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The Big and Dandy 4-AcO-DMT thread - New incarnation

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what would peopl;e suggest for a first time on 4-aco-dmt, i am quite experienced with other psychadelics like lsd DMT srooms etc, i want to have a strong trip last time i took mushrooms i ate 7g of dried psilocybin srooms, would love to go back to that place......
 
I have tripped on this substance twice - both times at 30mg. This one feels quite benign to me, almost like a psychedelic sedative. You can probably go alot higher than 30mg. Though, I would reccomend testing the waters first with a smaller dose, to gauge your reaction to this chem - before embarking on a high dose quest.
 
if you're looking for a "7g shrooms" trip, probably around 40-50mg as most people seem to agree that 20-25mg of this material can be equivalent to 3.5g of mushrooms.

if you've never tried anahuasca / oral dmt / psilohuasca, i highly recommend it. nothing quite comes close to the huasca in terms of complete obliteration of the mind.

3g peganum harmala seeds followed by 30mg 4-aco-dmt in 30 minutes ought to do the trick.
 
yeh iv had aya before but i used too much syrian rue ( not knowing it was this that caused the nausea) and made everyone ill, MAD trip though.....
another wuick question, is there a way to test that what i got in the post is actually 4-aco-dmt, i have marquis reagent if anyone knows a reaction to that? or any other tests i can do
 
Does anyone know a good solvent for 4-aco-dmt? I'm getting a gram and want to make 20mg doses. Capsules are fiddly and very time consuming, so I was thinking make a concentrated solution, and drop it onto sugar cubes. But I'm in the UK and we can't get everclear. So I was wondering if anyone knows whether isopropyl alcohol or acetone will dissolve 4-aco.

yes it will disolve in acetone or isopropyl alcohol.
But 4 aco dmt does not keep well in solution.

i dont recomend you do this.
 
I still need to experience other psychedelics to give a more diverse opinion, but I have to say, this stuff is amazing. Had my soul cleansed thoroughly last night with a ~30-40mg oral dose. I was originally going to dose outside, my impatience made me dose last night inside, but this turned out to be a very good thing, I would probably be seriously hurt or at the very least very dirty, covered in insect bites and pretty cut up now if I had tripped outside with this dosage.

Trip report: http://www.bluelight.ru/vb/showthread.php?t=506406

So yeah, just to warn people, this has a very steep dosage curve. I took ~20-30mg my last trip and it wasn't even 1/100th of the intensity of this. If you're not looking for an intense ride, remember to always weigh/measure out your doses, and go up in very small increments. I however did want an intense experience, got more than I bargained for, it was very scary and unfriendly at some points and yet at the same time even this fear was utter bliss. I found nirvana, and I was reborn.

Also seems like dosage has a big effect on duration. ~10-15mg lasted 4-6 hours, ~20-30mg lasted 7-9 hours, and ~30-40mg has been going for almost 16 hours, still not entirely at baseline.
 
Thats interesting. 30mg of the fumarate felt like a light/medium trip to me. Duration around 4-5 hours at the most. I seem to have a bit of a tolerance to this one, though. Next time I will try 40-50mg.
 
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what's the difference in appearance between the fumarate and the ****(hydrochloride?what?)???

Is the fumarate more matte and slightly SLIGHTLY beigey-white??

AFAIK the fumarate is the most common...I'm assuming it's the one I had - which was beigey white, and matte.
 
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I'm looking forward to trying this substance! I do have a question though. I'm pretty sensitive to mushrooms, like 1-1.5g to me is like 3.5-4 to another person of the same batch. What would the dosage be like for me? I don't want to take like 15mg and be in like a 6g mushroom trip. <3
 
what's the difference in appearance between the fumarate and the ****(hydrochloride?what?)???

Is the fumarate more matte and slightly SLIGHTLY beigey-white??

AFAIK the fumarate is the most common...I'm assuming it's the one I had - which was beigey white, and matte.

Slightly beigey-white and matte would be a perfect description of my 4-AcO fumarate.
 
Does this substance bcome more or less sedating teh higher the dose people??

Thanks man ^ ---- what other salts does this come in then?? on teh market at least

I'm looking forward to trying this substance! I do have a question though. I'm pretty sensitive to mushrooms, like 1-1.5g to me is like 3.5-4 to another person of the same batch. What would the dosage be like for me? I don't want to take like 15mg and be in like a 6g mushroom trip. <3

I would think frm MY reactions to psychedelics (i'm quite sensitive), from my 14mg experience it was like taking 1.-1.5g mushrooms...more towards the gram though...quite mild, and sedating...

