Phenethylamines 2c-b - can I get a hell yeah?

[Esperighanto]

I think taking 2C-B so frequently is not a good idea. There are a handful of (anecdotal) reports of young people running into cardiac issues after frequent longterm use and the pharmacology of 2C-B certainly implicates it as a risk factor. So I think from a harm reduction standpoint I do not think it is advisable. I also think I'm seeing some sort of trend towards higher doses becoming more prevalent, but I may be biased. I think it is only a matter of time before someone susceptible pushes it a tad too far, sadly. Personally I did not see much value in the higher doses (say 40 mg oral or 25 mg rectal), but I've only tried it a handful of times. For me a solid 24 mg dose orally gives all I need, but I often take only around 20 mg and it is fully developed with all that I could ask for at this dosage.

To me the therapeutic value of 2C-B is mainly that it serves as some sort of refuge from the stressors of life, forcing a change in perception enhancing the look at what's good. It is very powerful at that and even in sober reality I can think back to 2C-B and whenever I'm low I'm able to remember the great times I had on 2C-B. It's like "hey friend, life isn't so serious, don't beat yourself up" and brings a smile. Yet it is not an artificial escape and to me, entirely non-addictive and self-regulating. I find it hard to overuse, but I've certainly noticed a tendency in some people to be a bit too légère with it. A mountain of 2C-B to snort from every day sitting on a table readily available is pretty high in my personal list of "things not to do". But that's just my opinion and no offence meant (I think you wouldn't take it as offensive anyways, Esperighanto).

I would like to hear your opinion though on why you think such frequent dosing offers advantages in comparison to regular trips (say every 2 weeks or every month). I've tried tripping multiple days in a week with 2C-B, or even going for another round of 2C-B (never really redosing, but going for a separate trip after the first ended), and while there is not necessarily tolerance going on, there is some kind of blunting. It may have to do with being exhausted from the previous trip or from having a bad conscience of tripping too frequently. Psychedelics are more anti-drug (even to themselves) for me than the D.E.A. could ever be

Yeah, we specifically were using 2C-B daily when covid fucked up the supply chains hard enough to where we could not access any of our psychiatric medications (bupropion, lamictal and aripiprazole), and daily administration of 2C-B (or 3-MeO-PCP, or 3-HO-PCP) could remove any of our needs for those medications. Once we had access to our standard prescription medications again, the 2C-B use became far more sparse. My primary use for 2C-B after that period was taking 8-12mg doses in the morning orally if I was in a super depressed headspace, much like ketamine or LSD it's great at breaking me out of cognitive ruts.

 

[placebonaut]

In this day and age reliable vendors are a thing of the past; all the good ones either got busted or retired. Allot of changes came to the drug laws in the Netherlands. I wouldn't trust any of the connects these days.

less out there but not sure that's the case in my experience in the past 1-2 years, even in the UK with the state of our market there are decent vendors out there, you just need to do your research

Yeah, we specifically were using 2C-B daily when covid fucked up the supply chains hard enough to where we could not access any of our psychiatric medications (bupropion, lamictal and aripiprazole), and daily administration of 2C-B (or 3-MeO-PCP, or 3-HO-PCP) could remove any of our needs for those medications. Once we had access to our standard prescription medications again, the 2C-B use became far more sparse. My primary use for 2C-B after that period was taking 8-12mg doses in the morning orally if I was in a super depressed headspace, much like ketamine or LSD it's great at breaking me out of cognitive ruts.

interesting.

did you notice much increase in tolerance during this time?

 

[Esperighanto]

did you notice much increase in tolerance during this time?

Absolutely none.

 

[placebonaut]

Absolutely none.

really interesting.

I'm liking my 2cb experiments right now, don't plan on taking it more than once a week (likely once a fortnight).

I can also see a place for regular "ketamine therapy", think it really helps to ground me.

I'm likely to alternated between 2CB, ket, and MDMA I think with 1-2 weeks break between each, a bit of soul food.

 

[Ismene2]

I've been pondering microdosing psychedelics for a while and was considering if 2-CB could be a candidate, this thread's prompted me to finally do a bit of research.

general forum themes seem to call out that its steep response curve makes it hard to consistently microdose so you're either too low or too high (esp. when you consider tolerance builds), there's negative body load issues that offset the upside of the microdose - better dose bigger less frequently.

Think I'll save mine for treats and look at Psilocybin microdosing instead.

AI summary:-

I never noticed any steep response curve - I took one tablet, then two, then four - no change in the effects at all. I've no idea what they're talking about with the "steep response curve".

Zero bodyload and the best afterglow I've ever had. I think it would be perfect for microdosing because it's such a light psychedelic - more of a very gentle amphetamine and moodlifter/antidepressant

 

[Camomill]

I never noticed any steep response curve - I took one tablet, then two, then four - no change in the effects at all. I've no idea what they're talking about with the "steep response curve".

Zero bodyload and the best afterglow I've ever had. I think it would be perfect for microdosing because it's such a light psychedelic - more of a very gentle amphetamine and moodlifter/antidepressant

how much time passed between your redosing events?
The duration of effects ain't the longest with this substance, maybe you just prolonged the trip instead of heightening its intensity.

