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Kratom Kratom Megathread V.2

How frequently should one dose if he's just concerned about avoiding bad withdrawal
 
“We published the first study showing rats will work to get 7‑OH,” he said, noting that animals repeatedly self‑administered the compound — “the standard test for a drug’s addiction potential.” By contrast, “They wouldn’t do it for mitragynine at any dose we tried.”



Speciociliatine is a stereoisomer of mitragynine that may have more potential than mitragynine:

Metabolism of Speciociliatine, an Overlooked Kratom Alkaloid for its Potential Pharmacological Effects. Kamble, S. H., Berthold, E. C., Kanumuri, S. R. R., King, T. I., Kuntz, M. A., León, F., Mottinelli, M., McMahon, L. R., McCurdy, C. R., & Sharma, A. (2022). The AAPS journal, 24(5), 86. doi: 10.1208/s12248-022-00736-8


i got a lot better effects from the high 7oh extracts from █████████▊ and its about 1/7 the price per dose. but again, 7OH is just sedating, which it doesnt sound like OP wants. of everything i’ve tried, their high speciociliatine extract has had the most euphoric effects

daddyfatknuckles, 2024-03-08, re: 7OHM-Z


i think the most pleasurable kratom experience i’ve had was mixing high Speciociliatine extract (30%MIT/15%SP) with high 7OH extract (25%MIT/1.5%7OH) - these powder extracts are relatively cheap, for extracts

daddyfatknuckles, 2024-02-15, reddit
 
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