Kratom 7-Oh/Pseudo ??

[KorruptedOne]

Hey everyone! Let me just make this short and simple.

Male: 33 158lbs 6ft

Dosage: 50-250mg per 4/6 hours. Varies ( Still playing with dosage )

Just recently within the past year I’ve been diagnosed with lumbar root disorder. I’ve been going through 24/7 pain on my left side as my L4/L5 nerves are being pressed on. So my point being Hydros and Oxy do not really help. I’ve been using this new 7-oh MIT and 7-oh Pseudo. Unfortunately my intake is up to 300mg when I wake up in the morning in full blown pain. Can’t even walk until it kicks in. Now I normally have to take 120mg of hydros to get out of pain or least 80mg of oxy. Since I’m new to this what’s the best dosage to take for 7-oh mit and also for 7-oh pseudo? Remind you I’m not looking to get high. I just want to be able to enjoy everyday activities…. So any advice would be greatly appreciated or even helpful stories related to 7-mit or 7-Pseudo.

If you have any questions for me to help me find my best dosage please ask away!

 

[abefourth]

I'm sorry you're going through this. I have peripheral neuropathy and take medication that only works on and off. Since your post I've been thinking about it and wanting to try 7-oh mit. Maybe it would help with my pain.
I'm sorry this isn't more helpful but I'm looking into 7-oh MIT and will see if I can figure out if anything works. Maybe someone can help you before then.
Don't give up.

 

[ak2013]

I’m in a similar position - severe peripheral neuropathy due to genetic disease and use Kratom/7OH to ease the pain. The best advice I can give is to start low and stay as low as possible while killing the pain. I’d recommend starting around 10mg of 7OH and go up from there until you hit the sweet spot. I noticed that Kratom tolerance doesn’t necessarily translate to 7OH tolerance when you start, since most leaf Kratom and even extracts now are very low in 7OH. My sweet spot ended up being about 40-50mg taken a few times a day. I will say, it’s a bitch and a half to quit, especially if you have severe body pain. I’m currently planning to start tapering/quitting as 7OH will likely get banned at some point in the US. The whole Kratom/7OH ban fad has started back up in the US

 

[KorruptedOne]

I’m in a similar position - severe peripheral neuropathy due to genetic disease and use Kratom/7OH to ease the pain. The best advice I can give is to start low and stay as low as possible while killing the pain. I’d recommend starting around 10mg of 7OH and go up from there until you hit the sweet spot. I noticed that Kratom tolerance doesn’t necessarily translate to 7OH tolerance when you start, since most leaf Kratom and even extracts now are very low in 7OH. My sweet spot ended up being about 40-50mg taken a few times a day. I will say, it’s a bitch and a half to quit, especially if you have severe body pain. I’m currently planning to start tapering/quitting as 7OH will likely get banned at some point in the US. The whole Kratom/7OH ban fad has started back up in the US

Hey thanks for the response! Wanted to say as an ex addict of Opiods in general between Oxy and Subox taking 120mg plus a day this Kratom extracts are not as bad for withdrawals. I have yet to have them even when not taking them for days. Now unfortunately I have to take them everyday and I’ve been doing some playing with the dosage and I’ve found that pure 7-ohMIT is a lot weaker than taking just Pseudo or 7-OhMit(Pseudo) combo. So I found that the mix helps a lot more long as it’s more Pseudo than 7-ohMIT. Kama makes a great brand that is 22.5mg 7-ohmit and 2.5 mg Pseudo per 1/4 serving. I also bought the Kama Pseudo by itself and it was 100mg total. So I take 25mg Starting dose of Pseudo tablet then two servings of 7-Ohmit/Pseudo which are 22.5mh 7-ohmit and 2.5mg Pseudo totaling 5mg of Pseudo and 45mg of 7-Ohmit plus the 25mg = 30mg of Pseudo(My: morning dose). Point being if I was to just take the 7-ohmit I would have to take 150mg (doesn’t matter the brand) per dose that only last 30mins to 3 hours. So after doing this for two days I’ve noticed I only have to take a higher dose as calculated above in the mornings and then only taking 5mg Pseudo and 20mg of 7-Ohmit every 6-8 hours up until bed. Onset is about 10-30 mins tops. Last 4-8 hours. Gets rid of 87% of pain if not all of it. Downsides: Minor Headaches, Redness of the face, Hot sweats, Dizziness, nausea. Not all of these symptoms occur at once but if the dosage is off one or two will occur. I also take Zofran for nausea and Excedrin for headaches as I tend to get migraines aside from the kratom extract. So hope that helps anyone! And remember to dose responsibly! Never heard of an OD on kratom but I’m sure it exist. Stay safe everyone!

