Opioids 300mg Tramdol Safe for first time? (Urgent!)

[Zombie Pharmacist]

Is 300mg Tramdol Safe for the first time?

Hey guys, is it safe to take 300mg of tramdol for your first time? I recently gave a friend some 150mg capsule and gave him the run down on safety (don't take more then one, don't drink, etc) but then he goes and takes two. Will he be alright? As far as I know he doesn't have any tolerance to opiates. Thanks!!

EDIT: I should add he's very experience with most other drugs like MDMA, Cocaine etc.

UPDATE: Turns out he actually took 5 (750mg). He seems alright though, just very relaxed. Although I was far from happy about it.

 

[King-Anubis]

I'm don't know much about tramadol so I can't say the following with any authroity, but as it's urgent I'll respond. Personally I think he'll be fine. 300mg of tramadol is equal to about 30mg of morphine, which is high but otherwise fine. He could probably get away with a few drink on top of that too (I say this because if he won't listen to your dosing advice, I doubt he'll listen to your alcohol advice.) If he's experienced with MDMA and the likes then the euphoria aspect shouldn't phase him.

Again, I don't know much about this so I'd wait for other answers.

 

[CrazyC]

I can't NOT post a reply when I see a post about Tramadol safety anymore.

I have posted about Tramadol causing my seizure ad nauseum, but it scared me that much. I am a veteran drug user and I have high opiate/benzo/pretty damn much anything tolerance, yet I seized on 300 mg of Tramadol. It was a horrible, horrible thing.

Basically for me, Tramadol is something I would NEVER fuck with if I had to do it over. It doesn't mean it can't be safe for others, but I learned that lack of harm with a previous dosage does NOT guarantee a safe experience in the future.

Please be careful, both you and your friend.

Peace,

C.

 

[Zombie Pharmacist]

Thanks guys - I did warn him about the seizure risk as well (which is why I said no more then one) but I guess some people never listen. I personally have never taken it myself as I take antipsychotics which lower the seizure threshold so I gave them to him instead. It sounds like he should be fine though, beside the seizure risk, which is a huge relief. I was (and am) really worried about him at the moment. He's with a bunch of friends so I'm hoping they'll keep an eye on him. Thank again.

 

[King-Anubis]

Five! Even ignoring the massive seizure risk at that dose, 750mg is pushing it. He's lucky that tramadol is a relatively mild and stimulating opiate, as the equivalent dose in, say, morphine or oxycodone could kill someone without tolerance with a low 'overdose threshold'.

 

[mastab423]

A friend of mine took 200mg with no tolerance and was fine. He just giggled and laughed. I used to take 400-500mg when I was young and stupid. It's not a very strong opioid, but like everyone else is saying, there is the issue of seizures. While I was fine, everyone's seizure threshold is different. He won't stop breathing from being overly sedated, but he could have a seizure if he has a tendency toward them. Maybe look up some things to do in case someone has a seizure so that you're prepared to help him. It seems like he should be okay though.

 

[pasha]

Tramadol seizures, according to several studies, are not dose dependent. Which means whether you take 50 milligrams, 400 milligrams, or 1000 milligrams the incidence of a seizure is almost equally likely. The most common dosage range to induce seizures however was concluded in one study as between 500-1000 milligrams to much a more significant degree than the 3000-4500 milligram range.

There's a good possibility your friend will be alright. Just make sure he doesn't take anymore tramadol, and if he exhibits any signs of jerking, cognitive deficits, motor impairment, or confusion, take him to the emergency room, or call emergency medical services.

 

[brutus]

Try the search engine.