illuminati boy
Bluelighter
Acute or chronic short-term memory effects? This difference between the two is not trivial.
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N&PD Moderators: Skorpio | someguyontheinternet
yaesutom said:Man i'm sorry but what bullshit!
Can't tell the difference between them?
Why make all of them?
I'm sure it may vary between SOME people, but not most...
specialspack, how many different psychedelics have you tried yourself?
Oh really? ok fine fine, double blind test, but have you read many trip reports? why are they often so so similar for a given substance, and what makes any of you think the 5ht2a receptor is just some .. simple "on/off" switch??
I'd think most of you would know way more than me about the structure of just this receptor alone, but i know an "agonist" doesn't just mean "on/off" like some simple light switch!
Even if you blocked every receptor BUT 5ht2a i am so positive DMT would still do what DMT does, and most psychedelics would do *most* of what they do without even touching other receptors (maybe potency differences and other minor things related to the other receptors like 1a 2c etc).
I'm curious how often some of you do trip, and on what variety of substances, and what you typically do on a 'trip'? Do you ever sit and think or look/read about all this stuff while tripping? Look at a picture of a computer generated 5ht2a receptor and any info you can about it, trippin' BALLZ and just.. think about it..
just wondering..
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later later
Oh really? ok fine fine, double blind test, but have you read many trip reports? why are they often so so similar for a given substance,
specialspack said:Look... what is the most important componant of psychedelic experience? Set & setting. Do I really need to argue for the power of the placebo effect on this forum?
Why do you think? Could it be because people read trip reports and then their expectations are set?
As Bilz0r says, some people are probablt good at telling the difference between different drugs. Sometimes the clues are obvious - duration, excess nausea, the difference between tryptamines & PEAs etc. I'd even say I was pretty good at telling apart the drugs that I've sampled before. But I don't doubt that my confidence would be misplaced in a blind taste test, or even worse when taking a substance that was misrepresented, when dealing with a group of similar drugs (eg 2C-x).
For the record, I have never tried any of the DOx series. But I have done plenty of other psychedelics, and I know that one experience varies to the next on the same drug, due to set & setting.
And do I need to remind you of the incident of the DOC contaminated with 2C-I that everyone was raving about, and just couldn't believe was contaminated because they thought they KNEW what 2C-I was like?
I'm sure that there are differences between the DOx series, but until someone does a proper double blind test, then I remain skeptical that these differences influence an experience by an order of magnitude greater than:
a) individual brain chemistry
b) expectation of the effects
ie - set & setting.
I'm sure it seems to many of you that you can tell the difference between them. There is, however, a huge body of experimental work that shows just how often people are wrong when they ascribe certain beliefs etc to themselves (Rensink's work on attentional blindness, Libet's on the illusion of conscious control of action... etc etc)
Ximot said:just a thought on the perceived differences of typtamines or phenethylamines... as I have always liked my drink I can vouch for the fact that, even though the various alcoholic beverages all contain ethyl-alcohol, they tend to have different buzzes. As psychedelics all make you "trip", all alcoholic drinks will get you "drunk" -- but the beer buzz is very different from the red wine buzz. White whine is a different story altogether. And champagne. Tequila is different from gin. Vodka again has a different vibe. It's true!
I can only speculate about the reasons ... of course the key ingredient in all those is the same chemical - alcohol - but maybe the alcohol in combination with all the co-factors in the drink also bind to receptors in different ways? Or maybe it's just the body that's affected differebntly - and we all know how body affects mind...
Kinda unrelated, this, maybe, but your discussion above reminded me and I think it is somehow the same sort of thing.