Opioids Defeating the new OC time release

[Lando138]

the original (popular) OC's only have an 8hr time release mechanism compared to the 12 hour time release on the OP.

its deinitely an improvement for those of us on PM seeing we'rw getting the right coverage (12hrs tr) instead of just 8hrs. it allows for peaks and troughs to be more consistent of the plasma concentration levels of the drug in your system.

I hate to take this off topic, but would you consider this to be the reason why so many people are saying they don't work as well as the OC's? By "people" i'm referring to the people on here who have said they take it for legit reasons and taking it orally and untampered. It seems like this could be the cause because its the same dose but spread out 50% longer, so it would definitely seem weaker to someone who is used to a quicker release. I also bring this up because i've wondered if this means that purdue might consider releasing stronger doses to compensate. There's been talk of people having to switch meds because of this and someone even said they were trying to organize a boycott. Either way, if these kinds of things happen enough purdue will for sure take a hit and i'm sure greedy corporate bastards won't accept that, and even though people are hoping this will result in them bringing back the old formula, i highly doubt that would happen because there would be protests from people who are actively against oxycontin in the first place and a media frenzy and also their contract with Ethex to distribute the old formula (if thats even still happening) and on and on. Not to mention what the FDA would have to say about that. BUT, i would think introducing higher doses of the new formula might be more "acceptable" for critics.

Alright sorry about the long post, i've followed this thread from the beginning and haven't contributed yet and i don't recall anyone bringing up these ideas so something to think about.

 

[HdoubleODeezy]

^ good point because the same amount (80mg) spread to release over 12hrs would release less per hour than one that is made to distribute all 80mgs over 8hrs..

so the old 80's released 10mg/hr
and new OP 80's release 6.66mg/hr

pretty close to half the amount, and i bet it feels like half to the people who take them also.

 

[mr.muncheez]

I hate to take this off topic, but would you consider this to be the reason why so many people are saying they don't work as well as the OC's? By "people" i'm referring to the people on here who have said they take it for legit reasons and taking it orally and untampered. It seems like this could be the cause because its the same dose but spread out 50% longer, so it would definitely seem weaker to someone who is used to a quicker release. I also bring this up because i've wondered if this means that purdue might consider releasing stronger doses to compensate. There's been talk of people having to switch meds because of this and someone even said they were trying to organize a boycott. Either way, if these kinds of things happen enough purdue will for sure take a hit and i'm sure greedy corporate bastards won't accept that, and even though people are hoping this will result in them bringing back the old formula, i highly doubt that would happen because there would be protests from people who are actively against oxycontin in the first place and a media frenzy and also their contract with Ethex to distribute the old formula (if thats even still happening) and on and on. Not to mention what the FDA would have to say about that. BUT, i would think introducing higher doses of the new formula might be more "acceptable" for critics.

Alright sorry about the long post, i've followed this thread from the beginning and haven't contributed yet and i don't recall anyone bringing up these ideas so something to think about.

THEY aren't LOSING any money, they are making money on BOTH formulas. However, it can't be discussed here any longer... but they are smart mother-effers...making money on the backend and their patents are rock solid.

I thought the 160's were discontinued because of the pressure from the FDA, or they were only available in very limited case by case basis, and not for take home..Hospital only? Maybe now, they will be able to start releasing those in take home scripts. Who knows what will happen from here on in.

 

[grafitti]

Short of it: it works, kinda. Long of it: doesn't seem to gel up much if at all, and there's more of a drip than just blowing straight OP, but it's not as much as a regular OC. Definitely works better than straight OP, but again not as good as reg OC. I'd say it's right in the middle between OP and OC in terms of overall effectiveness. Much better than blowing OP, and as close as I've gotten to it feeling like an OC. All I know is my pupils are tiny, and I kicked some ass in modern warfare 2...a sure sign that I'm properly opiated. Gonna experiment with using more MEK, as the stuff completely evaporates away leaving no smell or taste. In fact, you know your mixture is ready when you can't smell the MEK in the table spoon any more. Good luck and be smart!

not sure why this is so hard three or more people have done it with sucess if u read the threads , use a Dr. Scholz calius file to grind into a powder , make sure to get all the powder wet , let evaporate for a good 15-30 minutes , add a 30 if u can ,i am not thinking i am high i have been on oxy for over 10 years , plus when your pupils turn to pin points within minutes of doing this it is a good sign , do u think purdue would tell everybody let alone even try this , it does work ,i did it 4 days in a row , i am doing it again now because someone says it does not making me think i am crazy but i am not it works fine u need patience , powderized puff , though i am not sure if the m e k could affect u so i would not do this every day , just for a quick thing once in a while it does defeat the time release , no blue goo if u do it properly and u get high as a kite , its a thread about beating time release this works fine just be careful

 

