JohnBoy2000
Bluelighter
- Joined
- May 11, 2016
- Messages
- 2,596
First off, my doc is a real old dude that will be retired shortly.
He's had an absolute myriad of health conditions himself, so basically, he's going on whatever he learned in college about 40 years ago, and does absolutely nothing in the way of staying updated with modern medicine and publications.
He had, as he told me, three or four patients to whom he prescribed bupropion previously.
I don't know if it was the generic version or brand, but in any case, they reported back to him with side effects of insomnia and supposedly, extreme nightmares.
He discontinued prescribing it from there forth.
Now - I've gone through several first line treatments, serotonergics, anti-psychotic adjuncts, and given bupropions activity on a different set of receptors entirely, it's something I'd be relatively keen on trying.
It's marketed in my country as Zyban, the smoking cessation agent.
I know there has been dispute between the efficacy of the brand Zyban versus generics - which is, from what I can see, amply supported by a plethora of anecdotal evidence, so maybe that was in part the cause of the mixed feedback my doc received regarding his scripting of this med.
But anyways - my job now, to convince him that this could potentially be a very effective medicine, despite one or two falters in prescribing it thus far.
I need to support that with written information that goes beyond a few copy and pasted anecdotal reports.
That being said, after much googling, I failed to happen across much in the way of substantive clinical trial reports delineating the efficacy of said drug on a widespread basis.
You guys seemed to, in the past, have been much more adept at retrieving this type of information; maybe there's a knack to internet researching that I just haven't got the hang of yet.
In any case - quite a long winded way of saying - can anyone link me to officially concluded and drawn up reports or articles that could assist me in swaying the opinion of my out of date GP, into scripting this a-typical drug??
PS - as an afterthought that maybe you guys can help me on; it's known to suppress appetite also.
That being said, a mood elevation would incite a return in appetite (which is currently very poor) - so perhaps this would balance out?
Makes sense from a lay mans application of general logic, but does it translate that way in the world of pharmacological reality?
He's had an absolute myriad of health conditions himself, so basically, he's going on whatever he learned in college about 40 years ago, and does absolutely nothing in the way of staying updated with modern medicine and publications.
He had, as he told me, three or four patients to whom he prescribed bupropion previously.
I don't know if it was the generic version or brand, but in any case, they reported back to him with side effects of insomnia and supposedly, extreme nightmares.
He discontinued prescribing it from there forth.
Now - I've gone through several first line treatments, serotonergics, anti-psychotic adjuncts, and given bupropions activity on a different set of receptors entirely, it's something I'd be relatively keen on trying.
It's marketed in my country as Zyban, the smoking cessation agent.
I know there has been dispute between the efficacy of the brand Zyban versus generics - which is, from what I can see, amply supported by a plethora of anecdotal evidence, so maybe that was in part the cause of the mixed feedback my doc received regarding his scripting of this med.
But anyways - my job now, to convince him that this could potentially be a very effective medicine, despite one or two falters in prescribing it thus far.
I need to support that with written information that goes beyond a few copy and pasted anecdotal reports.
That being said, after much googling, I failed to happen across much in the way of substantive clinical trial reports delineating the efficacy of said drug on a widespread basis.
You guys seemed to, in the past, have been much more adept at retrieving this type of information; maybe there's a knack to internet researching that I just haven't got the hang of yet.
In any case - quite a long winded way of saying - can anyone link me to officially concluded and drawn up reports or articles that could assist me in swaying the opinion of my out of date GP, into scripting this a-typical drug??
PS - as an afterthought that maybe you guys can help me on; it's known to suppress appetite also.
That being said, a mood elevation would incite a return in appetite (which is currently very poor) - so perhaps this would balance out?
Makes sense from a lay mans application of general logic, but does it translate that way in the world of pharmacological reality?