If you take 4 at once, it would be a completely different beast, i can imagine.

 

[Ismene2]

Various combinations - one first, then 2 a couple hours later, then another 3 a couple hours after that. Two first, then two an hour after that. Never noticed any steep response curve 2 was a bit stronger than one as you might guess.

 

[Camomill]

Various combinations - one first, then 2 a couple hours later, then another 3 a couple hours after that. Two first, then two an hour after that. Never noticed any steep response curve 2 was a bit stronger than one as you might guess.

take care and have fun

 

[JackARoe]

I also think the big and dandy's do not get enough love. I like info all in one area. I had posted a lot of HBWS and none of it did i put it in the big and dandy. Just a strangler thread that I can't find now. But I am tempted to start merging.

When I have some time I am going to try a minor merge.

@Ismene2 , you have had some big shoulders in the last 15 years. But I admit I too can feel the world shift for all of us when a drug (clean LSD, 4-ACO-DMT, and now 2C-B) comes into your landscape.

I went through a gram and a half of 2C-B in 17 years. Shared about 300 mgs. And still never did it more than a few times a year. It is amazing how even 15 mgs is healing.

 

[Ismene2]

If you take 4 at once, it would be a completely different beast, i can imagine.

I thunk it makes a difference on your first dose - so taking 4 isnt as comfortable, but once youve had the first pill I didnt notice much difference after that

 

[Esperighanto]

I thunk it makes a difference on your first dose - so taking 4 isnt as comfortable, but once youve had the first pill I didnt notice much difference after that

2C-B most definitely benefits from this approach of stepping your way up instead of jumping all the way up at once.

 

[placebonaut]

another dose today, not a crazy dose, had a bit of weed to give it a kick.

feel I got a bit of therapy from it which I wasn't expecting.

 

[Esperighanto]

another dose today, not a crazy dose, had a bit of weed to give it a kick.

feel I got a bit of therapy from it which I wasn't expecting.

2C-B sneaks lessons up on everybody quickly and by surprise, but trust me they are WORTH listening to, especially relative to goofier drugs for therapeutic contexts (ketamine especially in my personal opinion).

 

[placebonaut]

2C-B sneaks lessons up on everybody quickly and by surprise, but trust me they are WORTH listening to, especially relative to goofier drugs for therapeutic contexts (ketamine especially in my personal opinion).

definitely listened to it, I find ketamine quite therapeutic generally, are you saying that you think 2CB is more so?

 

[Esperighanto]

definitely listened to it, I find ketamine quite therapeutic generally, are you saying that you think 2CB is more so?

Yeah, the way that ket clinics IV people ketamine deep into a k-hole with no guidance right now is terribly ineffective.

 

[spypilot]

you indeed can get a hell yeah

 

[placebonaut]

Yeah, the way that ket clinics IV people ketamine deep into a k-hole with no guidance right now is terribly ineffective.

not really following things in the US that closely, are the clinics over there just slamming ket in to anyone who pays the bill without any kind of support or guidance? i.e. like "medical" cannabis anyone who wants it can come get some.

seems a bit irresponsible...and a big wasted opportunity for those who actually need therapy! I can see how lack of support would lesson the therapeutic value though isn't ket intrinsically therapeutic anyway?

Acknowledging my limited experience with 2C-B here, I'm not yet experiencing how 2C-B has more therapeutic value versus ketamine, the 2C-B insights were much milder and not at all like the intense epiphanies you get with ket.

How dose dependent is the therapeutic value of 2C-B? on the session I had some therapeutic value from I'd actually reduced my dose as I had nausea at higher dosage the previous time - still trying to find the sweet spot.

I'm pondering which direction I should take next on my little journey.....I enjoy Ket and can see value in doing it occasionally (love being connected to the hive mind), 2C-B seems like a mild hallucinogen and much closer to MDMA than to LSD (at least so far to me). I've had a heroic LSD dose, and don't really feel the need to go back to that sort of tangle (I might do lower dose LSD at some point but the duration puts me off a bit).

Going to keep playing with 2C-B, not sure if I should push the dosage up more or not though, I'm very much at peak physical sensory stimulation I can handle I think, but I'm not getting intense visuals, paisley patterns moving about type level, but no geometric patterns. Quite happy taking it at lower doses but not sure if I'm missing out by not upping the dose a bit more??

I've also got a few hillbilly mushrooms, going to give these a go at mircrodoses at some point to start off with.

also pondering mixing things, maybe ket + 2C-B or 2C-B + MDMA, not sure

 

[Esperighanto]

not really following things in the US that closely, are the clinics over there just slamming ket in to anyone who pays the bill without any kind of support or guidance? i.e. like "medical" cannabis anyone who wants it can come get some.

Yeah this is the current standard in the city I was living in up until about a year and a half ago, it's a fucking atrocity.

also pondering mixing things, maybe ket + 2C-B or 2C-B + MDMA, not sure

2C-B and MDMA are best friends. The night of my engagement we mixed the two with carisoprodol, 7-hydroxymitragynine and some kratom leaf (gives it legs). It was a fittingly euphoric combination for such a beautiful night.