[grafitti]

maybe should add this after it is dry , u do need to crush it again as it will be in larger clumps , this u just need a credit card whatever get it very fine , if there are a few larger clumps remove them , they will cause serious jelling , u want only the fine powder , u want it dry and fine , one missed piece of the uncontaminated oxy causes alot of jell so make sure all the powder is fine and u will have no problems it only takes 20 - 30 minutes ,i know thats an etirnity compared to old ones and it is a hassle but it does defeat the time release with no goo

 

[ihatepipes]

I tried the MEK method graffiti posted with my own twist. Once the MEK was on the ground OP in the spoon I mixed it with a toothpick held a lighter well below it and once it was semi dry I dumped it on a plate and went crazy on it with a razor. from time to time I scraped gunk off the razor and I put it aside. after chopping furiously I spread it out and nuked it for 10 seconds took it out razored it some more ten more seconds razored again 10 more seconds and then razor again. At this point I had a fairly uniform consistency that looked like regular OXY. I smelled it to make sure that I could no longer smell the MEK and I insufflated it. It lacks the familiar drip but the rush is there. I won't do it again until I thoroughly research MEK and it's possibility to harm, but I wasn't going to do this research without knowing it was a viable method. However, I do feel like I insufflated about 40 - 60 mgs oxycodone. Please note that I can tell it gelled a little bit but I can still breathe through that nostril.

Edit... The rush was shortlived and I blew a ton of gel from my nose but there was no discomfort whatsoever. I think that I was very conservative with the amount of MEK I added. I dont know if I will try it again I think I'd rather suck on them like a lozenge or grind them and swallow between bites of food.

 

[mr.muncheez]

I thought 160's got discontinued because of too many overdoses? I think thats what I heard, I could be wrong though.

Yeah, that's pretty much what I was getting at. They discontinued them as far as doctors writing scripts for them, I am not sure if a hospital can give them to a patient who is terminally ill..(ie Cancer pain). Now that they slowed these things down and made them near abuse-proof, maybe they will be able to start dispensing the 160's again?...who knows..

 

[HeaveHo94]

Yeah, that's pretty much what I was getting at. They discontinued them as far as doctors writing scripts for them, I am not sure if a hospital can give them to a patient who is terminally ill..(ie Cancer pain). Now that they slowed these things down and made them near abuse-proof, maybe they will be able to start dispensing the 160's again?...who knows..

thats what my mother was given for the last 2 months of her life. I remember checking them out, long and blue.

 

[HdoubleODeezy]

those old teva footballs look pretty good now don't they?
it's been a while since i have done OC's but does Teva still make the 80mg footballs? if so it would probably be easier to get those (and cheaper) and extract those instead of the new OP's which everyone is having trouble extracting.. i believe the Tevas imprints might have been 93/33? maybe? but like i said, their anti-abuse mechanism isn't as advanced as the OPs. I dont THINK.. i could be wrong. any thoughts?

 

[grafitti]

I tried the MEK method graffiti posted with my own twist. Once the MEK was on the ground OP in the spoon I mixed it with a toothpick held a lighter well below it and once it was semi dry I dumped it on a plate and went crazy on it with a razor. from time to time I scraped gunk off the razor and I put it aside. after chopping furiously I spread it out and nuked it for 10 seconds took it out razored it some more ten more seconds razored again 10 more seconds and then razor again. At this point I had a fairly uniform consistency that looked like regular OXY. I smelled it to make sure that I could no longer smell the MEK and I insufflated it. It lacks the familiar drip but the rush is there. I won't do it again until I thoroughly research MEK and it's possibility to harm, but I wasn't going to do this research without knowing it was a viable method. However, I do feel like I insufflated about 40 - 60 mgs oxycodone. Please note that I can tell it gelled a little bit but I can still breathe through that nostril.

Edit... The rush was shortlived and I blew a ton of gel from my nose but there was no discomfort whatsoever. I think that I was very conservative with the amount of MEK I added. I dont know if I will try it again I think I'd rather suck on them like a lozenge or grind them and swallow between bites of food.

i did it a little different with better results i left the pile on the plate , i used a op 80 , i soaked the pile , as 1 little piece makes life misreable i cannot believe how much one piece expands into goo , so i got the whole pile really wet and let dry for 1 hour mixing every 15 minutes getting it wetter made it lots better , m e k is probably not good for u ,i have short life expantcy so i do not care please research m e k and use to your own thoughts my last exp. with m e k , i will take them orally on schedule till i have a really badday then i will m e k it unless someone finds easier better method , i wish no one harm , just at wits end and hate what gov. did , they took away a pain reliever that worked so well and so fast and replaced it with one that is about half as good , we should be able to take them the way we want , it is the u.s.a. , soaking them thoroughly works better it eliminates the small pieces that make huge amounts of goo , i did think of one last thing perhaps refrigirating after soaking , who knows ? if u r young and healthy wheen yourself off them now would be my advice , life is short i am looking at 55 as the end , been on oxys for 10 years and time flew bye i missed alot , we are in this together someone will win hopefully not uncle sam , peace to all i gave it my best shot it works if u do everything perfectly and do not ingest even a little piece of that shit they call filler

