ANTI-depressant/anxiety pill that works?? (Think outside the box)

Colmes

Bluelighter
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Mar 27, 2008
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889
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new jersey
Ever since my relationship ended with my ex fiancee - which coincidentally was at the same time that I switched Colleges - from a 2 year, to a pretty darn good 4 year college, my anxiety has gotten worse. I dont know anyone like I did at my old school, and the workload is at least 3-4 times more.

I've always had some sorta anxiety, and it just magicalllly disappears when I get home (my comfort zone I guess) - I'm fine going out anywhere, just not school - i get all nervous, and I cant concentrate - this is a big problem as school is important...

I've tried Paxil - Wellbutrin(only gave it about a week as I couldn't have sex), Prozac (current med that ended brain zaps from paxil), Brief trials (1 month) of Pristiq, and finally, a tricyclic, Nortriptyline. I'm on prozac - none of this shit works. Also - i'm on 20mg valium a day, used to be on 4mg clonazapam a day, also was on 4mg xanax a day at one point, basically my point - benzos are out of the question - my tolerance is monstrous, so they dont really reduce my anxiety, I just need them.

I self medicated with opiates (i'm so unique, I know) but I have no supply of 'real' opiates (im prescribed tramadol because I got myself addicted to subutex real bad after a brief oxycodone habit. Yeah...opiates do their job...until you need them just to not feel sick, and really, its not an option. That is, its not a logical option.

What else have I been prescribed? Adderall, vyvanse, focalin - I abused each and every one. Man, that stuff made me so out-going, made me driven, but eventually, my tolerance got really high, I didnt sleep as much as I should have, didnt eat like I should have, and was probably hurting my heart. Plus the comedowns were unbearable. So what, it isnt meth or crack...anyone who knows what a comedown after a ritalin or adderall binge is like - repeatedly, knows it sucks.

Ok so I got off that with some after depression, tiredness for a month or so. I then was prescribed Provigil.

Provigil is an interesting drug. Weird thing, if I take it at...9PM, at home, or before im about to go out to anywhere (except school) I get a major moodlift - well...not "major" but its energizing. However, if I take that SAME dose at ...say...11AM at school - I will just have anxiety, faster heart rate, you know, nervous energy. Its like clockwork.

As you can see my doctor and I have tried a good amount of medications to combat the anxiety (depression is more minor - its the anxiety that really gets me) Tramadol was great for awhile but now its just another pill i gotta take.

I know i'm naturally an introvert. I just want a girl - i dont care for parties, showing off, or any of that shit. But when I was on vyvanse (my mood changes going from VERY up to VERY down was what drove my ex fiancee away (mainly, shes still a heart puller outer stomper).

Bupe was interesting as an anti-depressant, but I know what its like w/d off it when you have been on it for awhile, and its a very strong drug. Plus its potency as an anti anxiety drug diminishes, as do most pharms.

So my question, outside the box thinking. I KNOW there are people out there that have been through this shit. Ive never tried medications like librium, or lithium, ya know - drugs for Manic behavior or bipolar. I also have never tried any antipsychotics - like, well, i dont have to name them. MAOis scare me, and I wont take them. Look, right now I just took (30min ago) 20mg of ambien, i m not tired, and im on aim actually being social - but it isnt practical, it will be the next diazapam, clonazapam, or tramadol. Something that worked at first, then, stopped, but is needed to be continued as it is addictive. I think my doctor has kinda ran out of ideas too - other than just cycling different SSRIs, which i've kinda lost hope in. SNRIs, yadda yadda.


If ANYONE has had an anxiety problem - one that is more than normal anxiety - and interferes with their life - it prevents me from talking how I want, and just being me. the breakup was Deeevvvestating for me, I mean, all are, but we continued it off and on for another 4 months or so after we broke up - really fucking up my healing process.

Any opinions are greatly appreciated.
 
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Can a mod move this to TDS please? I think it may get more responses there, if you agree, move it ;)
 
I would say the best thing you can do it just get off of all the meds (you said urself they dont work) and start going out and doing more shit with friends and people and stop looking for the answer in a pill because in my opinion it doesnt exist.

Ive tried like 50 psych meds for depression and anxiety and they dont work long term---

If your too nervous to even go out you could take opiates JUST INITIALLY to allow yourself to get confident and comfortable with the activity and then stop.

This is just my 2 cents and from my experience that magic pill doesnt exist.
 
