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🌟🌟 Social 🌟🌟 PD Social Thread 2022-2025 v. Year of the Phenethylamine

I suppose since I've mentioned the Holy Modal Rounders again I better continue my tradition of ending my long meandering walls of text with Rounder songs. Since they're the 2nd greatest band of all time and have never had more than 500 fans at any one time. They are the definition of a cult band.
I had a friend who loved them. She took me to see Peter Stampfel at the Satellite Lounge in 1994 in NYC. A little blurry. Maybe it was the Holy Model Rounders but for sure Peter Stampfel. Did a good version of Euphoria.
 
It's taken me some months since I backtracked on my withdraw of topical corticosteroids, but my skin has finally calmed down enough that I've been able to resume most of my normal activities. It still looks pretty crappy and is quite itchy most of the time, but it's still way way easier than it was. I also have a strict sun budget because I'm very photosensitive, but I'm hopeful that the process of gradually hardening against the sun is helping to regulate my skin and accelerate the healing. I'm also very happy that I can reasonably tolerate something like 2-3 hours per day outside now.

This also means I'm starting to take psychedelics again. I'm mostly nibbling right now, but I anticipate I'll take a full trip pretty soon. I actually ate some mushrooms yesterday for the first time in over a decade. It was a bit exciting because they were of unknown potency. The last time I'd had mushrooms, I'd eaten a tiny amount of some gnarly looking aborted shrooms, and they gave me an unexpectedly powerful trip. I'd made a rule for myself to not take mushrooms unless they were blended to a well-mixed powder, which I could then titrate from a low amount. However, circumstances arose in which I had some 3.3 g of fresh P.cubensis of unknown potency in my hands. I didn't want to go through the trouble of drying them, but I didn't want them to go to waste either. I felt like the mushrooms willed me to eat them, so my wife and I split them. The trips were mild---like a +.5, but enough to give the rest of the day a bit of sparkle and a nice glow on the day after.

I think I will be eating more shrooms in my future, in addition to all my other favorites. Even though I enjoy long trips, shorter trips are more convenient, and unfortunately my favorite short-acting phenethylamines won't last forever. Mushrooms on the other hand can be easily replenished. I look forward to further reacquainting myself with these old allies.
 
I do think there should be laws severely limiting and restricting this practice though.

This I strongly agree with. It even feels to me like drug testing employees goes against human rights. Stigmatizing people for arbitrary reasons.

@Esperighanto we were at a pump track, mixed dirt and asphalt - asphalt on the berms and dirt in between. He dropped straight in on one of the berms (something he's done many times) and I think he must have tweaked his handlebars and he just went over, hitting his head on the bar on the way and then headfirst into the asphalt. Thank god we had him in a full face helmet. It was pretty scary because he was moaning but completely unconscious, eyes open but no one home. At first I couldn't tell if he had a spinal injury, so it was such a relief when he started moving his legs. It took him a few minutes to regain consciousness, and then 10 more before he started forming memories again. He's pretty young and wasn't super advanced at BMX, just doing racing not really tricks or anything. In the end he had a bad concussion but no spinal injury or brain bleed so we felt lucky
Ouch that's scary!! Glad your kid is ok !
 
I've been having severe sleep issues lately, and I don't really know why. When I say lately, I actually mean for months on end. I've been making it an effort to go to bed early to try and get a decent amount of sleep, but then I wake up for no apparent reason at like 4:30 am and can't go back to sleep for the life of me. I was using melatonin to some success for a couple of months, and it kinda worked for a while ..? Then I got scared my pineal gland would shrink and lose it's ability to biosynthetize melatonin if I took it chronically, kind of like when people take steroids for too long and their balls get smaller and atrophied, and I don't even know if it's a valid concern, like I got conflicting information about it when I tried looking into it, the most current reviews just say there's not enough data on chronic administration, and although existing data doesn't show adverse effects after long-term use I got paranoid anyway. So I switched to CBD and I also think it was working just fine but I don't know if it's just tolerance developing but for the last couple of weeks it hasn't been doing shit and it's back to insomnia. I didn't get more than 5 hours of sleep any night this week and this friday morning getting out of bed felt like an impossible task.

