Search results for query: SSRI and cocaine

I never had any desire to do meth or cocaine until I tried IV injection, and the rush was what I loved. However, I disliked the actual feeling, beyond about the first hour on meth and the first 5 minutes on coke, and wanted heroin or benzoes or alcohol, if nothing else was available to come down...

Yes, I have personally battled with cocaine use for many years. What happens is you deplete yourself from serotonin as well as dopamine so a couple of days later you will want to use again a lot more. Typically the next day it is normal to be set on quitting, but the urge will come a couple of...

Absolutely no idea where to post these questions; hoping someone with a similar experience or some knowledge from related experience might chime in. I have been a casual recreational drug user for many years. The past couple years I have been big into cocaine, with the occasional whippits or...

Yes. There are a lot of dangers associated with the drugs that you've mentioned. SNRI's may or may not blunt the subjective effects of other drugs in the same way that SSRI's do, but there's no hard evidence that I possess that makes evident why this might be. The Duloxetine (Cymbalta) and...

Wellbutrin is a dopamine (and norepi) reuptake inhibitor, just like Ritalin/methylphenidate. Amphetamines and cocaine use the transporter to do what they do, so combining them should be just like taking E on Prozac. I haven't tried it though. There's no reason to think it potentiates--I can't...

SSRI's selectively block the re-uptake of serotonin. MDMA and cocaine both block the re-uptake of serotonin. MDMA also releases serotonin. please don't use these drugs while on antidepressants, it is discouraged because it is simply not good for your brain.

I've been drinking so much juice the last three days! It's like I just want to cleanse my system so I bought a bunch of raw juices from Beyond. They're delicious! I definitely need to get in with both my psychiatrist and my general practitioner. On top of the cocaine withdrawals, I've been...

I am trying to find something that is to Modafinil what Xanax is to cocaine. I.e make it smoother and calmer and much better. I need o potentiate the experience and give balance. From my few experiments benzos just cancel out the Modafinil so does eszopiclone and zolpidem. I've even tried an...

I don't really get this. What I heard from my psychiatrist, is that Dopamine was not considered as an important neurotransmitter in depression, which seems completely stupid. Dopamine is responsible for the feeling of pleasure and motivation. It realises your anxiety and fear (if properly...

Wait, are you suggesting that this compound would be empathogenic? Because I was under the impression that while noradrenaline-dopamine reuptake inhibitors and noradrenaline-dopamine releasing agents can both work as stimulants (ex.: MDPV and methamphetamine both being potent stimulants)...

OK so my buddy has had a history of seizures he believes to have originated when he was working with and huffing Medical Nitrous oxide (5- 100 lb tanks) for about 3 years ...resulting in a horrible B-12 deficiency, At 17 he was of Diagnosed with Polly-Neuropathy affecting mainly his...

Hey merseyside8 and I apologize that I haven't had a chance to formally welcome you to the community, so, WELCOME! As I tell all new folks, please familiarize yourself with the forum guidelines before creating new threads or even responding to existing ones. We do have rules and expectations but...

NOT DONE YET, WILL BE PRETTIER, SHORTER AFTER DRUGS NOW PUBLISH CAT-PROOFS It's like people know I have nothing to do on a Friday night but eat cold leftovers with my dog and type on the internet (there is also a cat. Not that one, no). First thing to clear up: you are not "low" on serotonin...

The Neuroanatomy of a Psychedelic Trip: The Basics by Zeus Tipado | Healing Maps | 20 Oct 2021 There’s a good chance that anyone reading this article has genuine interest in psychedelics. And there’s an even greater chances you’ve already done psychedelics. And now you want to know...

I used cocaine for a year straight up to three times a week. I also messed around with Molly. I ended up overdosing on Molly last May and since then stayed clean of everything. Last summer, I was fine. The only thing I did was drink. Around October I started noticing small moments of anxiety but...

They are only long lasting because of loss of ester functionality. Bridge the piperidine with the aryl ring with an ester to reduce half life. Compared to cocaine itself, the syntheses of these piperidines would be much, much easier. They look quite reasonable to synthesise and the data for...

Head pressure more than a headache. No pounding, just a feeling that maybe I'm wearing a motorcycle helmet or a cap that's way too tight. Mostly across the forehead and top of the head. It seems to correlate a lot with my brain fog. The more head pressure, the greater the fog. My only real eye...

How many days a week/doses per day etc does one need to take Adderall or Dexadrine to get physically dependent? I have not experienced physical dependence on adderall it is from my experience mostly if not entirely psychologically motivated. While physical dependence and withdrawal occur with...

I'm a 33 year old male. It's now 3 years since I've last taken SSRIs (escitalopram back then. but I have taken a bunch of others too, eg. paroxetine, fluoxetine, venlafaxine, citalopram etc). When I started taking SSRIs my whole sexuality was wiped away. My sexuality never recovered. It feels...

I am interested in empathogens, however their neurotoxicity worries me. The metabolites and dopamine hypotheses for MDMA's neurotoxicity seem to try to put it as not something inherent to MDMA and triple monoamine release, rather some misfortunate particularity. Though hitherto there seems to...