 

[ak2013]

Hey thanks for the response! Wanted to say as an ex addict of Opiods in general between Oxy and Subox taking 120mg plus a day this Kratom extracts are not as bad for withdrawals. I have yet to have them even when not taking them for days. Now unfortunately I have to take them everyday and I’ve been doing some playing with the dosage and I’ve found that pure 7-ohMIT is a lot weaker than taking just Pseudo or 7-OhMit(Pseudo) combo. So I found that the mix helps a lot more long as it’s more Pseudo than 7-ohMIT. Kama makes a great brand that is 22.5mg 7-ohmit and 2.5 mg Pseudo per 1/4 serving. I also bought the Kama Pseudo by itself and it was 100mg total. So I take 25mg Starting dose of Pseudo tablet then two servings of 7-Ohmit/Pseudo which are 22.5mh 7-ohmit and 2.5mg Pseudo totaling 5mg of Pseudo and 45mg of 7-Ohmit plus the 25mg = 30mg of Pseudo(My: morning dose). Point being if I was to just take the 7-ohmit I would have to take 150mg (doesn’t matter the brand) per dose that only last 30mins to 3 hours. So after doing this for two days I’ve noticed I only have to take a higher dose as calculated above in the mornings and then only taking 5mg Pseudo and 20mg of 7-Ohmit every 6-8 hours up until bed. Onset is about 10-30 mins tops. Last 4-8 hours. Gets rid of 87% of pain if not all of it. Downsides: Minor Headaches, Redness of the face, Hot sweats, Dizziness, nausea. Not all of these symptoms occur at once but if the dosage is off one or two will occur. I also take Zofran for nausea and Excedrin for headaches as I tend to get migraines aside from the kratom extract. So hope that helps anyone! And remember to dose responsibly! Never heard of an OD on kratom but I’m sure it exist. Stay safe everyone!

Unfortunately for me I have severe nerve damage in my legs and my back, so the RLS of Kratom/7OH WDs absolutely wreck me. The other symptoms I can mostly deal with, it’s that RLS and muscle spasms that keep me up for days that really makes it difficult

I do agree with the 7OH alone being a bit “weak” especially for pain reduction, I use a combination of Kratom extract and 7OH to keep the nerve pain at bay. Personally I never enjoyed Pseudo, it was too much of an “upper” to be and gave me this weird electric kind of energy that doesn’t go well with helping sleep. I tried it a couple times but never got fully into it. There’s also MGM-15 on the market now, which I’ve heard is great for pain management but also has the downside that you can OD from it, unlike 7OH which has no OD potential. You might want to give that a shot starting at about 1/4 your current 7OH dose, as I know people have tolerated it pretty well.

As far as the side effects you mention go, I’ve never had any of those issues. I’ve been a consistent Kratom user since 2018 after first trying it in the early 2010s, and a 7OH user since 2024. I get super constipated from zofran so that would be a nightmare for me, but everyone’s variable. You may have a slight allergy to one of the alkaloids. Extracts may do you better

 

[Mycophile]

Is 7-OhPseudo just another newer extract like 7-Oh Mit? Is it weaker or stronger? And just curious, but how does it compare to regular extracts like OPMS black?

I use plain leaf and regular extracts but people have advised against 7-Oh Mit so I've decided to never use it. So seeing as that's too addictive for my tastes, would people agree someone like me who doesn't want an even higher tolerance or any more addictive extracts would also want to avoid 7-Oh Pseudo?

