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  • Trip Reports Moderator: Xorkoth

A DXM 2 week long life changing experience?

SwampFox56 said:
Dextromethorphan - being that it downregulates Glutaminergic activity would decrease that excitation.
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DXM only inhibits glutaminergic activity during its acute effects. dissociatives cause rebound excitotoxicity (excessive upregulation)
 
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