Long post warning:
I have reviewed this thread fully and attempted to understand as much as possible as a "layman". I have attempted to research the below answers but the technical data is very difficult to interpret in a useful way without the required skills.
Can I confirm the accuracy of some conclusions? Any wording that i think may be perceived incorrectly, be inaccurate or i feel my not describe what i mean to satisfactory level will be in "". Dont go to any effort but if you know offhand...
1. Amphetamine Psychosis is in fact caused by physical "trauma", deficiencies and other easily explained physical conditions that would be considered unhealthy (for example hypoglycemia(hyper?)), and not the intended effect of the drug proceeding to a level where the experience is negatively perceived.
If so how does this explain experiences of similar psychosis presenting immediately through extreme doses as the first administration. Unless the physical conditions/requirements are created instantly by this, but it is my understanding that it will take some time to "deplete" the body to the point needed to cause psychosis.
2. Does the above conclusion also explain the perceived decreased mental faculties, paranoia, strange thoughts etc that can still be perceived as false, controlled etc. Basically the blatantly obvious negative mental states of mind that directly conflict with the expected effects of the drug. Can these be interpreted as an indication of the "beginnings" of an unhealthy physical state that would eventually progress to psychosis, or is this still subjective perception of your experience. Is there a perceived cut over point between subjective experienced based perceptions and mental states directly linked physical "trauma"? I have tried to repeat and reframe this to get my understanding across. Basically is there a functional way to interpret physical concerns during the experience.
3. Lastly where does the commonly accepted impact of sleep deprivation come into this? I understand it is a big part of the risk of psychosis. Does the sleep deprivation contribute to psychosis through exacerbating the physical "trauma" explanations for psychosis or does it impact in some other way. This was absent from this thread as far as i remember.
4. And at the risk of perhaps delving into the realm of pure theory: Any thoughts as to why the symptoms of psychosis in this regard, a seemingly chaotic unbalanced physical state of "unhealth" seem to present as rather surprisingly specific and consistent experiences which seem to follow some logical path. It would would seem the symptoms should present as they would with other forms of brain distress like random confusion, reduced mental function, memory loss, unconsciousness etc. Instead we see the same theme consistently.
After reading many experiences of amp induced psychosis it seems to almost always present as a feeling of absolute certainty of impending danger from others or the environment which is perceived as being watched, followed etc. This feels like a hardwired specific instinctual response to a certain issue, but it doesn't seem to correlate to the root cause being physical distress.
My conclusions in an attempt to make sense of this:
1. The physical distress causes an appropriate mental sense of overall danger without a clear source, which we then imprint on our environment in a conscious effort to make sense of and identify the source of danger.
2. What is most likely more accurate is that the fight or flight response is at work here in extremes, which is what i always reasoned, but now i question this due to my new understanding of psychosis being caused by physical distress and not the SNS.
3. Lastly is it simply a result of the combination of physical distress and increased SNS activity logically resulting in the symptoms.
I am going to take this opportunity to risk the below questions which are more irrelevant and experience based, which I find interesting anyway. Feel free to ignore.
5. Can the perceived enhancement of certain mental tools during the experience be confirmed as accurate and explained technically/medically or would it be technically accurate to write off any perceived enhancement to a subjective perception of the experience? (EG. Enhanced creative writing abilities are simply due to enhanced confidence and not a physical effect for example improved access to the creative centers of the brain). This question is very broad and does not need answering directly. Let this rather be a clarification of context for the next more specific question.
5. I would like to know if the perceived enhanced senses (specifically smell and audio) during the experience can be technically explained, confirmed as accurate or reasonably concluded, even if just in theory using scientifically backed assumptions/methods, as in fact an enhancement of the senses for all intents and purposes. Or must we conclude this perception is always a purely subjective experience that is equivalent to a hallucinatory response, when considering this from a technical or scientific point of view.
To reframe: If i where to ask a medical/scientific professional with all the required knowledge whether I can logically accept, trust or assume that my senses are in fact enhanced and could therefore be theoretically useful on some way, what would they say?
The sense enhancements are really the only perceived enhancement that i think
might have some basis in fact but really i have no idea.
I hope none of the above makes no sense or is plain stupid but feel free to let me know if it is.
Lastly a random thought. I think it would be really awesome and interesting for somebody with all the knowledge and experience to take all the info in this thread and all relevant and confirmed as accurate data and do a write up or paper of some sort that explains the perfect process, requirements, actions etc for the use of amphetamines recreationally and functionally based on theoretical, technical and scientific conclusions etc.
To clarify this would look like a detailed and step by step owners manual explaining exactly how to use amphetamines including everything that should be considered, physical defense strategies, supplementation, detailed dosage guides etc. A functional usable guide for anybody to understand.
I'm not asking or expect anybody to do this, simply thought that the whole concept of a functional summary of everything we know to date would be a worthy project and i dont think a well packaged and presented version of this idea exists anywhere, or does it?
Hell if i had the skills to do this responsibly, i would really enjoy this project i think. Also would be an awesome HR sticky for Other Drugs im sure. Anyways, just a random idea.
Love ADD and thanks to all the contributors, I could spam questions here all day, but I shall resist

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