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Misc Any experiences with Modafinil? Particularly Modafinil vs Adderall??

Oxy8_8

Bluelighter
Joined
Apr 24, 2013
Messages
489
Location
England
I'm big-time into prescription medications, whether I abuse them or not (most I am prescribed, the exception being I continued Xanax after my refills were stopped (I still need it and it treats my anxiety and panic attacks excellently. I still only take 0.5-1mg per dose).
Namely:

Sertraline (Zoloft) 100mg daily ---never abused (for "Severe Major Depressive Disorder w/ psychotic features" and related mixed anxiety-depression)

Lamotrigine 25mg twice daily --- never abused (as a mood stabilizer, minor anti-depressant, and weak anti-psychotic)

Promethazine Hydrochloride 100-200mg throughout the day --- somewhat abused (taken for the infamous "opi-itch" and to potentiate my opiates. Also good for nausea. Excellent for a lot of opiate WD symptoms for those rare "shit-I-ran-out-early" moments, great for my Hay Fever allergies, good for anxiety and good for insomnia)

OC OxyContins and oxycodone instant release capsules --- abused, but recently reduced from 300mg/day to 100-200mg/day lately (taken for severe chronic pain due to severe acute pancreatitis and rhumatoid arthritis)

Methadone 35mg daily --- never abused, taken to help keep control of my dosage of Oxy (my doctor thought my dosage was getting too high, I mostly disagree. I am in daily INTENSE AGONY) and also to help with pain-management. Only taking to keep my doctor happy. Planning to get off this ASAP (either persuade them to move me onto a fentanyl patch or something else similar instead, or wean myself off by myself and I guess sell it or something.

Alprazolam (Xanax) 0.5mg-1mg four times daily ---- sometimes abused, not often, never high levels, usually I genuinely need 2-3mg per 24hr period (as a muscle relaxant to help with my rheumatoid, but mainly for coping with my crippling anxiety and panic attacks)

I find I get excessively drowsy/tired during the day (I know, not a surprise given my list of meds) but I have had like chronic fatigue my whole life. Never any energy or wakefulness. It's annoying. My doctor said I seemed to be stuck somewhere between Chronic Fatigue Syndrome and Narcolepsy without quite having either lol.

Anyway (NO LECTURES PLEASE), I have been considering trying Adderall. After much research and thinking, I have decided this is something I definitely want to do. Only at low doses and definitely not daily, just when I really need the energy or to be alert or concentrate. I'm reading the Game of Thrones series of books right now and love love love them. I used to be able to sit and read for several hours but now, just 15 minutes has my eyes swimming and me almost nodding (even at low doses of the above meds).

It's really getting me down and Adderall seems the best "upper" for me after thoroughly researching them all and not wanting one too extreme, or a non pharmaceutical (like cocaine cut with rat poison and god-knows-what or crystal meth made in some guys basement with battery acid)...until I came across the Modafinil. Anyone on it or been on it??

It is described as a "wakefulness promoting agent" rather than a classic amphetamine-like stimulant.

http://en.wikipedia.org/wiki/Modafinil

What do you guys think? I want to be careful due to my tendencies toward anxiety (although if needed, I always have Xanax around to "undo" the anxiety/stimulant). Which med sounds better for a first-timer?
 
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ummmm you are on a bunch of drugs that are metabolized through cytochrome 450 3A4 enzyme, and in my experience, modafinil is a potent inducer of 3A4. it cut the duration of klonopin in half for me, instead of feeling the kpin for 12hrs, it only lasted 6hrs.

namely, this is going to be a problem with your methadone, oxy, and xanax. you will have to dose much more often and it will not be fun. id suspect modafinil to decrease the duration of oxy to less than 2hrs, and the duration of methadone to 8hrs. this is not something you want. and the xanax would last like 45-60MINUTES

modafinil isnt a bad substance, it did what it is supposed to do, that is make you feel more awake. however, i didnt feel it ws much stronger than a large dose of caffeine. ii liked it because im on bupre and modafinil inc the levels of norbup in my system.

stay away from modafinil; you iwill be sorry if you take the script. trust me, the 1st dose you will notice a major difference in how long your other meds last...

try some redbull or 5hr energy first. you dont need more meds, you need less.

you cant expect to be all that awake and alert on methadone, oxy, xanax AND promethazine. promethazine is my fav antihistamine because it is more sedative than hydroxyzine and dph combined. if i take 12.5mgs promethazine on my bupre, i will be nodding in no time. i even tried to take 60mgs of vyvanse to turn the tables, and i still nodded out hardcore on the prometh. id suggest switching to hydroxyzine which is much less sedative. even if you get an adderall script you will still be falling asleep oon the promethazine in my experience. it doesnt matter...
 
