Tryptamines 4-HO-MET high doses (over 40mg) experiences, please?

[Medevilx]

Tomorrow I will be doing 50mg of 4-HO-MET.

In my path as a psychonaut, I’ve found 4-HO-MET the most interesting substance so much, at least for me.

To be honest, 4-HO-MET alone did not do much for me. I tried 10mg (didn’t feel anything at all), 20mg (some light buzzing, but not impressive at all), 30mg (started to feel some psychedelics effects) and finally 40mg (OEV’s and an interesting little headspace).

30mg/40mg are supposed to be decent doses, and some people have tripped ball with these dosages, but that is not my case.

The good thing is that, since my two first experiments were really underwhelming, I vaped some weed trying to enhance the experience and then the trip become AMAZING. My best psychedelics experiences comes from the 4-HO-MET+cannabis combo, though my initial idea was not mixing any substances.

At 20mg and 0.5gr of cannabis I had a really wonderful experience. Same thing with 30mg+0.5gr cannabis and 40mg+0.25 cannabis. I got into a mind void where reality was gone and had a great mind trip with lots of realizations about ego, self, and how the mind works.

I’d like to know if any of you are experienced users of 4-HO-MET on doses over 40mg.

I’d like to try a 4-HO-MET dosage that is high enough to get me where 30mg+0.5gr of cannabis took me, and see the potentially of 4-HO-MET by itself, leaving cannabis out of the equation.

I don’t know if 4-HO-MET has enough magic to take me where I was taken when mixing it with cannabis, but I’m suspecting it is my ideal substance to take me where I want to go. Headspace, introspecting, disconnecting from reality, getting deep in my mind, into that void of cosmic space where only the mind exists.

Any 4-HO-MET experienced in these doses can tell me your impressions?

Thanks in advance!

 

[Opana313]

I guess I should google it but what exactly does it compare to? More of a low/medium dose of shrooms sayyy 3.5grams? At the 40mg and cannabis? Or more visual on the 5-6gram spectrum?

Or is it more energetic like low dose or one blotter hit of lsd? Idk if I've had any analougs or not so I just figure it's the real deal..

Also what's the come-up, peak, afterglow overall duration?

More importantly I feel my psychedelic dealer doesn't have this in his arsenal, definitely new to me.

 

[Arnold]

60mg just gives me a mild trip.
Enhanced music appreciation and just changes of colour perception. Zoplicone_bandit described it perfectly 'cartoon like colours'
Nice dosey feeling when combined with beers and weed.

 

[Arnold]

I guess I should google it but what exactly does it compare to? More of a low/medium dose of shrooms sayyy 3.5grams? At the 40mg and cannabis? Or more visual on the 5-6gram spectrum?

Or is it more energetic like low dose or one blotter hit of lsd? Idk if I've had any analougs or not so I just figure it's the real deal..

Also what's the come-up, peak, afterglow overall duration?

More importantly I feel my psychedelic dealer doesn't have this in his arsenal, definitely new to me.

Afterglow totally not comparable to shrooms imo.
About 6 hour trip.

 

[Pfafffed]

I can only contribute that I've taken 4-Aco-MET once at 40mg, and that it was lovely. I staggered it in 4 doses. It's much more potent for me than for you, though, by the sound of it.

 

[negrogesic]

I've taken it up to 80mg.

However, I've noticed that the relatively strong visuals that occur with 4-HO-MET start to lessen significantly after the first few times. The first time I took it at around 28mg, the visuals were very pronounced. I remember looking at the Roku remote, the looked at the wells, and patterns of the remote buttons were superimposed on the walls, everywhere, very clearly.

In anycase, 80mg is strong. The visuals returned, but were different. I remember looking at the clouds and they were dancing around in the sky.

Another time I took 70-80mg of 4-HO-MET plus another ~350mg of 4-AcO-DMT. I wound up in the hospital, convinced I was going to die. It was the weirdest feeling. As if I knew I was dying. Perhaps given the extreme dose, it mimicked what occurs during pre-death endogenous DMT release, because it was the most uncanny feeling. Like my body "knew" i was dying.

