Amphetamines and liver work

[fakeplastictrees4]

Hey all, just to clarify this is not a post regarding how to pass a blood test because I am not getting drug tested.
I have to do monthly blood tests because of a medication that I'm on at the moment and it just occurred to me that my next results may be skewed because of my use of amphetamines. I have a prescription for Ritalin and I have been taking Vyvanse as well since about Mid february with a few breaks here and there. I haven't ingested any Vyvanse/ritalin for 5 days up until today. (50mg of vyvanse at 9 in the morning)

So anyways I am being tested tomorrow morning for: Creatinine (CRE), Gamma Glutamyl Transferase(YGT), alanine aminotransferase (ALT), Haptoglobin (Hp), LDL, HDL, Sodium (Na), Triglycerides (TRG), CHO, SK and SPG

Do amphetamines influence any of these tests? I only have one month left but I'd still like to know.
I am pretty sure they affect the thyroid....
I'll ask the nurse that is drawing my blood tomorrow anyways but I'd still like to get some other input and scientific info...I tried to look all of this up but my medical knowledge is quite limited...
thanks : )

 

[eukaryote]

Alright, I'll bite. I just flipped though my copy of the Merck Manual, as well as my notes from back when I was still in school, and I see no mention of amphetamine affecting any clinically used liver function tests. I've also never seen it affect any liver function tests, including the ones you mention, in any of my patients, and all things being equal, there is no reason why it should. Of course, it could affect many of them if you are a hardcore tweaker who does not eat right and who is bleeding body mass off as a result, creatinine and triglycerides would be affected, as would Na if you are improperly hydrated or not taking in adequate sodium. I doubt this is the case as hyponatermia is a medical emergency.

tl;dr it is very unlikely that reasonable use of amphetamine will affect any of the test. Amphetamine is a substrate of several of the P450 oxidase enzymes, but they are special tests and mainly of interest to drug studies.

edit: Let me put a caveat that I cut people open and stitch them back together; as such I am not a hematologist or a pathologist and I am speaking mainly from theory here, so don't nail me to the cross if I overlooked something.

 

[effie]

^ Agreed, I can't think of any way amphetamine could affect those bloods bar malnutrition or potentially rhabdomyolysis (breakdown of muscle tissue, explanation for OP not you eukaryote!) but that would be in an acute toxicity case not moderate Vyvanse use. You should be all good, fpt, as far as I can tell.