Search results for query: psilocybin

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  1. red22

    Phenethylamines Using mescaline as a substitute for DMT in ayahuasca

    i’ve tried this combination and it had no real overlap, they dont potentiate each other. 2c-b is only potentiated by mao-B inhibitors (see the mescaline page on wikipedia), so not that much point to it The fear over this combination is overexaggerated especially in the case of small doses...
  2. red22

    Pharmacology Does JRT get its nootropic effect from tryptamine?

    ...resulting in a compound that retains neuroplastic effects while minimizing hallucinogenic properties." Sounds like a cross between psilocybin and lsd Exactly—that’s a pretty good intuition. 😄 Structurally and pharmacologically, JRT does resemble a hybrid of LSD and psilocybin in a...
  3. Esperighanto

    Requests Thoughts about Metocin 4-HO-MET ?

    ...whatsoever. The visuals are sort of "cartoonish" and "artificial" seeming to me, in a way that's more similar to 25B-NBOMe/25B-NBOH/Psilocybin containing fungi than it is to any other psychedelic, at least for me. Therapeutically I consider metocin virtually useless, though in combination...
  4. O

    Positive On a positive note.....synthetic psilocybin-Metocin

    I can without a shadow of a doubt share your experience of psilocybin being the medicine needed to get out of a med-withdrawl -paws- any depressed shit that leads me backwards, was erased. I think it sustains because you integrate the experience and also preparing for the next, is HIGHLY...
  5. red22

    Lysergamides LSI, Ancient LSD, Secret of the Eleusis Kykeon and Vedic SOMA

    ...1.5 mg ergonovine base, ingested in a glass of water. 13.00 h: slight nausea, same effect as I have experienced always in my LSD or psilocybin experiments. Tired, need to lie down. With eyes closed colored figures. 13.30 h: the trees in the nearby forest seem to live, their branches moving...
  6. perpetualdawn

    Nootropics which psychedelic would induce the most neuroplasticity?

    ...from psychedelics claim is clinically well observed and measured now, I wouldn't say it's vague or inconclusive any more. "Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo" https://pubmed.ncbi.nlm.nih.gov/34228959/ "Psilocybin desynchronizes the...
  7. SuperPsych

    Tryptamines The Big & Dandy 4-HO-MiPT Thread - 2nd MiPteration

    I agree with 4-HO-MIPT being on par with psilocybin in terms of introspection. They both tend to focus on different things and they go about it differently. 4-HO-MIPT is pretty interesting in the fact that even when the introspection gets a bit intensive, the vibe still remains positive; whereas...
  8. 4DQSAR

    Nootropics Mushroom Gummies

    https://www.theguardian.com/science/2026/may/05/magic-mushrooms-psychedelic-changes-brain-anatomy-psilocybin I thought this might interest you. Sadly, @fastandbulbous appears to be MIA but they made quite an interesting point in that such fungi convert tryptophan into 4-OH N,N-DMT (psilocin)...
  9. M!$TER-ED

    Positive On a positive note.....synthetic psilocybin-Metocin

    I appreciate your response. I don't know how popular Metocin is globally, but I advocate for it in my trusted circles.
  10. emkee_reinvented

    Bluelighter's guide to soul food - What is the best thing to eat when you're high?

    ...totally. Mine uses minimal. But a time effort and setting the clock. And working with string s under influence of psychedelic s not advised for beginner s. Not that i am, atm, just imagining. Squeezing Orange s not something to underestimate or take lightly. On Psilocybine containing mushrooms.
  11. Juicewrldfan

    Ethnobotanicals Psilocybin, synthetic and BUSPIRONE safe?

    Is it safe to take psilocybin synthetic with Bruce Brown already in your system taking this morning 10 mg
  12. F

    RCs Do any good legal highs still exist ??

    I hate bad the scamming has gotten you dont know if your getting the chemical you paid for you almost have to test everything to make sure.
  13. pupnik

    Nootropics which psychedelic would induce the most neuroplasticity?

    ...rather than what we sustain later in life when we enjoy psychedelics. Among Psychedelics, the salvia divinorum path to strangeness is quite extreme, although psilocybin and LSD are sufficiently strange to produce altered mental formations, and neuroplastic muchness however you interpret that.
  14. TheLightBringer

    Tryptamines Mushroom mini-sessions and microdoses

    Yes the dosage is quite different in psilocybin and MDMA which does give me hope, Im unsure of the safety profile of 2C-B regarding 5HT2B agonism. Other phenethylamines do posses quite the affinity for 5HT2B. I think everyone should be aware that Alexander Shulgin who trialed many tryptamines...
  15. M!$TER-ED

    Changing to COBENFY

    ...was able to stop taking all antidepressants and antipsychotics, perhaps by taking Metocin unscheduled psychedelic similar in experience to psilocybin. I do not claim Metocin is completely responsible for my ability to stop taking these medications, however, coincidentally, I no longer need...
  16. Syntherize

    Tryptamines Ways to potentiate my 4-Pro-DMT?

    Combining MAOI’s with tryptamines or any other monoamines is very dangerous, risky, and foolish. I say stand down and simply enjoy what you have.
  17. BeefExtreme

    Hello. I am Beef

    I tried the synth mesc and honestly didnt get much out of it. Its insanely expensive. Never tried the synthed psilocyben though. Id be inteterested to try it of course, if only to ecperience the chemical im absence of the other usual suspect alkaloids in shrooms. I suspect some of those...
  18. deepnbeeper

    Tryptamines Shelf life of mushrooms?

    How long will mushrooms (psilocybin) last at room temperature in a dried out state?
  19. streaM Freak

    It seems most at people are ignorant when it comes to drugs

    Seroquel, in my experience, helped with depression simply because it greatly reduced my irritability. It doesn't specifically target the serotonin receptors. And for dopamine, it doesn't increase it, it actually does the opposite. So if you are not manic, psychotic, or having sleep trouble...
  20. Dextro .45

    Drugs What drugs did you do on christmas?

    Methadone 100 - 125mg Ritalin (Methylphenidate) 50-70mg IR Avizafone (Pro-Diazepam) 60-80mg (RAPID acting 30-40mg of IM Valium) reaching C-Max in 0.5h Psilocybin / penis envin Ethanol Gin 2.0z per drink Cannabis
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