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ummmm you are on a bunch of drugs that are metabolized through cytochrome 450 3A4 enzyme, and in my experience, modafinil is a potent inducer of 3A4. it cut the duration of klonopin in half for me, instead of feeling the kpin for 12hrs, it only lasted 6hrs.

namely, this is going to be a problem with your methadone, oxy, and xanax. you will have to dose much more often and it will not be fun. id suspect modafinil to decrease the duration of oxy to less than 2hrs, and the duration of methadone to 8hrs. this is not something you want.

DEFINITELY NO MODAFINIL FOR ME!!!! LOL.
Would I be okay with Adderall? I've never in my life done an upper but feel I really want, almost need to now. How about Adderall? Would that mess up any of the meds I take? If not, just general amphetamines? (I'd much rather it be a prescription-drug, though.
 
I find Nuvigil to last longer then provigil. It def keeps you awake at with the right dose it can cause a great sense of well being for some time. No harsh comedown or bad side effects with traditional stims.

No idea why so many people harp on nor bupe. If it actually crossed the BBB better, out competed bupe I'd doubt we would have a ORT med. it(nor bupe)works mostly in the gut and lungs. It would be a highly unpleasant opioid and prob quite deadly.
Nor bupe is not a substance that you want more of.
 
DEFINITELY NO MODAFINIL FOR ME!!!! LOL.
Would I be okay with Adderall? I've never in my life done an upper but feel I really want, almost need to now. How about Adderall? Would that mess up any of the meds I take? If not, just general amphetamines? (I'd much rather it be a prescription-drug, though.


are you shitting me man??? you take 100-200mg promethazine a day? am i reading that right??? i can barely keep my head up on 12.5mg, on 25mg im in complete nodd mode. seriously, this shit is strong.

good luck getting an adderall or amphetamine script for "wakefullness" lool. why do you want adderall? have you spken to your doc about this yet?? what do you think it will do for you?

no it wouldnt be particularly dangerous with any of the meds, im not sure about lamotgrine or however the fuck you spell it lol...
 
ummmm you are on a bunch of drugs that are metabolized through cytochrome 450 3A4 enzyme, and in my experience, modafinil is a potent inducer of 3A4. it cut the duration of klonopin in half for me, instead of feeling the kpin for 12hrs, it only lasted 6hrs.

namely, this is going to be a problem with your methadone, oxy, and xanax. you will have to dose much more often and it will not be fun. id suspect modafinil to decrease the duration of oxy to less than 2hrs, and the duration of methadone to 8hrs. this is not something you want. and the xanax would last like 45-60MINUTES

modafinil isnt a bad substance, it did what it is supposed to do, that is make you feel more awake. however, i didnt feel it ws much stronger than a large dose of caffeine. ii liked it because im on bupre and modafinil inc the levels of norbup in my system.

stay away from modafinil; you iwill be sorry if you take the script. trust me, the 1st dose you will notice a major difference in how long your other meds last...

try some redbull or 5hr energy first. you dont need more meds, you need less.

you cant expect to be all that awake and alert on methadone, oxy, xanax AND promethazine. promethazine is my fav antihistamine because it is more sedative than hydroxyzine and dph combined. if i take 12.5mgs promethazine on my bupre, i will be nodding in no time. i even tried to take 60mgs of vyvanse to turn the tables, and i still nodded out hardcore on the prometh. id suggest switching to hydroxyzine which is much less sedative. even if you get an adderall script you will still be falling asleep oon the promethazine in my experience. it doesnt matter...

I take the promethazine at night. The Oxy doesn't make me tired in the way codeine or morphine do, it actually gives you a boost for a couple of hours. The Xanax doesn't make me like it does when it's abused. I takes away my feelings of nervousness or panic and replaces it with a calm, at ease (if a little sleepy).

I did say please please no lectures on how I'm on too much etc? I'm very very sick both Physically end mentally and need a lot of medication.

Maybe I should have looked for the amphetamine megathead or something haha.
 
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didnt read about the promethazine at night, im not lecturing im simply trying to get a perspective.

you ask me for my opinion, and then when i give it, you disre, gard any input i try to give??? dont use the sick card please, because it doesnt really seem like you are doing anything to get better. you are not a wounded gazelle in the plains of south africa, you are a human. you can fight, you need to fight.

i didnt comment on anything about your other meds dude, not even about the opiates and benzos. the only thing i said is that you cant expect to feel awake when you take that much promethazine "during the day"


i hate when my mother tells me im on too many meds, like how does she know? she doesnt, so i cant say how much is too much for you.

you asked if adderall is right for you, and i dont think it is. you dont sound like you have ADHD or ADD, and that what it is used for. if you want to go out on the streets and buy amps, be my guest, it really isnt any different then abusing an amphetamine script.
 