Also, I only just heard about MGM-15 and MGM-16, but are these around the same level of strength as 7-Oh MIT and would someone like me also want to avoid them?

And really, what are the biggest differences between the way these different extracts feel? (7-Oh MIT, 7-Oh Pseudo, MGM-15 and MGM-16)

Do some of these feel like Oxy or Hydro? Cause I do love those, but I also stay away from them. Plain leaf Kratom and regular extracts are enough for me.

 

[ak2013]

MIT, 7-OH, and Pseudo are all separate compounds. MIT (Mitragynine) is the most common alkaloid found in raw Kratom lead. 7-OH (7-hydroxymitragynine) is another compound found in raw Kratom, though in very minuscule amounts. It is more potent than standard MIT. Pseudo (pseudoindoxyl) is a downstream metabolite of 7-OH, and it does not substantially exist in natural Kratom, it is entirely lab made. In the body, when you consume Kratom, your body metabolizes it into 7-OH, which then metabolizes into pseudo. So the further down the chain you get, the “stronger” you get but they are distinctly different compounds. OPMS Black is a “natural” extract of Kratom and contains very low levels of 7-OH and no pseudo.

Basically think of this as a weakest to strongest chart:
Kratom/mitragynine
7-OH
Pseudo

You can think of it kind of like the difference between codeine, hydrocodone, and morphine. They’re entirely different, and different strengths, but all get metabolized into the same compound in the body

 

[cnnka]

Does combining pseudo with 7OH makes the 7OH last longer ? Cause at 2 hours exactly I’m sober and have strong urge to redose.

 

[ak2013]

Does combining pseudo with 7OH makes the 7OH last longer ? Cause at 2 hours exactly I’m sober and have strong urge to redose.

Yes, combining the 2 will make it “last longer” as pseudo has a much higher affinity for the receptors, it’s basically makes them compete for occupancy. It also causes a bit of a bottleneck in metabolism so both stay in your system longer. Pseudo has a typical duration window around 6 hours, while 7Oh is more like 2.5-4. However, stacking the 2 also means tolerance will rise far more rapidly. If you’re looking for all day pain relief, my recommendation would be small doses of 7OH throughout the day, which is what I do

 

[KorruptedOne]

Yes, combining the 2 will make it “last longer” as pseudo has a much higher affinity for the receptors, it’s basically makes them compete for occupancy. It also causes a bit of a bottleneck in metabolism so both stay in your system longer. Pseudo has a typical duration window around 6 hours, while 7Oh is more like 2.5-4. However, stacking the 2 also means tolerance will rise far more rapidly. If you’re looking for all day pain relief, my recommendation would be small doses of 7OH throughout the day, which is what I do

I use to do the combo then I started taking the Pseudo at 15-30mg per dose and redosing every 6-8 hours. Only going into full blown pain once a day and that’s after I’ve been asleep for 2-6 hours. I also don’t take this for the trill! I use for actual chronic pain. So after I stopped the 7-oh and stayed with just Pseudo I’ve seen a huge difference. Also dosing high with pseudo like 40mg+ you will start to nod off.

 

[KorruptedOne]

Yes, combining the 2 will make it “last longer” as pseudo has a much higher affinity for the receptors, it’s basically makes them compete for occupancy. It also causes a bit of a bottleneck in metabolism so both stay in your system longer. Pseudo has a typical duration window around 6 hours, while 7Oh is more like 2.5-4. However, stacking the 2 also means tolerance will rise far more rapidly. If you’re looking for all day pain relief, my recommendation would be small doses of 7OH throughout the day, which is what I do

Hey Ak2013 know anything bout

Oxonol? I’ve seen the Alts for 7-oh and it seems it’s Oxonol and Pseudo.​

 

[Keif' Richards]

I am nervous whenever I hear people with chronic pain issues discussing these high-powered Mitragynine analogs. This is really a very unregulated market. We have had multiple reports of products sold as said extract(s) containing Fentanyl and/or other powerful synthetic Opioids. These extracts are already made to capitalize on the name recognition and relative safety of Kratom. These high-powered extracts are marketed as if they are "natural". These chemicals are indeed found within the plant naturally, though the proportions are so low that it is only commerically viable for these companies to make them fully-synthetically. If they are already doing a complete synthesis to make their product, why would they make a product that costs much more to make when the only real objective is to put a powerful Opioid in the hands of the consumer?

