CluckinChuckin
Greenlighter
- Joined
- Aug 29, 2014
- Messages
- 10
I've got a question I'm curious about, some of what I say next is more than likely total garbage and holds no scientific basis or reality. However its the way I kind of think things work so no doubt someones going to shoot me down for inaccurate information and thinking but that's why I'm asking I as can't get my head around it, so here goes.
I have been trying to kick Heroin recently, well actually about 10 years but I've been putting some serious effort into it lately, manage to get clean but it only last a week or two at most. in the past I always just went cold turkey, smoked my last bag and the waited it out, a week of Sweats, Shits, Shivers, Shakes, Sick, but no sleep then a week of feeling better but not great, finally being able to eat, a few hours sleep bit more energy less pain, hey you know the score. Then I discovered Buprenorphine OH! MY! GOD! this stuff is AMAZING!! truly, my new method of detox is smoke my last bag around 5pm sleep at around 10/11 ish and then when I wake the next day its usually 15 or so hours since my last use and I'm suffering withdrawal symptoms so I take a load of Buprenorphine, I've found 16mgs spread over 4 hours works great, totally feel the benefit, I still get a few bad symptoms, that shiver that runs through you, a few aches and pains but so much better than cold turkey, then after that I gradually get better and better over the next week week without the need to re-dose, a week later I'm back at work and I feel fine, so good in fact I decide its time to celebrate by getting some gear lol.
Here's what I don't get as I said previously this is just my thinking not scientifically factual. When a non opiate tolerant individual takes opiates for example Heroin they feel the effects, enjoy it, take more, continue to take it every day for say 12 months, their opiate receptors become enlarged to compensate, they need more and more to feel the effect.
Then they stop the body and enlarged opiate receptors are craving more opiates so they take some, the cravings die away, until next time. The vicious cycle has begun.
But lets say the next time they they begin to get withdrawal symptoms they take Buprenorphine, this fills the opiate receptors and satisfies the craving, the individual is still in Heroin withdrawal but the Buprenorphine is masking it, given its long half life it continues to act for the next few days allowing the heroin to leave the body, by the time it wears of the individual is past the worst of heroin withdrawals.
But why aren't they addicted to Buprenorphine I know its not the same opiate they were addicted to before but it dose the same job, it attaches to the enlarged opiate receptors in place of the Heroin so why when it wears off is the body not craving more?
I just find it strange how you can use a single large does of Buprenorphine when heroin withdrawal starts and it mask the negative effects of detox long enough to make it bearable and virtually painless, I assumed there would be some cross tolerance issues, swapping one drug for another but this doesn't appear to be the case, wonder if anyone could shed some light on it for me? thanks.
I have been trying to kick Heroin recently, well actually about 10 years but I've been putting some serious effort into it lately, manage to get clean but it only last a week or two at most. in the past I always just went cold turkey, smoked my last bag and the waited it out, a week of Sweats, Shits, Shivers, Shakes, Sick, but no sleep then a week of feeling better but not great, finally being able to eat, a few hours sleep bit more energy less pain, hey you know the score. Then I discovered Buprenorphine OH! MY! GOD! this stuff is AMAZING!! truly, my new method of detox is smoke my last bag around 5pm sleep at around 10/11 ish and then when I wake the next day its usually 15 or so hours since my last use and I'm suffering withdrawal symptoms so I take a load of Buprenorphine, I've found 16mgs spread over 4 hours works great, totally feel the benefit, I still get a few bad symptoms, that shiver that runs through you, a few aches and pains but so much better than cold turkey, then after that I gradually get better and better over the next week week without the need to re-dose, a week later I'm back at work and I feel fine, so good in fact I decide its time to celebrate by getting some gear lol.
Here's what I don't get as I said previously this is just my thinking not scientifically factual. When a non opiate tolerant individual takes opiates for example Heroin they feel the effects, enjoy it, take more, continue to take it every day for say 12 months, their opiate receptors become enlarged to compensate, they need more and more to feel the effect.
Then they stop the body and enlarged opiate receptors are craving more opiates so they take some, the cravings die away, until next time. The vicious cycle has begun.
But lets say the next time they they begin to get withdrawal symptoms they take Buprenorphine, this fills the opiate receptors and satisfies the craving, the individual is still in Heroin withdrawal but the Buprenorphine is masking it, given its long half life it continues to act for the next few days allowing the heroin to leave the body, by the time it wears of the individual is past the worst of heroin withdrawals.
But why aren't they addicted to Buprenorphine I know its not the same opiate they were addicted to before but it dose the same job, it attaches to the enlarged opiate receptors in place of the Heroin so why when it wears off is the body not craving more?
I just find it strange how you can use a single large does of Buprenorphine when heroin withdrawal starts and it mask the negative effects of detox long enough to make it bearable and virtually painless, I assumed there would be some cross tolerance issues, swapping one drug for another but this doesn't appear to be the case, wonder if anyone could shed some light on it for me? thanks.
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