I think it's a undisputed fact tramadol has had some very postie effect at low to moderate doses on depression increasin motivation due to it SNRI action perhaps in combo with its weak opiod affinity....although as a seasoned tramadol user I would say too much trammy negate any kind of opiod high and starts to push the over stimulation buttons....unpleasant for those sensitive to stims.
Benzos can counter this just as ritalin can increase it.....tramadol just seems to follow whatever high u r choosing.....upper or downer.
However my question- from my poor memory the snri qualities of tramadol are closest to venlafaxine .....Also with my old anti-d of choice mirtazapine a NASSA or TECA higher doses give a completely different effect than lower.....as most doctors don't seem to fathom as they are used to saying "okay proactive 20 mg is not effective, let's bump u to 40-60-8mg etc. Mirtazapine is stimulating at doses and sedating/simple carbon cravine at lower.
Anyhow I am meandering as usual......so my question. To use tramadol as a anti d self prescribed with what I believe can be a 12hr+ Half-life then dosing say in 2/3 x 50mg HCL everyday would give stable levels.
As some of know to chase a opiod high a 20 min re dose works well although with my tolerance I would do that alongside a benzo and/or a CWE.
But.....For anti-d purpose I'd assume consistent blood plasma Leveld and no recreation extra dosing would given a even SNRI type effect?
Thoughts?
Cheers
Benzos can counter this just as ritalin can increase it.....tramadol just seems to follow whatever high u r choosing.....upper or downer.
However my question- from my poor memory the snri qualities of tramadol are closest to venlafaxine .....Also with my old anti-d of choice mirtazapine a NASSA or TECA higher doses give a completely different effect than lower.....as most doctors don't seem to fathom as they are used to saying "okay proactive 20 mg is not effective, let's bump u to 40-60-8mg etc. Mirtazapine is stimulating at doses and sedating/simple carbon cravine at lower.
Anyhow I am meandering as usual......so my question. To use tramadol as a anti d self prescribed with what I believe can be a 12hr+ Half-life then dosing say in 2/3 x 50mg HCL everyday would give stable levels.
As some of know to chase a opiod high a 20 min re dose works well although with my tolerance I would do that alongside a benzo and/or a CWE.
But.....For anti-d purpose I'd assume consistent blood plasma Leveld and no recreation extra dosing would given a even SNRI type effect?
Thoughts?
Cheers