It sounds like you have major obstacles to overcome.
Focus on those, before introducing more addictive substances to the mix.
 
didnt read about the promethazine at night, im not lecturing im simply trying to get a perspective.

you ask me for my opinion, and then when i give it, you disre, gard any input i try to give??? dont use the sick card please, because it doesnt really seem like you are doing anything to get better. you are not a wounded gazelle in the plains of south africa, you are a human. you can fight, you need to fight.

i didnt comment on anything about your other meds dude, not even about the opiates and benzos. the only thing i said is that you cant expect to feel awake when you take that much promethazine "during the day"


i hate when my mother tells me im on too many meds, like how does she know? she doesnt, so i cant say how much is too much for you.

you asked if adderall is right for you, and i dont think it is. you dont sound like you have ADHD or ADD, and that what it is used for. if you want to go out on the streets and buy amps, be my guest, it really isnt any different then abusing an amphetamine script.

The Prometh number I gave was a max when I abusing it to potentiate my Oxy before I stabilized a bit and stopped getting fucked up 24/7. The last couple weeks I've pulled myself together a little before timgs got way out of hand and started taking more reasonable doses of my pills;enough to just fell good, pain free, depression and anxiety free, and happy, but not to gte high or be nodding or incoherant.
I now on average take 1 25mg pill through the day in the morning, one in the afternoon and two before bed. Sometimes I'll take one in the evening, too. If I really can't sleep even after a Xanax and 20mg "roxy"codone, I'll end up taking 1 or 2 more prometh. I do often feel a little dehydrated and worn out for a few hours the next morning
if I'd taken more then like 100-150mg the day before.

I don't have ADHD but I have chronic fatigue and Have been diagnosed with "mild non-cataleptic narcolepsy" which stimulants are often prescribed for.
I mean I wanna experiment with them, but not be taking them every day.

Is everyone agreed on adderall being the safest/least druggy?
 
didnt read about the promethazine at night, im not lecturing im simply trying to get a perspective.

you ask me for my opinion, and then when i give it, you disre, gard any input i try to give??? dont use the sick card please, because it doesnt really seem like you are doing anything to get better. you are not a wounded gazelle in the plains of south africa, you are a human. you can fight, you need to fight.

i didnt comment on anything about your other meds dude, not even about the opiates and benzos. the only thing i said is that you cant expect to feel awake when you take that much promethazine "during the day"


i hate when my mother tells me im on too many meds, like how does she know? she doesnt, so i cant say how much is too much for you.

you asked if adderall is right for you, and i dont think it is. you dont sound like you have ADHD or ADD, and that what it is used for. if you want to go out on the streets and buy amps, be my guest, it really isnt any different then abusing an amphetamine script.

Both of my severe chronic pain diseases are incurable. They just keep getting more painful until you're on insane amounts of opiates and end up have lot operations to remove/replace certain joints and maybe my pancreas. I fight the pancreatitis by flowing a strict diet (I'm underweight, not fat, it just means I can't eat certain foods), plus taking dozens of vitamin, mineral and more subjects including enzymes every time I east so my body can digest food.
And I have to do a lot of yoga-type exercises, a lot of which can be very painful in order to keep my joints "lose" an to try to slow down the joint-deterioration as much as possible.
So you've got me very wrong if you think I just got diagnosed, thought "oh, well, that's it" an sat on me arse poppin' pills.

I just think the odd upper/adderall would give me what it takes to have to enjoy to go out and have a little fun once in a while.
 
I went to the doctor complaining of chronic fatigue in college and was given Modafinil. It prevented me from sleeping during the day but did nothing to reduce my fatigue, which was almost worse than oversleeping. It's a strange feeling that's not really comparable to amphetamines or other true stimulants. I'm sure it's better for you in the long run than an amphetamine though, especially if you're prone to abusing things.

Never tried Adderall but hope to get a scrip one day. Tired of fucking with these RC stims.
 
Modifinil didn't help me stay awake much. I was prescribed this a few years back and I could literally take and fall asleep on it. I didn't know that they would interfere with my oxycodone at the time and I figured it was tolerance. Thanks for that info lacster. I don't have any experience with other prescription stimulants. Maybe since your GP is already aware of your issue with keeping awake, he can prescribe something.
 
