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  • BDD Moderators: Keif’ Richards | negrogesic

Amphetamine induced psychosis

chrisincville

Bluelighter
Joined
May 13, 2015
Messages
316
I'm wondering if a person that has experienced a state of psychosis induced by amphetamines is more susceptible to it with continued use of said drug (non regular use).

In other words, if you experience psychosis once, are you more vulnerable to entering it the next time you use the drug than if you never experienced it? I think I read somewhere that you are.
 
Yes definitely. Once i hit 48 hours of being awake now it starts. And only gets worse the longer I stay up.
 
Mine has generally been not a result of time awake, but moreso sped up by burning up calories with little to no nutritional intake. I didn't realize it at the time of course.
 
The psychosis on crystal meth is one of the more enjoyable parts i always felt.

Nothing like being up for three days and taking a shower and listening to Baker Street play through the nonexistent speaker system in your bathroom.
 
Isnt psychosis part of it? Like Derailed, I used to go with it...and LOL the non-existent speaker!! They seemed to be wherever I went.
 
chrisincville, you should either learn to enjoy it or avoid the drugs that cause it, if it makes you uncomfortable. Frankly, I've had some pretty interesting conversations with myself during those time periods, and when I'm sober it is slightly upsetting that nothing talks back when I try to talk to myself.

It happens to plenty of people, for one reason or another, and it mimics schizophrenia by the medical standard. If you got it once, it will happen again, you can be almost sure of that. Whether its sleep deprivation, the drugs, or a combination of the two, it always goes away.

Unless you have schizophrenia for real, and it has been undiagnosed as an underlying condition. Meth and Amphetamines can trigger previously undiagnosed schizophrenia if an individual is prone to it (check family history, usually the best way for doctors to anticipate that). Hell, in lab experiments they actually dose rats with Methamphetamine to mimic schizophrenia, so they can study the behavior of schizophrenics. Since they can't just infect someone with a mental disease, I guess that is the next best thing.
 
Has anyone had a drug induced psychosis from cocaine and weed? Friend of mine has been on olanzapine teva for 2 weeks now and still feels detached from his friends and doesn't want to speak to us, also still thinks people hate him for things he has done, and makes up things in his head which he believes are true. Wondering if anyone knows how long it will take for him to go back to normal? He's been taking drugs on and off for 5 years. Took MDMA every weekend for 4 months and then 4/5 weeks back, did cocaine 4 days in a row one week, then 3 days in a row the next week before showing strong signs of schizophrenia. Also he smoked weed nearly everyday for the past 2 years. Just wondered what the average time for him to start getting back to normal would be? Just worry everyday
 
The science has yet to catch up about the mechanisms behind, but there are some truly amazing findings from the last years. It's maybe much more about an immune response because of over excitation of the neurons, excessive oxidative stress etc. than a purely mental thing as many thought and think ... :)

Look at scholar.google.com or PubMed for things like psychosis immune response, schizophrenia & interleukin-6, NADPH oxidase, glutamate etc... I hope we'll have much better treatments available in some years.. :)

Until then, well.. it's disputed but I'm really against neuroleptics (dopamine antagonists), in my eyes this was the wrong way to go at least for a good part of the people.. they are just causing serious and possibly semi-permanent adverse effects from time to time.. it's not the dopamine that is causing the psychosis.

What helps is more about the general sedation, anti-histaminergic, anti-adrenergic, maybe GABAergic and very probably 5-HT2A antagonistic/inverse agonistic effects (mirtazapine, trazodone are readily available for example). Even some anticonvulsants like pregabalin or gabapentin might be better choices for drug induced psychosis than those nasty toxic neuroleptics!

Blocking dopamine will possibly contribute to these negative symptoms like paranoia, anxiety, feeling detached etc. and certainly hinder the recovery in my eyes.

(Edit: As a side note, ever noticed how many people in psychiatry are chain smoking? That's -part of- because they try to alleviate the dopamine blocking shit.)
 
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I've had a few nasty experience with amphetimine psychosis but those were very isolated incidents most like caused by malnutrition and extreme lack of sleep. Most I get now are auditory and I just try to ignor them. But yeah if you use meth fairly often you can pretty much count on it happening.
 
Lack of sleep is may cause of psychosis in drug users. Your brain needs rest but not just rest it actually needs to go through sleep cycle each night if you do not go through the cycle your brain will just keep banking it up until you hit a wall
 
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