Of course I wasn't dying. My blood pressure was in the hypertensive crisis, something obscene like 210/180 (and that was after taking like 10mg of etizolam). I also felt like mentally I had ventured "too far" out there, and thought that if I recovered, I would require weeks in a psych ward trying to reintegrate myself back into this reality. So after some hours I wound up in the hospital and was released 6 hours later. Totally fine and clear headed.

Whats interesting, is that despite the extreme dose, the trip wasn't even that interesting. I entered some weird dark cathedrals, and then got sucked into a sea of black and white swirls, which felt quite terrifying and revolting. Kind of like this:



But as an opened hallucination, it was blinding. But the part where i felt like was about to die, I had a moment of clarity, and was saying goodbye to my girlfriend.

Otherwise it was quite uninteresting. I very much regretted it.

The time I ate a 500mg+ rock of DCK (O-PCE contaminated, i later discovered) with zero dissociative tolerance (my first time trying DCK) was also horrifying, but the visions I had were so interesting that I actually don't regret taking it. I would never do it again, was high for days and took me weeks to recover. I had odd urges for weeks, like to walk into moving traffic, a desire to smash things etc. But the visions I had were mind blowing, one where I was sucked into the womb and I was able to recall being an embryo, where I realized that we were all omniscient, eternal beings knowing all the secrets of the universe, and forget it all when are born. But i was for a moment that eternal being, and was able to rise far above the earth and witness the mechanics of the universe.

Not that I believe that, but it was quite impressive. The vision was either a) true or b) I have a good imagination

 

[Medevilx]

I’ve noticed that you can feel the potency of the substance and have a better idea of the dosage effects when meditating in total darkness, or with nice tripping music.That’s when you face the headspace of the substance, which is what I love.

 

[Ismene2]

Really depends on the quality of the synthesis. The original 4-ho-met was staggering - you were up dancing, euphoria off the charts.

But the shit synthesis 4-ho is a completrly different drug. Too much nausea to move so you are laid down most of the trip.

 

[Medevilx]

Really depends on the quality of the synthesis. The original 4-ho-met was staggering - you were up dancing, euphoria off the charts.

But the shit synthesis 4-ho is a completrly different drug. Too much nausea to move so you are laid down most of the trip.

The one coming from a well known european laboratory is very good, no nausea AT ALL

 

[Esperighanto]

The one coming from a well known european laboratory is very good, no nausea AT ALL

I really doubt that these differences are coming down to the synthesis of the compound, do you have any evidence of how something like this could happen? It reminds me of people talking about acid feeling "clean" or not, as if LSD is different from LSD somehow based on vibes or some other goofy shit, and it's always the 65 year old burnout on a jam band lot trying to convince me it has to do with elements of chemical synthesis they just don't understand.

 

[Ismene2]

I really doubt that these differences are coming down to the synthesis of the compound

What else could they be down to? The colour is usually different too - the good stuff is white, the shit stuff is grey. Presumably there's step that the people making the grey stuff arn't doing. Difference between acid and 4-Ho is the dosage is an order of magnitude difference which means any impurities are a lot more likely to cause nausea in 4-HO than they are in acid. Dr Seuss is massively different to any other acid.

 

[Esperighanto]

What else could they be down to? The colour is usually different too - the good stuff is white, the shit stuff is grey.

Without trying to separate out contaminants, or optimally running this through GC/MS you simply can't know. You could try purification methods like how people acetone wash speed, but I really suspect that's going to be a pain in the ass for metocin. My guess is that it has to do with aging or being kept in less than optimal storage conditions, as 4-HO-tryptamines are notoriously vulnerable to degradation over time of poor conditions and it's also common that they change color as a result. Past that though, I'm not sure, I just also find the concept of leftover synthesis by-products really unlikely.

There might be unreacted 4-HO-Tryptamine that didn't get reduced properly, and there might also have been overreaction with whatever the ethylating agent was leading to contamination with 4-HO-DET. These might be able to be analyzed if somebody is REALLY talented with a flash chromatography setup or thin layer chromatography if they're really good at it too, but I'm not positive that could be done given how similar these molecules are.