I would say the best thing you can do it just get off of all the meds (you said urself they dont work) and start going out and doing more shit with friends and people and stop looking for the answer in a pill because in my opinion it doesnt exist.

Ive tried like 50 psych meds for depression and anxiety and they dont work long term---

If your too nervous to even go out you could take opiates JUST INITIALLY to allow yourself to get confident and comfortable with the activity and then stop.

This is just my 2 cents and from my experience that magic pill doesnt exist.

yea i know...

essentially you're right, but I have so much schoolwork - Im barely getting by as it is, if I throw an attempted benzo taper on top of this...it just isnt the right time
 
Wait, so let me get this straight... you're looking for an anxiolytic, mood-boosting drug that is practical to take on a daily basis? Unfortunately, in the US there aren't many (if any) decent pharmaceuticals available for this. Antipsychotics (like amisulpride) may be potentially useful if taken at low doses, however their side-effects are unacceptable. Buspirone (Buspar), a 5-HT1A receptor partial agonist could be beneficial in doses above max FDA recommendations, but it also acts as a D2 antagonist, severely reducing dopaminergic neurotransmission at that receptor. Bupropion (Wellbutrin) would have potential as a mood-lifting antidepressant, but it's much more selective to norepinephrine than dopamine to possess any significant efficacy for most patients. The nonselective MAOIs work fantastically (I had excellent results with Nardil), but many would find the dietary restrictions too much of a hassle to follow, and sometimes a food interaction may not even be explainable so even following the diet may not prevent hyperadrenergic events.

The truly effective medications are the ones that have been pulled off the market or are only available overseas. Tianeptine (Stablon) is a Selective Serotonin Reuptake Enhancer (SSRE) which has proven efficacy as an anxiolytic and mood-brightening rather than mood-blunting antidepressant. Tandospirone (Sediel) is like China and Japan's version of buspirone, but it is much more selective for the 5-HT1A receptor making it an incredible anxiolytic (with efficacy comparable to benzodiazepines) and antidepressant at twice the recommended dose. The dopamine reuptake inhibitor amineptine (Survector) is reportedly one of the strongest mood-booster/motivation enhancers out of anything currently on the market, but unfortunately it was withdrawn from the market due to concerns of abuse potential. All three of these are available online, though are very expensive.
 
all the psych drugs i've tried have basically fucked up my life for a decent period of time during and after use. not worth the headache and i ended up with even more mental problems than before

the only thing that has really helped me is eating well and taking supplements like amino acids and high-dose vitamins... B6 and B12, omega 3 fatty acids.. those help a good amount with mood, but the change isn't instant so a lot of people give up before they've started. meditation and moderate exercise are good for a lot of people... i find they relax me and help me focus better

atm my bipolar is pretty bad and i'm thinking of ordering a natural supplement of L-DOPA to boost my dopamine levels. i don't know if it's a placebo or not but at this point i'm willing to try it as i can't tolerate how things are right now

i'd say some pharms are a good short-term fix for severe problems, but long-term they only lead to more problems

best of luck,

G
 
Are you seeing a therapist as well as your doctor? People who are in therapy while they are on medication see much better results than people who are just taking the medication alone.

Also, even if you have side-effects when you start a drug, keep with it for a while (unless the side-effects are a serious threat to your health) as many side-effects will fade away the longer you are on a medication. Don't get frustrated if everything doesn't get better immediately, keep with it.

As a person who has struggled with anxiety and depression myself, I feel for you and I wish you the best of luck.
 
do not take seraquel for anxiety unless you want the equivalent of a lobotomy. Just my opinion there.
 
Thank you all for your replies. Ill try to answer some of the Q's

I know there is no magic pill - but its life. I'm not the first person to look for some help. There will always be backstabbing scummy people, and shitty situations, its my ability to handle them that concerns me.

cognitive behavioral therapy...not really....sort of. The doctor is a psycho-pharmacologist. So he hears me out - but no, its not therapy.

I haven't heard great things about mood elevators only available in china - something I don't really want to get into.

The only thing that let me be myself was Vyvanse (amphetamine - prescribed) but I have an addictive personality, and as I said, the comedowns became real bad. But it helped me through school...and forming some relationships... Maybe I needed a lower dose and some more self control. I dont know if I could even get it prescribed to me anymore.

