of Chatbots could use the above to train one to predict the activity of compounds that thusfar have not been synthesized. Or to write ACAihKAL or whatever title you decide to go with.