Does this substance become more or less sedating, the higher the dose people??? Putting that question out to all of ya.

Getting some more of this chem in about a week and want to hit up a 30-40mg dose, see where that takes my mind and body.
 
Is 4-ACO-DMT similar to 5-MEO-DMT but it lasts far longer???

I've never done 5-MeO-DMT but I can safely say they are far from similar. 5-MeO-DMT is a short intense trip, more what you would expect from DMT, whereas 4-AcO-DMT is often referred to as a smoother mushroom trip. Obviously this is a crude sketch of both but I'm just trying to point out they are very different.
 
Does anybody know who discovered 4-ACO-DMT and when they discovered it; or at least a rough estimation of a time at which this substance was first noticed? It seems like it just popped out of nowhere from nobody haha. This chemical and 4-HO-DMT among the next chemicals on my list to try.

I've gone to 22mg with 2C-E and I've taken up to an eighth of dry mushrooms, also I have pretty extensive experience with LSD. I've also had a threshold DMT experience which has had me anticipating to have a breakthrough DMT experience.

Based on the research I've done on this chemical, it seems appealing to me as I am a fan of the more classic psychedelics. Any info on it such as it's origin and time thereof would be greatly appreciated. Thanks!


Edit: lol I found this on Erowid :

"History #
4-Acetoxy-DMT is a novel compound with relatively little availability on the research chemicals market. As of 2007, its use appears to primarily be confined to psychedelic connoisseurs."
 
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i recall seeing a paper by Nichols on synthesis of psilocybin (4-PO-DMT) and his note that it is very difficult to synthesize in good yield due to its hydrolyzation to psilocin (4-HO-DMT) and subsequent oxidation during work-up. he then says that 4-AcO-DMT can be used in clinical trials as a replacement for 4-HO and 4-PO-DMT because it is pharmacologically similar and much much easier to synthesize with good yield and purity
 
Does anybody know who discovered 4-ACO-DMT and when they discovered it; or at least a rough estimation of a time at which this substance was first noticed? It seems like it just popped out of nowhere from nobody haha. This chemical and 4-HO-DMT among the next chemicals on my list to try.

I've gone to 22mg with 2C-E and I've taken up to an eighth of dry mushrooms, also I have pretty extensive experience with LSD. I've also had a threshold DMT experience which has had me anticipating to have a breakthrough DMT experience.

Based on the research I've done on this chemical, it seems appealing to me as I am a fan of the more classic psychedelics. Any info on it such as it's origin and time thereof would be greatly appreciated. Thanks!


Edit: lol I found this on Erowid :

"History #
4-Acetoxy-DMT is a novel compound with relatively little availability on the research chemicals market. As of 2007, its use appears to primarily be confined to psychedelic connoisseurs."

In the 4-HO-DMT entry in TiHKAL both the phosphate (psilocybin) and acetate (psilacetin, 4-Aco-DMT) are mentioned.

i recall seeing a paper by Nichols on synthesis of psilocybin (4-PO-DMT) and his note that it is very difficult to synthesize in good yield due to its hydrolyzation to psilocin (4-HO-DMT) and subsequent oxidation during work-up. he then says that 4-AcO-DMT can be used in clinical trials as a replacement for 4-HO and 4-PO-DMT because it is pharmacologically similar and much much easier to synthesize with good yield and purity

those synth problems are also mentioned in the TiHKAL entry linked above. Could you link that Nichols article? I'd like to check that out.
 
Does anybody know who discovered 4-ACO-DMT and when they discovered it; or at least a rough estimation of a time at which this substance was first noticed? It seems like it just popped out of nowhere from nobody haha. This chemical and 4-HO-DMT among the next chemicals on my list to try.

i dont know who invented it, but the original custom synth was ordered by a BLer in 2006.
I dont think he thought it up though, as changing an ester isnt exactly difficult to think of (hydroxy to acetoxy).
But its thanks to him we all get to enjoy it now
=D
 
Found that nichols article... it was on erowid... duh...

And I'm unaware of it being mentioned anywhere before TiHKAL, so I'm going to just assume Dr. Shulgin was the first to synthesize & test it. You'd think Hoffman & Co. at Sandoz would've done that in the 50s or 60s, but if they did I can't find any record of it. Go figure
 
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