N&PD Moderators: Skorpio
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klfiend
Bluelighter
Looked like a dumb drug when I saw it come out. Glad your off it OPunodelacosa
Bluelighter
Muy interesante. Did you try this particular one?
ELIZA
N-mono-ethyl-lysergamide
Inspired by L-theanine and Anandamide.
Rectify
Bluelighter
NEO_NOVOCAINE
2-(dimethylamino)propyl-4-aminobenzoate
DESIGNER_NOVOCAINE
2-(dimethylamino)propyl-3,4-methylenedioxybenzoate
I'm Not Kidding.unodelacosa
Bluelighter
Yeah me, too. … for science, of course.
That should be the official motto of some psychotropic-drug-related academic institution: “Pro Scientia, Utique”
Das ist Lustig
dimethyl ether
—.— I see what you did there ![]()
I am somewhat reminded of the SSRI antidepressant, Paxil (Paroxetine), or as I like to call it: PAXSTASY
2-(dimethylamino)propyl-3,4-methylenedioxybenzoate
I'm Not Kidding.
It's that 3,4-methylenedioxy ring attached to an oxygen atom that serves as a negatively charged source of "selective" pharmacodynamics, or what's referred to as "enantiomeric shielding".Rectify
Bluelighter
1-phenyl-1-carboxy-2-methylaminopropane
LAH, THF
1-(hydroxymethyl)-2-methylamino-1-phenylpropane
O-methylation
CLEVER_AS_EVER
1-(methoxymethyl)-2-methylamino-1-phenylpropane
I dunno necessarily about activity, but the MOM (methoxymethyl) functional group works for sufentanil.Rectify
Bluelighter
THE_LOWER_48
1-(3,4,5-tris(trifluoromethyl)phenyl)-2-aminopropane
SLICK_50
1-(3,4-bis(trifluoromethyl)phenyl)-2-methylaminopropane
I highly recommend opsin.ch.cam.ac.uk
I just wrote and accidentally erased a huge paragraph on how to use opsin. It took me a whole day to learn, but I'm glad I did.
If you want, I will write it out again.smokeymcpot42088
Bluelighter
In the US there is a medication called "lybvaldi" being heavily advertised "ask your doctor" included. It is a compound of Olanzapine/Samidorphan (naltrexone analog, causes PWD)
They are also doing this with Buprion/Naltrexone and a couple weight loss meds. The official line of reasoning is to control weight gain; I don't know that I believe for one second that is why they are adding it. Anyone agree with this logic or is this just a "lets screw everyones receptors over" scheme?
Any thoughts?Jabberwocky
Frumious Bandersnatch
ihaveacoolcat
Greenlighter
TheLightBringer
Bluelighter