Anyone has any reccomendation? I'd rather not take benzos or other GABAergics, but after many sleepless nights in a row I just do that, although the sleep doesn't feel as "refreshing" to me when I do (could also just be the accumulated tiredness). I think maybe exercising in the evening could help me get physically tired and sleep deeper (I think the main problem is that I've always been a light sleeper), but is hard getting the time and energy specially when I feel tired all the time from not sleeping well.

It's a real nightmare.
 
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I've been having severe sleep issues lately, and I don't really know why. When I say lately, I actually mean for months on end. I've been making it an effort to go to bed early to try and get a decent amount of sleep, but then I wake up for no apparent reason at like 4:30 am and can't go back to sleep for the life of me. I was using melatonin to some success for a couple of months, and it kinda worked for a while ..? Then I got scared my pineal gland would shrink and lose it's ability to biosynthetize melatonin if I took it chronically, kind of like when people take steroids for too long and their balls get smaller and atrophied, and I don't even know if it's a valid concern, like I got conflicting information about it when I tried looking into it, the most current reviews just say there's not enough data on chronic administration, and although existing data doesn't show adverse effects after long-term use I got paranoid anyway. So I switched to CBD and I also think it was working just fine but I don't know if it's just tolerance developing but for the last couple of weeks it hasn't been doing shit and it's back to insomnia. I didn't get more than 5 hours of sleep any night this week and this friday morning getting out of bed felt like an impossible task.

Anyone has any reccomendation? I'd rather not take benzos or other GABAergics, but after many sleepless nights in a row I just do that, although the sleep doesn't feel as "refreshing" to me when I do (could also just be the accumulated tiredness). I think maybe exercising in the evening could help me get physically tired and sleep deeper (I think the main problem is that I've always been a light sleeper), but is hard getting the time and energy specially when I feel tired all the time from not sleeping well.

It's a real nightmare.
That sucks.. and when it becomes a focus it gets worse.. Maybe try trazodone or a first generation antihistamine? If those don‘t help a few milligrams of zolpidem will probably do the trick but I understand that you don‘t want to use it chronically. Some newer options would be the orexin antagonists (eg. lemborexant, suvorexant) but depending on where you live these might be unavailable or unaffordable, the reports sound quite good though.
 
@Img_9999 I struggled a lot with insomnia as a kid and eventually gave up on caring about it and that helped a lot. I realized that some people just need less sleep. Looking back I did have a lot of stress that was keeping me up, but just accepting the fact that I wasn't going to sleep 7h or whatever expectation helped me a lot and paradoxically I ended up sleeping more. So now if I can't sleep I usually just get up and read a book. I do take low doses of melatonin here and there if I have a couple of bad nights and it helps a lot but I agree it doesn't seem like a good habit to take it every night.

Other things that help for me is no coffee after 1pm, no screens before bed, lots of exercise during the day. But the main thing that helped me is looking at sleepless hours as bonus time that I get to read while all of those suckers in the world are unconscious.

Maybe there's a shred in there that's helpful for you, maybe not. Everything's different for everyone.
 
I've been having severe sleep issues lately, and I don't really know why. When I say lately, I actually mean for months on end. I've been making it an effort to go to bed early to try and get a decent amount of sleep, but then I wake up for no apparent reason at like 4:30 am and can't go back to sleep for the life of me. I was using melatonin to some success for a couple of months, and it kinda worked for a while ..? Then I got scared my pineal gland would shrink and lose it's ability to biosynthetize melatonin if I took it chronically, kind of like when people take steroids for too long and their balls get smaller and atrophied, and I don't even know if it's a valid concern, like I got conflicting information about it when I tried looking into it, the most current reviews just say there's not enough data on chronic administration, and although existing data doesn't show adverse effects after long-term use I got paranoid anyway. So I switched to CBD and I also think it was working just fine but I don't know if it's just tolerance developing but for the last couple of weeks it hasn't been doing shit and it's back to insomnia. I didn't get more than 5 hours of sleep any night this week and this friday morning getting out of bed felt like an impossible task.

Anyone has any reccomendation? I'd rather not take benzos or other GABAergics, but after many sleepless nights in a row I just do that, although the sleep doesn't feel as "refreshing" to me when I do (could also just be the accumulated tiredness). I think maybe exercising in the evening could help me get physically tired and sleep deeper (I think the main problem is that I've always been a light sleeper), but is hard getting the time and energy specially when I feel tired all the time from not sleeping well.

