Alcohol Derivatives of Carbamates

[Hammilton]

I'm wondering if anyone here is aware of any research on the CNS depressant effects of alcohols more complicated than propanol and pentanol.

I have the opportunity to get a huge amount of 1-ethynylcyclohexanol and/or 1-propynyl, which appear to be good depressants, but there's little research.

I'm wondering how many other alcohol derivatives of carbamates are worth exploring. Emylcamate might be a good one, but I probably wouldn't bother with meprobamate and carisoprodol. I wonder how they'd be with one of the carbamate groups removed.

Anyway, there are literally hundreds of potential GABAergic depressants derived structurally from ethanol, from simple stuff 2-methyl propanol or 2-chloromethyl propanol to more complicated stuff, like 1-ethynylcyclohexanol, and everything in between.

But what's actually known about them?

Unfortunately to synth them all- or even a decent portion- it'd get really costly.

 

[eurolite]

Be careful.

Be careful. I don't know too much about alcohol derivatives other than the fact some are VERY toxic some even corrosive. A place I used to work used an alcohol derivative for cleaning ink off a special jet and the shit would even slowly melt through HDPE plastics... Hell even ethanol is toxic as hell not a category of drugs I would mess with.


- If you want that style of CNS depressant I recommend GBL it is space booze they should replace the ethanol in our drinks with low doses of GBL... GBL is a little harsher on you than GHB but still not nearly as bad as ethanol and provides a much more pleasurable high.

GBL is cheap to obtain and without going into much detail because of the rules here it is very very simple to do a GBL -> GHB synthesis.

 

[onmyway]

good god man, what do you know about the metabolites of these alcohols? i'm thinking that a lot of these could cause some kind of acidosis like propanol does.
i wonder if anyone even knows how these are metabolized?

 

[fastandbulbous]

You don't need the carbamates as the alcohols on their own are active (but usually have a hideous after taste)