DJDannyUhOh,
Originally posted by DJDannyUhOh
3,4-Methylenedioxymethamphetamine significantly inhibits the magnesium channels that are required to relax smooth muscle. Here's the link.
http://303.ubik.to/e4xapp.htm
Absolutely nothing (none of the musculature references) on that page relates to our discussion.
Bad harm reduction information is as bad as no harm reduction information. It lowers the standards of truth, and ends up creating a population of people who are skeptical and who may not follow the legitimate harm reduction information due to the "signal to noise" ratio. Case in point, if the NIDA issued an adverisy which was truthful and accurate no one would follow it because the NIDA has published (goal oriented) misinformation in the past.
You "feel" convinced that there is "something wrong" with the MDMA + Viagra mix. That is your right. It is your right to avoid mixing the two drugs. You even have the right to recommend that people stay away from the drug mix because
you feel in
your opinion that it
may be harmful. But it is not your right to knowingly inject that
opinion masquerading as a
knowledgable resource simply because you "think" everyone should stay away from it because you "feel" that you are right. At best, it is misguided (opinions are like assholes...). At worst, it is manipulation (which is what people like Recardi and the NIDA has been doing all along for their own goal oriented purposes).
We try our very best to provide the most scientifically accurate information which is available. Thus far, there is no compelling reliable scientific evidence available indicating that taking MDMA with Viagra is harmful EXCEPT where someone has a pre-existing heart condition.
I would like to point out something else, and this is purely my opinion based on observation. There are many drugs which someone could mix with MDMA which are over the counter. We never hear of anyone speculating that Advil may be a harmful mix, nor asprin, nor anti-histamines (people do ask questions, but the answers are not "pounced on"). Yet, when the subject ventures into the realm of sexuality, all of a sudden there are a plethora of nay sayers, all holding a "gut level" opinion, but baring no reliable scientific facts to support their assertions. As soon as you incorporate sexuality with drugs, there appears to be far more "advised caution" than with pretty much any other activity or or drug mixture (remember, I am talking about "peanut gallery" opinions, not those dealing with sound scientific information). Rather than revealing my theory as to why exactly this is, I leave it up to everyone else to draw their own conclusions...
Originally posted by DJDannyUhOh
Let me put it this way. I've exhausted my interest on this post. My main objective was to give a little thought into mixing E with viagra. I'll be the first to admit that my references or any others that anyone else might give will not be 100% proven on this issue, but they damn sure make a case for putting at least some consideration into mixing such drugs together. Until a study is sanctioned by the AMA or WHO, we cannot assume an E and viagra cocktail is safe in one aspect or another. If you want to defend the "Yeah, E and viagra are OK for me and they make me fuck like a bunny" point of view, by all means go ahead. Just realize this is not the most healthy point of view and it should be analyzed as closely as any other point of view. I'd rather error on the side of caution, especially if I were up in age. Just remember that there is a point where everything will catch up with us and that there is no way to tell how any drug will react with any of us, and ultimately the decision comes down to the individual.
We all know that the internet is sketchy with details at best. If you really want the "nitty gritty" of cutting edge medical research, go to your local university that has a pre-med curriculum. Usually, colleges of this type have a library of health sciences, i.e. University of Illinois at Chicago. (where I went) Here you will find the most recent studies that haven't made their way to the internet yet. Most of it will be found in issues of JAMA. (Journal Of The American Medical Association)
Many people on this site have a "soap box" stance on certain issues and it becomes no more conclusive that debating religious issues. Quote this post to your heart's content. I am no more opinionated than anyone else on this subject and I know no matter what, your opinions will seem to supersede mine, so for the sake of a long and drawn out thread, I graciously concede the final word to you.
The internet is sketchy ONLY if you rely on the fringe publishing. There are
many medical and scientific databases which are anything but "sketchy." Making an assertion without a shread of supporting evidence, and then suggesting to "go fish" for the evidence is more an attempt at "winning" an argument, than establishing a scientific truth (whether it is an "absolute" scientific truth, or one which is based on "current" knowledge and is subject to change).
You initially proposed a detailed biochemical process which occurs. But when asked for details you respond with
"the answer is out there" (
excerpt from: The X-Files 
). I've worked with physicians and biomedical researchers for most of my professional life. And, quite frankly, your approach to this whole issue has made me question your having ever attended medical school. You don't seem to know where to look (the internet is a marvelous scientific and medical research tool - something that is NOT lost on a third year medical student), and your argument breaks down (and you become angry) when asked for simple references to validate your assertions. I'm sorry, but this this is simply NOT how information is disseminated in the medical community.
Here is what I said in the beginning of this discussion. It appears to have come full circle:
http://www.bluelight.ru/vb/showthread.php?postid=1776185#post1776185
Originally posted by Brian Oblivion
Look, I'm not trying to flame you, so please don't take what I am saying that way. A lot of what you are saying is purely your opinion, but you are speaking as though it is factual information. There is a wide gap between educated "factual" information, and drawing conclusions simply because they "seem right" to you. Too much of the "common knowledge" in the drug community is based on somebody else's "seem right" logic that has no basis in real fact. Drawing your own conclusions and treating them as scientific fact does a disservice to everyone in this community.
Brian