It's a real nightmare.

I relate to this 100%. I actually was fired from my last job due to sleep issues. I just wouldn't be able to get to sleep and stay asleep which led to me ALWAYS being tired and groggy. What led to my firing was the fact that I'd end up so exhausted that when I did finally manage sleep, I'd end up sleeping through my alarms. After multiple occurrences of this they canned me. I can't do benzos for sleep due to addiction to them in the past. Not out of concern of becoming addicted to them again (they now hold zero appeal and I can use them as a tool now), I just become addicted very quickly due to the kindling effect. If I had to use them 2 days in a row I can almost guarantee I'd experience some sort of withdrawal or bad rebound. Zolpidem never helped my sleep whatsoever. Zopiclone is probably the sleep med that has proven the most effective for me. It is still something you dont want to become dependent on, but it's very effective for getting to sleep and it never made me feel groggy in the morning. I also found it to have low abuse potential compared to Zolpidem or benzos.

I haven't tried them but I have heard good things about Amanita Muscaria. I'd avoid the gas station gummies but there should still be some clearnet vendors.

The thing that has been helping me has been Mirtazapine. I take between 7.5mg-15mg every night. As it kicks in you begin to feel very groggy, to the point that you're basically gently urged to go to bed. When I have to wake up early for work, I'll take it at like 7 or 8pm. I have always been a night owl, I hate even attempting to go to bed before midnight, and without medication I typically naturally fall asleep around 4-6am. I have no problem going to bed early with Mirtazapine in my system. Part of me still wants to fight it and stay up late, but the grogginess is hard to fight and it also is beneficial for anxiety, which I suspect is the core reason I like staying up. Anxiety about the following day so I stay up late to avoid it. Initially there was some morning grogginess but nothing too bad. I haven't slept through my alarm once since beginning my new job. It's also been beneficial to my anxiety and depression. Only other thing I'd look out for is weight gain. Over all Mirtazapine is a fantastic antidepressant that is very effective for sleep. I've been on it over a month and it still knocks me out. My life as a whole is also pretty drastically improved despite losing my job that I enjoyed and having to work a shitty job in the mean time
 
Other things that help for me is no coffee after 1pm, no screens before bed, lots of exercise during the day. But the main thing that helped me is looking at sleepless hours as bonus time that I get to read while all of those suckers in the world are unconscious.

Maybe there's a shred in there that's helpful for you, maybe not. Everything's different for everyone.

Yeah, coffee is part of the problem I guess, when I get shitty sleep I will typically drink coffee to get me through the day and I guess that's also affecting my sleep. It's kind of a vicious cycle. After a couple of hours trying to go back to sleep I always feel tempted to just get up and start my day earlier, but a part of me just keeps hoping to just fall back asleep. I guess I could just embrace it and read or do smething else like you suggested. If I manage to hold off coffee the day after, then maybe my sleep cycle will regulate itself at some point.

It's funny, when I'm in bed trying to keep my mind shut it will start coming up with music ideas or verses of some random shit. Sometimes I have Haikus come at me spontaneously lol. The other day my restless mind wrote this one:

Eyes are feeling dry
Just another sleepless night.
I hear birds singing.


(Originally it was in spanish but I managed to translate it and keep the correct amount of syllables lol)

So yeah, actually your post was super helpful, maybe going with the flow is the way to go.


I have always been a night owl, I hate even attempting to go to bed before midnight, and without medication I typically naturally fall asleep around 4-6am.

I can totally relate. Back when I was in College, at some point I realized my most productive study hours were between 9 pm and 1 am. That was the moment I was feeling more motivated, energized and mentally sharp. Thing is, I also always tried to religiously get at least 7h of sleep if possible, usually 8. So I would typically go to bed around 1:00/2:00 am and when I had classes before 10 am I would usually just skip them and study the subject later, at home, unless it was something mandatory like a practical lab lesson or an exam, etc. So I adjusted all my schedule and was able to get away with it just fine. When I started working with a contract it was painful trying to go back to "normal" schedule. I'm kinda lucky though that I work in research, where working hours are usually a bit more flexible. But if I had to be early at strict hours then I would probably also get fired lol. I've sure been there sleeping till a bit later to make up for a shitty night of sleep and then ending up being an hour late at the lab.
 
