I strongly disagree that 7-OH is the best type of opioid next to fentanyl.
7-OH has it's place indeed in the opiate/opioid field but it is not a drug that can be used daily for chronic pain, chronic pain syndrome, cancer pain, post-op acute pain, and breakthrough pain needs.
Opioids like Oxycodone, Diluadid, Morphine, Methadone, Fentanyl, Suboxone, and Oxymorphone will work for decades for daily long-term treatment without having to increase dosages on a regular basis. 7-OH is the exact opposite.
I am sure many people will disagree with me on this and that is fine with me. My point of view is based on being physically dependent and addicted to Rx opiates/opioids for going on 40 years. I haven't had to increase my Roxicodone 210mg and Methadone 40mg in 13 months & I am doing just fine.
The only way I can get a desired result from Opia 7-OH is to take 480mg in one dosage.