It just fucking sucks. As far as I know we get one life - and I spend half my fuckin mind power thinking about illogical shit - and measuring my own self worth through how other people view me. Its stupid, but hey, i'm human. But frankly im sick of it. I'm going to be 24 in less than a month, I want to enjoy life more than I am. Im not looking for magic in a pill, that makes the most devastating events seem euphoric - i'm looking for stability.

Anti-psychotics, brain damage, bleh, what doesnt cause brain damage? So does anxiety - take a look at SPECT scans of a normal brain and a brain that is riddled with anxiety. Take a look at the brain of someone who smokes 2 packs of cigs a day and drinks a lot of coffee. What can I say.

Thanks for the good vibes~ I dont know what to do...I guess i'll try to make an appointment with my doctor who is always too busy.

I cant drop any classes - take my word for it =x
 
Seroquel


Eminem mentions it on his album "I just picked my prescription for seroquel up, would you like to share a pill or two with me?" Maybe i'll take his advice, lol.

What affects do medications like lithium, librium and others have on anxiety ?(and what are similar type medications? Geodon, topomax ect? are they pretty much just for bi-polar disorders?(which I do not have)


But ugh, lithium...you gotta get your blood levels checked n shit - i'm not up for such a serious prescription. I dont know what I want, after all, i'm not a doctor.
 
If the physical symptoms of your anxiety disapear,
maybe you would find it easier to feel less anxious mentally as well.

Betablockers effectively get rid of the physical symptoms of fear by reducing the body's response to adrenalin.
If you ever decide to get off the benzo's all together (tapering very slowly as the ashtod method prescribes!!)
betablockers can help you to take the edge of withdrawal symptoms as well.


Betablockers have side-effects (allthough new generation like nebivolol don't have many side-effects),
and many people can take them without serious side-effects so maybe you'd benefit on them.

The people who can't tolerate them usually can't because of poor blood circulation, low heartrate, low bloodpressure or erectile dysfunction...
but if you take them for adrenalin then possibly a really low dose would suffice,
and the chance you'd have a problem with symptoms at a low dose is rather low.
 
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If the physical symptoms of your anxiety disapear,
maybe you would find it easier to feel less anxious mentally as well.

Betablockers effectively get rid of the physical symptoms of fear by reducing the body's response to adrenalin.
If you ever decide to get off the benzo's all together (tapering very slowly as the ashtod method prescribes!!)
betablockers can help you to take the edge of withdrawal symptoms as well.


Betablockers have side-effects (allthough new generation like nebivolol don't have many side-effects),
and many people can take them without serious side-effects so maybe you'd benefit on them.

The people who can't tolerate them usually can't because of poor blood circulation, low heartrate, low bloodpressure or erectile dysfunction...
but if you take them for adrenalin then possibly a really low dose would suffice,
and the chance you'd have a problem with symptoms at a low dose is rather low.

Hmm educate me a little more about this?
Are you referring to a medication like Clonidine?

Could the benzos i've been taking for the past 3 years [primarily clonazapam] 4mg-6mg/day be actually contributing/exacerbating my anxiety and or depression? Do i need to go to inpatient to get off? i mean im seriously on benzos...not a "3 times a week deal" or can I taper without terrible pain? I mean I know a SLOW taper, but when the medicine is ceased would I have terrible anxiety? I notice its began to effect my memory. I cant take tests for shit anymore.
 
Hmm educate me a little more about this?
Are you referring to a medication like Clonidine?

Could the benzos i've been taking for the past 3 years [primarily clonazapam] 4mg-6mg/day be actually contributing/exacerbating my anxiety and or depression? Do i need to go to inpatient to get off? i mean im seriously on benzos...not a "3 times a week deal" or can I taper without terrible pain? I mean I know a SLOW taper, but when the medicine is ceased would I have terrible anxiety? I notice its began to effect my memory. I cant take tests for shit anymore.

Of course they can! I guarantee it! I took xanax on and off for over a year, then quit (didn't need to taper cause i wasn't taking it daily, but even a few times a week would produce hellish symptoms).

Get off the benzos, read up here, especially the ashton manual. Register and get on the forums.

http://www.benzoisland.org/benzoforum/forumdisplay.php?f=36

It'll show you how to taper and get your life back on track. Get off all other drugs. It'll suck for a while but it gets better. I'm 92 days clean off xanax, and although I feel good, I STILL have problems. If that tells you anything! Good luck man.

Also, if you keep looking for more drugs, I guaranfuckintee your problems will get worse.
 
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