I’ve always been a night owl and just kinda ended up in a 6pm-6am shift job and that works okay for me, except there’s a lot more noise in the daytime so things wake me up whether it’s a car driving by or my cats chasing each other and stomping loudly.

On my days off I keep the same schedule and wake up at 4pm and go to sleep at 6-8am. That also works but anytime I need to do a functional activity like see a doctor or go shopping it greatly disturbs my sleep pattern.
 
One of my Lophophora diffusa plants was beginning to rot, so I cut the rot out and ate 23g of wet cactus that was remaining. Excited to see if a microdose of a non-mescaline containing peyote has any effect. Has anybody here ever done similar?

Edit: My last (and only other) peyote experience involved over 120g of wet matter that I dried and capped, but this one tasted so good I just munched it without any need for dehydration or powderization. The last experience involved a couple Lophophora williamsii plants too, but it was insanely powerful, maybe one of the most intense, and significant trips of my life.

Edit: I had first alerts within an hour, it's 3:45 later now and I think I've discovered what threshold dosing peyote feels like? It's a fascinating body feel, like I could hike for hours without getting tired. At the same time, I'm yawning as if I'm on mushrooms. There are mild visuals, the kind I'd get from half a tab of acid off the street if that makes sense. My body feels like my bones are all connected via super tough cabling in a way that's difficult to describe. Even more inarticulable is the fact that I feel like the present is drenched in a sense of nostalgia, as if I can tell that I'll be looking back at this moment in time fondly, at some point in the future.
 
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One of my Lophophora diffusa plants was beginning to rot, so I cut the rot out and ate 23g of wet cactus that was remaining. Excited to see if a microdose of a non-mescaline containing peyote has any effect. Has anybody here ever done similar?

Edit: My last (and only other) peyote experience involved over 120g of wet matter that I dried and capped, but this one tasted so good I just munched it without any need for dehydration or powderization. The last experience involved a couple Lophophora williamsii plants too, but it was insanely powerful, maybe one of the most intense, and significant trips of my life.

Edit: I had first alerts within an hour, it's 3:45 later now and I think I've discovered what threshold dosing peyote feels like? It's a fascinating body feel, like I could hike for hours without getting tired. At the same time, I'm yawning as if I'm on mushrooms. There are mild visuals, the kind I'd get from half a tab of acid off the street if that makes sense. My body feels like my bones are all connected via super tough cabling in a way that's difficult to describe. Even more inarticulable is the fact that I feel like the present is drenched in a sense of nostalgia, as if I can tell that I'll be looking back at this moment in time fondly, at some point in the future.
Interesting. So, here's a list of alkaloids present in Peyote: https://isomerdesign.com/pihkal/browse/collection/peyote-alkaloid

Or in no particular order: Tyramine, Dopamine, n-Methyltyramine, GEA, N-Methyldopamine, MDPEA, 3,4-DESMETHYL, Hordenine, 3,4-DMPEA, N-Me-GEA, 3-DESMETHYL, LOPHOPHINE, Candicine, MM-GEA, N,N-Me-MDPEA, N-Me-3-DESMETHYL, Mescaline, Anhalamine, Isoanhalamine, N-Formyl-3-demethylmescaline, N,N-Me-3-DESMETHYL, METHYL-MESCALINE, Anhalidine, Anhalinine, Anhalonidine, Isoanhalidine, Isoanhalonidine, Anhalonine, N-Acetyl-3-demethymescaline, N-Formylmescaline, N-Formylanhalamine, Peyoxylic acid, Anhalotine, Isopellotine, O-Methylanhalonidine, Pellotine, Lophophorine, N-Acetylmescaline, N-Acetylanhalamine, N-Formylanhalinine, N-Formylanhalonidine, N-Formylanhalonine, Mescaloxylic acid, Peyoruvic acid, O-Methylpellotine, Peyotine, Lophotine, Peyophorine, N-Formyl-O-methylisoanhalonidine, N-Acetylanhalonine, Peyoglutam, Mescaloruvic acid, Mescalotam, Mescaline succinimide, Mescaline maleimide, Mescaline malimide, Peyonine, Peyoglunal, Mescaline isocitrimide lactone, Mescaline citrimide. 😀🤙
 