I don't like it because I feel chronic pain patients are being forced into these situations and are made to feel as if there is a solution in these products. In the best of circumstances, it seems that these Mitragynine analogs produce tolerance at a pretty astronomical rate. Every day, I'm reading about people becoming saturated and no longer being able to receive meaningful analgesia. A lot of these people end up with the same pain and in addition, a crippling dependency on these products.

Furthermore, who knows when this stuff is going to be outlawed. It seems like different jurisdicions are banning it on an ongoing basis. I feel like a blanket ban can't be far behind. I didn't want to come here just to monger fear. I really care about all of you guys. Chronic pain is terrible. Opioids can be used to treat chronic pain, but only if it is done with an incredible amount of discipline and only if the dosage is kept to the lowest possible level. Another downside to these products is that patients are left to self-diagnose and titrate. I don't care who you are. If you are struggling with pain and have access to Opioids, it's foolish not to have someone involved who can help you make the best decisions. It's too difficult to make these decisions all on your own.

 

[KorruptedOne]

I am nervous whenever I hear people with chronic pain issues discussing these high-powered Mitragynine analogs. This is really a very unregulated market. We have had multiple reports of products sold as said extract(s) containing Fentanyl and/or other powerful synthetic Opioids. These extracts are already made to capitalize on the name recognition and relative safety of Kratom. These high-powered extracts are marketed as if they are "natural". These chemicals are indeed found within the plant naturally, though the proportions are so low that it is only commerically viable for these companies to make them fully-synthetically. If they are already doing a complete synthesis to make their product, why would they make a product that costs much more to make when the only real objective is to put a powerful Opioid in the hands of the consumer?

I don't like it because I feel chronic pain patients are being forced into these situations and are made to feel as if there is a solution in these products. In the best of circumstances, it seems that these Mitragynine analogs produce tolerance at a pretty astronomical rate. Every day, I'm reading about people becoming saturated and no longer being able to receive meaningful analgesia. A lot of these people end up with the same pain and in addition, a crippling dependency on these products.

Furthermore, who knows when this stuff is going to be outlawed. It seems like different jurisdicions are banning it on an ongoing basis. I feel like a blanket ban can't be far behind. I didn't want to come here just to monger fear. I really care about all of you guys. Chronic pain is terrible. Opioids can be used to treat chronic pain, but only if it is done with an incredible amount of discipline and only if the dosage is kept to the lowest possible level. Another downside to these products is that patients are left to self-diagnose and titrate. I don't care who you are. If you are struggling with pain and have access to Opioids, it's foolish not to have someone involved who can help you make the best decisions. It's too difficult to make these decisions all on your own.

Chronic pain is a capital market problem. Companies and Labs and Doctors all fighting to keep it going to make money. We know the deal when we buy these. Unfortunately some of us can’t afford healthcare and who is going to pay out of pocket? Money is the root to all evil. Get them the products then get them hooked and gain gain gain! They don’t care about us at all. They never have. So people like myself and others just want to go a day or two without pain and unfortunately it’s done by pain medicine. Wish I took care of my body at a young age because later in life these medical conditions dragged myself and other thru the mud. We 100% understand what you’re saying tho.

 

[Keif' Richards]

Believe me @KorruptedOne I feel for you. It's egregious what our people have been put through just to sell some pills. You like to believe in this world that people are not do callous as to get an entire country hooked on Opioids then to in the opposite direction and not prescribe those same treatments to those who really need it. No matter which way you turn it, the doctors and the pharmaceutical industry have made it completely clear that they care more about themselves than they do others. It's not as if someone is holding a gun to the head of the doctor's first-born son and demanding he write the scripts, no the doctor is writing the scripts because a normal, "good" life isn't enough. There needs to be a jet ski, fake tits for your wife and mistress both and season tickets to the Lakers.