 

[mr.muncheez]

Damn man...sorry to hear about your situation. Maybe you can talk to your doc and explain that the new formula just takes too long to work on the pain and you just can't sit around waiting 3-4 hours for pain relief. Maybe it's possible to lower your 80 count a little and add in breakthrough pain. My buddy is going through the same thing now. He had an anterior/posterior spinal fusion and has debilitating (sp) pain. He is on 120 80's a month and the old formula worked so well for him, now it sucks. This is the first month he had em, and he isn't happy with the change. He said he was going to ask his doc to take away 1 80 a day and add 4 20mg Roxi's to his regimine.

 

[Noddy Boy]

I personally have a friend that is prescribed OC 60mg, and he has recently received a script of the new ones.

He has always taken them orally and is complaining about withdrawl badly from the new pills.

After reviewing the link that shows all the details of the reformulation, it even states that a less of a percentage is released of the reformulated product.

I have a feeling that people are going to notice this, and the big dogs will have to re-formulate their product again to get a closer to match to the mechanism of how its TR works.

Its right here (OC Reformulation) on page 62, there is a line graph, check it out, they also show pics of what it looks like when you try to cook it up for IV administration.

 

[HdoubleODeezy]

^ it also only releases about 6.5mg/hr instead of the old ones releasing 10mg/hr
Because i guess the new ones are supposed to last 12hrs opposed to the old 8hr ones
so the same amount spread over a longer period makes for less of a release of the drug per hour combined with the fact that it doesn't release its oxycodone as efficiently as the old OC's i can see how people are going into w/d's from the new pills, they basically need to take 2 every 12 hours of OP's
opposed to 1 OC every 8hrs.

 

[Jabberwocky]

I hate to take this off topic, but would you consider this to be the reason why so many people are saying they don't work as well as the OC's? By "people" i'm referring to the people on here who have said they take it for legit reasons and taking it orally and untampered. It seems like this could be the cause because its the same dose but spread out 50% longer, so it would definitely seem weaker to someone who is used to a quicker release.

yeah definitely. they don't not work as well, it's just the release rate is lower and has been adjusted to be released over 12 hours compared to 8. a slight dose increase or having to adjust to the newer pills are options, along with upping the OP dose to fill the gap or possibly adding in an IR forumulation when breakthrough pain becomes a problem.

 

[Illadelphian420]

This may be a stupid idea but what about using acetic anhydride? Is there anyway you could use that to try and either break down the polymers or extract the oxycodone? Then maybe let that evaporate and be left with something snortable? Anyone care to tell me if that's a dumb/bad idea?

 

[sweetstufflover]

Acetic anhydride is not a common solvent, but a substance that's used to produce esters (for example).

 

[Illadelphian420]

Acetic anhydride is not a common solvent, but a substance that's used to produce esters (for example).

So does that mean it would be no good?

 

[DrTcInKC]

Absolute Futility.

Even with a colloidal solution of the desired opiate and the hydrated gelling substance (Hydroxypropyl cellulose or BHT im not sure which it is) , Drinking it still is less desirable at best to someone who is addicted to insufflation of opiates in general and much more importantly OC as the specific drug of choice. Bottom line? Either learn to like the PO route and accept its flawed nature, or return to the alternatives such as the M's, the green footballs, the R-215 Blues, roxi's etc etc etc.
It is oddly ironic that this move by purdue may infact have worldwide impact for addicts and their markets. . lol.

 

[c36bo]

these new op's suck ass. here in georgia they have takin over like kudzu!!! all these chemical extractions scare me cuz i cant afford to experiment. if u eat it in little pieces with coca cola and potato chips the salt and acidic nature of the 2 dont allow the pill to get back together in the stomach. 3 of my ppl have dun it and had success. I STILL NEED TO KNOW A SAFE WAY TO BREAK THEM DOWN FOR SNORTING. THX 4 ALL WHO MAY BE ABLE 2 HELP

 

[dancingtree]

re: mek toxicity

I read on this document http://des.nh.gov/organization/commissioner/pip/factsheets/ard/documents/ard-ehp-33.pdf
that MEK is highly water soluble.

I'm wondering if maybe after doing a thorough MEk treatment to your powder and allowing to dry and evaporate- and presumably after the ER polymer has been dissolved- maybe adding water to the dried residue, and allowing that to re-evaporate, will clean out any extra mek residue, since it dissolves with and I'm guessing evaporates with the water.