Long term opiate use causes physical side-effects that are mostly benign and short-term, ie. respiratory depression from opiates in combination with smoking tobacco or weed can make the lungs weaker and slow their natural cleansing processes.
But also, in hijacking the body's endorphin system, long-term opiate use can cause drastic changes in the ways that we become motivated or experience pleasure.
Depression and mania can be ameliorated by daily opiate use but so can creativity and motivation. These effects are different for everyone, but for those who rely on their creativity and motivation for financial stability or long-term mental health, opiates can and often do become a heavy burden.
It's wise to check your personality and mental health and assess the changes (if any) you've experienced since becoming physically dependent on opiates. It's almost always a challenge, ESPECIALLY if you're in pain every day, to decide whether opiates are working for or against you. At some point, the balance often seems to tip from the positive to the negative.