 

[Ismene2]

Without trying to separate out contaminants, or optimally running this through GC/MS you simply can't know. You could try purification methods like how people acetone wash speed, but I really suspect that's going to be a pain in the ass for metocin. My guess is that it has to do with aging or being kept in less than optimal storage conditions, as 4-HO-tryptamines are notoriously vulnerable to degradation over time of poor conditions and it's also common that they change color as a result. Past that though, I'm not sure, I just also find the concept of leftover synthesis by-products really unlikely.

There might be unreacted 4-HO-Tryptamine that didn't get reduced properly, and there might also have been overreaction with whatever the ethylating agent was leading to contamination with 4-HO-DET. These might be able to be analyzed if somebody is REALLY talented with a flash chromatography setup or thin layer chromatography if they're really good at it too, but I'm not positive that could be done given how similar these molecules are.

I only ever got the white 4-HO and 4-aco in the very early days of it being available in the UK - the first batch of grey 4-HO was like a different drug. Within an hour I was up dancing on the white 4-HO - on the grey stuff you're laid still for hours in case you vomit. The grey stuff is all that's been available in the UK for 2 or 3 years now.

 

[Esperighanto]

I only ever got the white 4-HO and 4-aco in the very early days of it being available in the UK - the first batch of grey 4-HO was like a different drug. Within an hour I was up dancing on the white 4-HO - on the grey stuff you're laid still for hours in case you vomit. The grey stuff is all that's been available in the UK for 2 or 3 years now.

Interesting, I'd love to see the results of a sample of both run through mass spectrometry. I suspect LC/MS might actually be needed bc the compounds might break down too much in a gaseous state. Regardless, the color of a drug is rarely an indicator of anything significant.

 

[Ismene2]

Interesting, I'd love to see the results of a sample of both run through mass spectrometry. I suspect LC/MS might actually be needed bc the compounds might break down too much in a gaseous state. Regardless, the color of a drug is rarely an indicator of anything significant.

Yeah but it might be an indication that there was a different lab working at the beginning making the white 4-H0. And seeing as the white stuff vanished after that initial batch maybe it was more expensive or needed more skill to make the white 4-HO.

 

[Esperighanto]

Yeah but it might be an indication that there was a different lab working at the beginning making the white 4-H0. And seeing as the white stuff vanished after that initial batch maybe it was more expensive or needed more skill to make the white 4-HO.

It's possible that there's a quality difference, I suppose I'm kind of thinking "in a vacuum" by assuming both batches have been recrystallized to optimize for purity. Serotonergic psychedelics just vary so intensely from experience to experience in general, iirc a study even found low doses of methylphenidate and DXM were indistinguishable from low doses of serotonergics. When I say low I'm talking threshold low, where you can barely tell there's something going on but you can feel something.

 

[iom]

Tomorrow I will be doing 50mg of 4-HO-MET.

Did you ever get around to this? Did everything go ok?

 

[negrogesic]

I had white 4-HO-MET that wasn't as good as tan, so color isn't always the best indicator.

Just ask John McAfee!

 

[Shinji Ikari]

The only 4-ho-met I've ever had has been grey and purchased in the UK, and for the last couple of years so far as I know there's only been one domestic dnm vendor stocking it.

In all likelyhood it's the exact same stuff lsmene is saying is shit (we don't exactly have a thriving RC market here). It's never made me nauseous, or immobile. It's my go to gig drug, very energetic and extraverted.

Different physiology, or different expectations? Who knows...

 

[Ismene2]

The only 4-ho-met I've ever had has been grey and purchased in the UK, and for the last couple of years so far as I know there's only been one domestic dnm vendor stocking it.

In all likelyhood it's the exact same stuff lsmene is saying is shit (we don't exactly have a thriving RC market here). It's never made me nauseous, or immobile. It's my go to gig drug, very energetic and extraverted.

Different physiology, or different expectations? Who knows...

What kinda dosage do you take? I used upwards of 100mg so maybe Im more liable to feel the effects of a shit synthesis.

Just going on the first stuff I had - that was white and I was dancing for hours. Its been so long since I had that - at least 3 or 4 years. The grey shit is like a different drug - never any dancing. It was my fave drug but the grey stuff ruined it for me. There is someone selling white 4aco again so i might try it again. Stupid price now tho - I cant face paying £175 for 750mg.