That's interesting as I wouldn't consider 6mg of subs per day (total) to be that much of a script, and neither would my pain doc (don't worry - he's got a waiting list of people who want his services, so he's not going to BS me to keep me on subs). I get zero mood benefit from taking them. They just dull my chronic pain. I was on 12mg per day when I transitioned from percs to subs, cut it to 6mg, and haven't had a need to increase. That's why it's hard for me to get off of them. Whereas with the percs and oxycontin I kept having to take more and more. That being said, I agree with you that they are contributing to my lethargy. If the subs are causing the edema in my legs, that is definitely causing lethargy because that's water weight. It's harder to move around. The problem I have with the subs is that they are BY FAR the best pain med when it comes to controlling my chronic pain, which is pretty intense. In fact, my personal experience with subs has convinced me that chronic pain patients should actually be given subs and should never be given any of the usual opiates if they are going to use meds. Percs are okay if you just got out of surgery and need help for a few days. Other than that, they suck for chronic pain. They just stop working after awhile. My pain doc and I have discussed the possibility of doing a very slow taper to see if the edema goes down and if I feel better. But it's a damn if you do, damn if you don't situation with me. I have been thru 3 rounds of physical therapy, 2 rounds of acupuncture, 6 months of soft tissue therapy, pain injections, compound pain creams, and far too many visits to the chiropractor. With the subs, I only have to pay the chiropractor $25 every three weeks. Without them....God knows how many times I would be going in to see him. The whole situation sucks. But the booze has to go first because it's not helping ANYTHING. I am very aware of the dangers of subs though.....the longer and longer you take them, the harder and harder it is to get rid of them....even with a good taper. I gosh damn hate it. My whole family is screwed. My sister just had to go on disability for the rest of her life at 39 due to chronic pain and mental health problems. My mom had severe neuropathy, arthritis and carpel tunnel syndrome. Got her hips and knees replaced. Fortunately she died peacefully, although she died the death of a cigarette smoker.