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2c-b fly and the future of research chemicals

Danguba said:
Yes, all our consciousnesses are so expanded that they're bursting all over the place.

Yet I have yet to see a single 'discovery', from hundreds of trip reports & other 'research' which isn't just reiteration of pantheism or some vague thing resembling musings of a Ionian philosopher (say Anaximander) from cca. 600BC.

I don't think an 'expanded consciousness' should be defined as the ability to create novel philosophical concepts, but rather the complete understanding, through experience, of ageless concepts.
 
dimensiontripping said:
well, IMO THC derivatives (and what about the LSD ones) are really overlooked too. CP55490 etc...i think should be a bigger deal. maybe it is smoking the weed that makes it fun and a good time to socialize. "lets smoke a blunt" instead of lets all eat this synthetic thc analogue drug on paper!

I totally understand this analogy, but to me. It wouldn't matter, id love eating some synthetic thc. I'll try anything once.

dimensiontripping said:
Are there active chemists who are actually involved in developing new phenethylamines, tryptamines and the like? I mean the psychoactive list is already in the hundreds, but it seems we may only be at the beginning of modern drugs.

There has to be active chemists developing new RC's or we wouldn't have the ones we have now. Shulgin isn't capable of creating every SINGLE one, but he sure as hell started the basis of all that is to come. :) %) %) %) %)
 
I think there will be a lot more substituted piperidines, though I am not sure if they really count as psychedelics.
 
4-ho-met

feelgoodhit said:
oooh, what an exciting topic!

i remember at some point recently there was a thread involving an entirely new psychedelic, but it somehow got lost in the storm. i'd love to see that again while NOT ++ tripping on 2C-T-21


I think it was 4-ho-met.
 
I want to see N-substituted AMTs

I know 5-MeO-AMT has seen the light of day, but there are so many others...
Think about every tryptamine that you've tried before, seen in TiHKAL, or Erowid. Imagine N-subbed 4- and 5-MeO's HO's and AcO's as well.
AMDMT anyone? (feelgoodhit: potentially wildly visual!)

-----------------------------
The next compounds for my interest are substituted phentermines. 3,4 MDO-phentermine (MDA and MDMA-like compounds) and then the 2C family, and 2C-x-Fly compounds.

It seems to me that they should be logical extensions of whats already out there.
Anyone else want to chime in?
 
oh man AMDMT, i cant imagine...and N-sub AMTs sounds very interesting too...maybe since some of these would be building directly off a widely scheduled compounds, they're going to continue to extend off the extensions? (i.e. 2c-e-FLY, etc) Also, you think as we add on to analogues they'll become less of analogues and more legal?
 
I'd love to think so. Wish I knew where to find some of the current "glut" of analogues.

What about 4- or 5-nitro-tryptamines?
4- and 5 amine subbed T's?

I'm a chemist so I could go on and on, but you get the idea. The theory is already there, just need someone to make it.
 
oh man AMDMT, i cant imagine...
The compound you speak of it a,N,N-Trimethyltryptamine.

a,N-DMT was terrible so I doubt this is going anywhere interesting. A few people have sampled it and said it wasn't all that amazing: http://www.bluelight.ru/vb/showthread.php?t=388943

What about 4- or 5-nitro-tryptamines?
Probably too polar

4- and 5 amine subbed T's?
...Would you really want to ingest anilines? You're asking for liver damage.

The next compounds for my interest are substituted phentermines. 3,4 MDO-phentermine (MDA and MDMA-like compounds) and then the 2C family, and 2C-x-Fly compounds.
The methylenedioxy compounds are already controlled as position isomers.

Now, alpha,alpha-dimethyltryptamine might be interesting if it weren't a positional isomer of alpha-ethyltryptamine...
 
N-substituted AMT-analogues are well known in Tihkal already, and none of them were interesting as I recall. Also methylenedioxy-phentermine, MDPH, is already in Pihkal, and it seems that it doesn't do much by itself, but works as a "primer" that synergizes with the effects of hallucinogens.

What I would like to see would be compounds such as phenmetrazine and fencamfamine with a methylenedioxy-ring.

But, about phentermine analogues... I had an idea the other day: substitute the phenyl in PCE with a benzyl, and voila you have a phentermine analogue - phentermine with n-ethyl group and both a-methyl-groups extended into a cyclohexane ring. How about it, a stimulant with very probably NMDA activity?

bce.png



Oh, a footnote: of all the possible flies and dragonflies I would most like to see & sample 2C-TFM-DFLY. Good potency via the TFM group and fully aromatic wings, not a terribly long duration due to the 2 carbon tail. And plain 2C-TFM sounds interesting as it is, so...
 
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xorky said:
I found 2C-B-fly to be wonderful.

Off-topic:
In what ways did you find it to differ from 2c-b?
Some of the available trip reports claim it to be very similar except in terms of duration. . .
 
2c-EA-fly
(ethylamine)

its the same fowards as it is backwards! probably the most aesthetic, but potency is probably shit lol. id eat it.

NBOH-G-12

(3-methyl-4-ethyl)
 
NBOH-G-12 would probably not be very potent, since phens with the hydroxy/methoxybenzyl at the amine do not seem to work so well with alkyl substitutions in the 4-position... in fact they only seem to work well with halogens in the 4-position.

But how about 2C-G-2? Or better yet, if you want symmetry... TCB-2C-G2!

tcb2cg2.png


^ TCB-2C-G-2 (what a monster name)
 
...Would you really want to ingest anilines? You're asking for liver damage.

Check the image... Its not much of an aniline anymore. LSD has a 3rd amino group. (Albeit not attached to the aryl system)

In the body's Oxidative breakdown system, its going to be treated like a tryptamine, because thats which enzymes it going to fit best. Its increased polarity will more likely do kidney damage, as they are the treatment system for polar compounds.

@Dread... Those two strained 4C rings could cause toxicity issues, especially due to the potential reactivity of being one position removed from an aryl system. It could metabolize to at least eight different compounds just based on those rings breaking.
 

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I'd love to see permutations of the flys dragonflys and hemi-flies become available. Perhaps Aleph-dragonfly? I have a feeling chloro-dragonfly would be a winner, as would methyl, ethyl, and trifluoromethyl. Also, the 3,4,5 equivalents of the dragonflys? Just switching around an oxygen really...
 
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