Get off the antis, then you won't be so sleepy. Everything on your drug list makes you sleepy no wonder you're looking for stimulants.

But modafinil sucks dicks, I could fall right back asleep on it. I just wrote up on 2FMA which is a good wakefulness promoter. Tons of stuff works too, why not just go to the corner store and buy coffee?

Adderall you can't get in the UK. Get off promethazine, switch to atarax that will combat anxiety too as well as not being drowsy.
 
Get off the antis, then you won't be so sleepy. Everything on your drug list makes you sleepy no wonder you're looking for stimulants.

But modafinil sucks dicks, I could fall right back asleep on it. I just wrote up on 2FMA which is a good wakefulness promoter. Tons of stuff works too, why not just go to the corner store and buy coffee?

Adderall you can't get in the UK. Get off promethazine, switch to atarax that will combat anxiety too as well as not being drowsy.

I'm not looking for a legit prescription lol (not sourcing here!).
 
You might consider getting off the methadone, xanex, and promethazine, rather than adding a phet to your daily drug repertoire :) Those particular drugs are extremely sedating, so coming off or switching to less sedating meds is probably your best bet.

I wonder if your doctor thinks your are abusing your oxy? It's rather odd to get switched from OCs to methadone, tbh. Your doctor sure as hell wouldn't be prescribing you methadone if he knew you were still taking alprazolam, as that is a particularly notorious and risky drug combination, responsible for many, many deaths.
 
Hi Oxy8_8:)

I browse these forums regularly, and can't help but notice that you seem to be on a mission to take every drug known to humankind. I know your background from your other posts, so i understand how it all started.

I'm a poly-drug abuser myself for my own reasons and I generally don't bother to question people's actions, but I feel like this is a special case...

I have never seen a single poster ask about so many drugs and claim to be on so many things at once, all the while seeking to get on more.

Sorry if it seems judgmental. I guess it is in a way. However, I think you're piling substance upon substance and they never seem to be enough.

Where are you going with all this?
 
Your condition is likely causing your fatigue. If you are still in pain, that is also very fatiguing. Promethazine again, very sedating. Could you go without that med? It's too bad that opies don't help your anxiety; they can cause mood swings in some people. Adderall tends to put me in a bad mood- too much peripheral stimulation. Dexamphetamine works well, 5 mg 3x per day. It is HIGHLY abusable, but no too morish if you keep the dose low. I don't know if your mood problems are the result of your condition, or that it is not being treated enough, or it is a side effect from all the meds. In my case, once the physical issue was adequately treated, the mood and anxiety problems receded. Read a book called The Opiate Cure. Untreated pain can cause anxiety problems. I hope this helps.
 
If you're looking for legitimate alertness and relief from fatigue I, against the other advice, WOULD recommend Nuvigil(armodafilin).. It lasts all day, isn't too taxing on your body, and acts as a nootropic to protect against the cognitive problems caused by alprazolam etc. I'd recommend one a day and split that until you're used to it. It can be quite powerful. Just my 2cents. It's not hard to get Rx'ed, as it's barely controlled or thought of as a drug of abuse. I don't recommend amphetamine in your case, as it could exacerbate your CNS as it could act as a "speedball" of sorts and cause excessive CNS depressant because of ill-timed dosages of your other meds. But.. Think very hard about adding another medicine to your long list. Though I think if you were to add a stimulant, this is probably your best bet. Or even piracetam.
 
I tried modafinil, I think its quite an amazing pill. Although I went extreme beyond the dosage threshold, it has been known to cause life threatening rashes on skin. It does its job very well. A study has shown that the pill causes similar areas in the brain to light up compared to amphetamines.
For me, even though at that time, i was on antis, it kept me awake for a really long time, side effects basically will be the fatigue from being awake, sinus pain and others.
Although it highly potentiates anxiety, blood pressure and at the time of release from the body, it adds a certain smell to the urine and makes me highly irritable to everything, elevates anger due to high irritability.
 
Get off benzos.

I'm a regular modafinil user, and can say it is great. I've tried it with benzos, and benzos take away a lot of the positive effects. Benzos just generally make you a retard. :p

In fact, there is a lot of ongoing research into inverse benzo agonists as cognitive enhancers ("smart drugs")

Modafinil is an awesome study drug, and will keep you awake and fully functional better than d-amphetamine as far as side effects go. I prefer 600mg doses to really get going, and you'll feel very alert without tweeking like all hell. =D

Adrafinil (the pro-drug) is also an alternative if you can't get a script, or a script for enough. It should run you about $1.40 a gram in bulk and is unscheduled most places. Takes about an hour until it is metabolized to modafinil.
 
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