Interesting. So, here's a list of alkaloids present in Peyote: https://isomerdesign.com/pihkal/browse/collection/peyote-alkaloid

Or in no particular order: Tyramine, Dopamine, n-Methyltyramine, GEA, N-Methyldopamine, MDPEA, 3,4-DESMETHYL, Hordenine, 3,4-DMPEA, N-Me-GEA, 3-DESMETHYL, LOPHOPHINE, Candicine, MM-GEA, N,N-Me-MDPEA, N-Me-3-DESMETHYL, Mescaline, Anhalamine, Isoanhalamine, N-Formyl-3-demethylmescaline, N,N-Me-3-DESMETHYL, METHYL-MESCALINE, Anhalidine, Anhalinine, Anhalonidine, Isoanhalidine, Isoanhalonidine, Anhalonine, N-Acetyl-3-demethymescaline, N-Formylmescaline, N-Formylanhalamine, Peyoxylic acid, Anhalotine, Isopellotine, O-Methylanhalonidine, Pellotine, Lophophorine, N-Acetylmescaline, N-Acetylanhalamine, N-Formylanhalinine, N-Formylanhalonidine, N-Formylanhalonine, Mescaloxylic acid, Peyoruvic acid, O-Methylpellotine, Peyotine, Lophotine, Peyophorine, N-Formyl-O-methylisoanhalonidine, N-Acetylanhalonine, Peyoglutam, Mescaloruvic acid, Mescalotam, Mescaline succinimide, Mescaline maleimide, Mescaline malimide, Peyonine, Peyoglunal, Mescaline isocitrimide lactone, Mescaline citrimide. 😀🤙
This is actually the specific reason I'm so interested in Lophophora fricii and diffusa, they're super rich in this wide variety of alkaloids, whereas williamsii is moreso focused on mescaline. Mescaline grows faster in other cacti anyways, and I'm not going to lie, a single button of this was at least threshold, once I'm cultivating on a larger scale I may start doing that once or twice a week, just eat a 3" button to get my day started.

I didn't end up mixing it with anything, but my temptation to eat some DOB right now is large. Instead though I'm sipping on some etizolam in a powerade, and puffing on a box mod I just made of 780ug/mL MDMB-4en-PINACA.
 
Mescaline grows faster in other cacti anyways
So, the move to make is to graft a peyote plant on to the stump of a healthy, freshly harvested San Pedro (aka: Peruvian Torch cactus). Once grafted, the peyote will grow at the rate of the San Pedro and reach full maturity in approx. 2 - 3 years instead of the usual ~125 years. They say never to touch wild peyote in the desert growing on its own. Those are super rare. Instead buy peyote from a peyote harvesting farm where they're grown for human consumption on the Peruvian Torch cactus described above. I imagine the scene for finding peyote in the U.K. is challenging and rare… It's not super easy to find in the U.S., but it definitely grows, and is harvested, out west – Southern California, Utah, Nevada, New Mexico, Arizona, Colrado, in that general area.

but my temptation to eat some DOB right now is large.
That just reminded me: I have some DOM tabs to gobble up. I have DOB tabs as well, but motherfuck that body load, lol.
 
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So, the move to make is to graft a peyote plant on to the stump of a healthy, freshly harvested San Pedro (aka: Peruvian Torch cactus). Once grafted, the peyote will grow at the rate of the San Pedro and reach full maturity in approx. 2 - 3 years instead of the usual ~125 years. They say never to touch wild peyote in the desert growing on its own. Those are super rare. Instead buy peyote from a peyote harvesting farm where they're grown for human consumption on the Peruvian Torch cactus described above. I imagine the scene for finding peyote in the U.K. is challenging and rare… It's not super easy to find in the U.S., but it definitely grows, and is harvested, out west – Southern California, Utah, Nevada, New Mexico, Arizona, Colrado, in that general area.


That just reminded me: I have some DOM tabs to gobble up. I have DOB tabs as well, but motherfuck that body load, lol.
DOB body load definitely ruins many people, after I spent 8-10 months using ayahuasca daily though body load is very minimal for me from anything, it seems.

You have a great point about grafting, I'm obsessed with Lophophora cultivation and the community at large rn agrees that a year from seed to seedling, a year grafted, then one more year degrafted growing a strong taproot leads to a psychoactive button that can be crown harvested for sustainable harvest.

