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jwh-250

S

smitty823j

Bluelighter
Joined
Mar 3, 2011
Messages
75
Can you folks answer some basic questions.
Can it be smoked in a regular bowl? If so..can it be smoked alone or is it better on top of or under some plant material?
Is is active oraaly, sublingual or by plugging?
For whichever of these routes are active can you give me some dosing ideas?

Thanks
 
1. Yes, but it's better to just chase it off foil
2. Yes, Idk, Idk
3. Start small, to much and you'll freak out to the point you'll feel like your going to die
 
1. Yes, and I disagree with above poster, chasing smoke can be difficult and annoying. just put some powder on top of some ash in a pipe and put the flame near the powder (not on it). watch it melt and drag. after the powder all melts i find i can start to hit the bowl with the lighter directly and get good hits. i always had a MUCH easier time just doing this than trying to chase smoke off of foil.

jwh-250 is great and my favorite synthetic cannabinoid so far. it has a cleaner/less pronounced body feel than pot and doesn't make me need to sleep, its shorter (which i guess could be a con for you, but i like this), and maybe it's just me but its FAR more visual than pot for me. after smoking some pretty hefty bowls ive got CEVs that were better than low dose LSD, no joke.
 
I have no luck with doing things off of foil myself.
Any suggestions for a dosage on top of some ash or plant material.

as well as the success/dosing for the other ROA's I listed?
 
never attempted the other ROA's, smoking is the perfect ROA for it in my book. there's no reason to do anything else.

as far as a dosage, i really don't know, i just kind of put on a random amount because jwh 250 doesn't overdose easily for me.
 
I heared that JWH-250 is very weak orally, like 5x-10x more weak comparing to smoking. But please note that I haven't verified this info.
 
Long shot here, but someone posted a while ago an easy way to chase chems off foil. I believe it was one of dem PV goons
 
It seems to be quite similar to potent weed or pure THC in that the Ki (CB1) = 11 nM and Ki (CB2) = 33 nM. So yes it should make you trip like cannabis can.

But I'm not sure I know what you mean by the stuff, many JWH compounds are like that... although some seem to be primarily anxiolytic and/or analgesic.
 
I see varying reports as to its oral activity. Thus my question here.
I just perused the big thread and can find nothing about sublinqual or plugging.

Sounds like smoking is gonna be my first experiment with this. Thus far my thought process is 5mg for my first try.
 
Oral doses for some of these compounds is about double of what you would smoke but for other JWHs it is like 4 or 5 times that. It depends per compound and I don't know about JWH-250 in particular. It would be great to get a dosage table for these compounds for smoked as well as oral doses, and fill it.

If you have not read anything else about it before I suggest not eating more than a dose you get high off by smoking, just to be sure.
 
all the oral JWH reports i've seen tend to have a lot of variability. Even within the same person. However, this seems to be alleviated by dissolving it in vegetable oil or some other lipid. Definitely more reliable that way.
 
Dropping it in vegetable oil and then what? Smoking it? Eating it? Can't see how something would smoke in vegetable oil.... If you mean eat it....How would vegetable oil make something that is orally weak stronger?
 
Then eating it. Ever heared about oral cannabis recipies? Many cannabinoids(including JWH-250) are fat-soluble(and insoluble in water), thus (I think) they are required to be dissolved in fat/oil to be active.

I don't know the exact mechanism, so I can be wrong.
 
Solipsis said:
It seems to be quite similar to potent weed or pure THC in that the Ki (CB1) = 11 nM and Ki (CB2) = 33 nM. So yes it should make you trip like cannabis can.

But I'm not sure I know what you mean by the stuff, many JWH compounds are like that... although some seem to be primarily anxiolytic and/or analgesic.
Click to expand...

i just mean is jwh-250 the only synthetic canabinoid that causes you to trip? theres one in particular which i get really strong body trips from. i mean theyre seriously intense. here in ireland they were in a product called Red Eye, and also in XXXX (quadrouple x).
 
I have experience and success with oral JWH-018 and -081.

Sublingual on a mint carrier (infused via alcohol) was completely inactive at 5x the smoked dose.

Vegetable oil (olive, to be specific) was NOT a good idea. Dose is similar to smoking (5-10mg) but it takes WAY TOO LONG to kick in which leads to overdose situations.

If you want to do oral JWH, it must be in short to medium-chain fatty acids, like those found in milkfat or coconut oil.

Get one stick of butter, the real cow milk kind, and melt in a saucepan just as you would for making cannabutter. Keep the heat low and stir often. Don't burn it! Simmer until most of the water content has left the butter.

Add the appropriately-weighed dose of JWH. Figure 1:1 your average smoking dose, and PLEASE consider tolerance in this! Don't overdose your friends. Be sure to write down the actual dose used, and multiply by the number of squares you plan to cut.

Once the JWH powder is fully dissolved (only a minute or two of stirring) take the butter off the heat and make a box of brownies, substituting the butter for the oil that it normally calls for. Remember that the butter should be cool before you mix in the eggs, or you'll make a scramble instead of a cake :) Bake as directed, cut into the number of squares you wrote down, and enjoy. Personally I use the hot butter to make a whole tray of dark chocolate fudge, which yields about 100 bite-sized squares with 10mg of JWH each.

I have found that with this method (MILKFAT!) the effects come on strong around 40 minutes in just like a true cannabrownie, but the duration depends on the specific JWH used (018 is longer than 250). Interestingly enough, it appears to work even on a full stomach.

ALWAYS LABEL ANY CONTAINER CONTAINING EDIBLE DRUGS! Two or three of these properly prepared treats will directly lead to overdose situation (whitey out, nausea, bad trip, whatever happens to you on a CB overdose)

Oh BTW the reason for the milkfat is because short chain fatty acids are sent to the liver for processing by a different enzyme than the ones that do longer chain unsaturated acids. short-chain acids are metabolized very quickly into energy for the body, so the drugs dissolved in them will be more predictably distributed to the bloodstream.
 
Last edited:
allium said:
Then eating it. Ever heared about oral cannabis recipies? Many cannabinoids(including JWH-250) are fat-soluble(and insoluble in water), thus (I think) they are required to be dissolved in fat/oil to be active.

I don't know the exact mechanism, so I can be wrong.
Click to expand...

Not required. You can eat hash as-is, though it is a sort of fatty substance in itself. I can imagine that oil is a good carrier though, to help it sort of dilute and transport well. But it's not like it is not active whatsoever without the oil. ;)
You probably knew that but just to be clear.

You can't eat cannabis itself (weed) with very good effect because it is very hard to digest the plant material that contains the cannabinoids. It's like they are oils trapped in the trichomes if I am not mistaken.

I think for this same reason if you knead bubblehash when you make it, you could break open those cells and it comes out and becomes more oily. After that it actually bubbles / boils when you smoke it. But it seems to degrade faster as well since it is no longer protected inside those trichomes. But don't quote me on this, it was only told to me by a cannabis fanatic and I found it pretty convincing.
 
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