Not to be nitpicky but just for future readers, there's an incredibly minute difference between San Pedro cacti (Trichocereus pachanoi), and Peruvian Torch cacti (Trichocereus peruvianus). Torches tend to be more potent, both can be solid grafting stock but most people use Scoplicula cacti, I'm not sure if that leads to a potency difference in the end. Torches sell for much more than San Pedro too, and they have vaguely different appearances but they can be nearly impossible to tell apart.

Sorry for the rant, I'm just a huge cactus nerd and love talking about it.
 
DOB body load definitely ruins many people, after I spent 8-10 months using ayahuasca daily though body load is very minimal for me from anything, it seems.
Perhaps you've caused yourself some monoamine downregulation during your heavy ayahuasca use period.

You have a great point about grafting, I'm obsessed with Lophophora cultivation and the community at large rn agrees that a year from seed to seedling, a year grafted, then one more year degrafted growing a strong taproot leads to a psychoactive button that can be crown harvested for sustainable harvest.
I kinda thought you might already be hip to the technique.

Not to be nitpicky but just for future readers, there's an incredibly minute difference between San Pedro cacti (Trichocereus pachanoi), and Peruvian Torch cacti (Trichocereus peruvianus). Torches tend to be more potent, both can be solid grafting stock but most people use Scoplicula cacti, I'm not sure if that leads to a potency difference in the end. Torches sell for much more than San Pedro too, and they have vaguely different appearances but they can be nearly impossible to tell apart.

Sorry for the rant, I'm just a huge cactus nerd and love talking about it.
I don't think it's all that clear cut though. Like you pointed out: they can be hard to distinguish.

"Trichocereus macrogonus, synonym: Echinopsis macrogonus, is a species of cactus found in Ecuador, Peru and Bolivia. Two varieties are accepted as of September 2023: var. macrogonus and var. pachanoi. Plants contain varying amounts of the psychoactive alkaloid mescaline. They have been used both ritually and in traditional medicine from pre-Columbian times. Trichocereus macrogonus is one of a number of similar species that may be called San Pedro cactus. Indigenous names include achuma and huachuma, although these too may be applied to similar species."

Though you're right – it probably is worth distinguishing between these. There are multiple factors though affecting alkaloidal content, ya know…
 
Not to be nitpicky but just for future readers, there's an incredibly minute difference between San Pedro cacti (Trichocereus pachanoi), and Peruvian Torch cacti (Trichocereus peruvianus). Torches tend to be more potent, both can be solid grafting stock but most people use Scoplicula cacti, I'm not sure if that leads to a potency difference in the end.

Pedros, torches, and scops all interbreed don't they? My guess is that other factors including specific genetics and conditions of growth/harvest are more important than the particular species. I really don't know though and wish more good information was available on these things. The claims that Peruvian Torches tend to be stronger than San Pedros almost all refer to some person's opinion. IIRC, I saw a systematic study done in which samples of many different cacti were acquired and the most potent sample was actually a San Pedro bought at a Peruvian market.

I recently started a collection consisting of scop and scop hybrids. I also started a bunch of seeds, but of course those are much harder to keep alive. I've eaten 4 different kinds/sources of cacti now, and they all felt a bit different. Knowing I have a limited supply of my favorite stuff, I'm hoping I can find something else I like if I have enough different genetics to choose from.

I don't really know, but if I had to guess, grafting won't affect potency or alkaloid composition of a peyote much if any. Surely by now at least some people have analyzed peyote grown on grafts and can give a more sure opinion than I. Anyway, I have heard very little about the potency or effects of scopulicola cacti compared to the others. If I understand right, it's more closely related to bridgesii than the others, whatever that implies.
 
Pedros, torches, and scops all interbreed don't they? My guess is that other factors including specific genetics and conditions of growth/harvest are more important than the particular species. I really don't know though and wish more good information was available on these things. The claims that Peruvian Torches tend to be stronger than San Pedros almost all refer to some person's opinion. IIRC, I saw a systematic study done in which samples of many different cacti were acquired and the most potent sample was actually a San Pedro bought at a Peruvian market.

I recently started a collection consisting of scop and scop hybrids. I also started a bunch of seeds, but of course those are much harder to keep alive. I've eaten 4 different kinds/sources of cacti now, and they all felt a bit different. Knowing I have a limited supply of my favorite stuff, I'm hoping I can find something else I like if I have enough different genetics to choose from.

I don't really know, but if I had to guess, grafting won't affect potency or alkaloid composition of a peyote much if any. Surely by now at least some people have analyzed peyote grown on grafts and can give a more sure opinion than I. Anyway, I have heard very little about the potency or effects of scopulicola cacti compared to the others. If I understand right, it's more closely related to bridgesii than the others, whatever that implies.
You've got this all down right imo, the current landscape is so full of misidentified samples, taxonomical mishaps, as Sasha Shulgin said, "there's nothing more difficult than identifying a cactus".

In reference to: "Perhaps you've caused yourself some monoamine downregulation during your heavy ayahuasca use period." (Sorry, can't quote it right, on my phone rn), I've been suspicious of this but I've been extremely sensitive to MAO is and serotonergics since this period, but without the nausea and body load to the same degree. The headspace, visuals, and sensory alterations to other senses all increased and never really deteriorated. I've used harmaline since to recover from eating a fifth of a sheet of 25C-NBOMe in a month maybe two years ago, and I have a strong feeling that 5-MeO-DiPT creates a weirdly subtle, long term tolerance that's leading me into a phase of microdosing again from today through August to see where my threshold lies.

Currently I'm going to be microdosing DOB at 325ug until 6/19, then N,N-DiPT at 12mg, and finally allylescaline at 10mg, each for eighteen days (6 doses, one every 3 days) with a week in between each substance, to let tolerance reset. I've already become familiar with microdosing LSD, LSA, psilocybin containing mushrooms, psilacetin, ketamine, 5-MeO-DiPT, peyote for a single dose recently, harmaline, DMT, DPT, 2C-B, DOM, DXM and salvia. Microdosing trials with MDA and MDMA were interesting but almost certainly unhealthy. I've also played with how low of a dose I can gain benefit from with countless benzos, amphetamine, GHB , Soma, methamphetamine, phenidates, really everything, as a drug nerd I find a ton of value in getting to know substances both in threshold doses as well as higher ones.

Sorry for being intermittent recently, my former phone was physically trashed and my new one managed to get my email locked, so I'm only able to access BL from my phone until tomorrow when my email account gets recovered.

What interesting strategies for microdosing have people here used?

I've experimented with alternating psilocybin containing fungi with HBWR, but it led to an "Oh my that wasn't a microdose!" moment while driving in some mild mountains in Maine. So far 2C-B, DXM, peyote, and DOM have been absolutely fascinating, 2C-B being the shining star as it can be used daily, but the afterglow is very short compared to other substances I've used. Also important to mention here, I tend to find a dose that's just barely at threshold the most effective for me, many others only use the term microdosing to refer to sub-threshold doses.
 
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I found a small handful of Panaeolus cyanescens the other day strolling through a pasture - I'm guessing around 3-5mg of psilocybin worth, so not quite enough for a trip, but it's got my eyes peeled for more 👀

What interesting strategies for microdosing have people here used?
I've microdosed "acids" the most - LSD, 1p-LSD, AL-LAD, ETH-LAD and then a bit of 2C-P, 2C-E, 2C-D, 2C-I, and a handful of tryptamines. And mushrooms. I'm more conservative than you for microdosing - at most 2 days in a row, more often 1 day on 6 days off. I like taking just a notch past microdose level so that I'm actually threshold tripping a tiny bit - in that area between microdose and threshold. I would probably microdose more often but I'm slightly concerned with cardio vulvopathy risk from chronic 5ht2b stimulation. With this in mind mushrooms are a good contender for microdosing because I believe they have a high ratio of 5ht2a:5ht2b agonism - and also because there will probably be mountains of data on mushroom microdosing over the near future because it must be the go-to for most microdosers out there.

I love microdosing and running on mountain trails. For work I get a bit too entranced with music and become a bit too loose to regard it as a useful productivity boost the way that coffee is, but I have had some breakthroughs using it in work context because it can give a more birds-eye-view, 3rd person perspective, and a more creative and inspired attitude. It can just as easily completely distract me from work and remind me to do more of the joyous things in life like make music, go for a run, hang out with my kids.
 
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