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  • Trip Reports Moderator: Xorkoth

Started microdosing shrooms today for depression.

Woke up feeling depressed. Took 50mg shrooms with my coffee and Suboxone. 1.5 hours later, I don’t feel as depressed.
 
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But now you're taking it everyday, which you're not meant to do with a microdose for treating depression, or the subs helped you feel better
 
Felt horribly depressed from 5pm-10pm tonight. My depression is not getting better.
 
Opi_Kid_Rock said:
I haven’t been successful in treating my depression with the shrooms I have. I feel like giving up on the whole process. Anyone on here have success stories?
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Unless I'm missing something it seems like you've only been microdosing for a week, don't you think you might be expecting a bit much a bit soon? My experience with microdosing has been that its helped me identify the obstacles in my life that are making me unhappy but its been on me to take the initiative to make the changes needed to address those issues. I think the microdose may have elevated my mood somewhat and I certainly feel like its made me more empethetic. Most of the benefits I've experienced however have come as a result of the introspection that psychedelics seem to facilitate and any changes to the way I think have occurred over a period of weeks and months not days.

I'm also a little concerned that you seem to be taking it every day? Even at low doses you're going to build a tolerance that way. 4 days on 3 days off is what I did at 200mg and the 3 days off seemed to be enough to reset my tolerance.

Out of curiosity, have you ever tried a full psychoactive dose of psilocybin mushrooms (1.5g+) or has it just been microdosing so far? While there has been a fair bit of research lately into using psilocybin for treatment resistent depression, most (all?) of it has focussed on macrodoses in combination with therapy. Unfortunately, aside from anecdotal evidence based on user reports we just don't seem to know much about how effective microdosing is as a treatment for depression.
 
Shinji Ikari said:
Unless I'm missing something it seems like you've only been microdosing for a week, don't you think you might be expecting a bit much a bit soon? My experience with microdosing has been that its helped me identify the obstacles in my life that are making me unhappy but its been on me to take the initiative to make the changes needed to address those issues. I think the microdose may have elevated my mood somewhat and I certainly feel like its made me more empethetic. Most of the benefits I've experienced however have come as a result of the introspection that psychedelics seem to facilitate and any changes to the way I think have occurred over a period of weeks and months not days.

I'm also a little concerned that you seem to be taking it every day? Even at low doses you're going to build a tolerance that way. 4 days on 3 days off is what I did at 200mg and the 3 days off seemed to be enough to reset my tolerance.

Out of curiosity, have you ever tried a full psychoactive dose of psilocybin mushrooms (1.5g+) or has it just been microdosing so far? While there has been a fair bit of research lately into using psilocybin for treatment resistent depression, most (all?) of it has focussed on macrodoses in combination with therapy. Unfortunately, aside from anecdotal evidence based on user reports we just don't seem to know much about how effective microdosing is as a treatment for depression.
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Fair enough I haven’t been taking the proper days off and haven’t dosed long enough. I have taken macro and heroic doses in the past before. My depression hasn’t gotten better over the years.
 
Opi_Kid_Rock said:
Fair enough I haven’t been taking the proper days off and haven’t dosed long enough. I have taken macro and heroic doses in the past before. My depression hasn’t gotten better over the years.
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Understood. While it may be anecdotal many users have reported an improvement in depression symptoms from microdosing so I think it's worth sticking with. I'm not a mental health expert and my microdosing experience was for different reasons (partly personal development partly looking for alternative treatments for my ADHD) so I'm hesitant to offer my advice, but perhaps for the sake of consistency and better being able to document any changes you'd consider one of the established protocols?

I did the Stamets stack with 200mg psilocybin mushroom and 1g lions mane mushroom (I didn't bother with the niacin and reduced the lions mane dose because I'm not made of money) with 4 days on and 3 days off to reset tolerance. There are other protocols you can try, some I feel are more suited for microdosing LSD (such as the Fadiman protocol) while others have been formulated solely with mushrooms in mind. More info on the established protocols here.

Depression is complicated and there is no magic bullet but many people have found psychedelics helpful in one way or the other. I hope you find the answers you're looking for sooner rather than later.

Stay strong friend
Shinji
 
So today will be my last post for this thread. A few conclusions that I’ve discovered: I did not experience immediately healing effects of my depression as the news/Internet hype would have one to expect. If this is supposed to be some kind of long-term solution to depression, then I haven’t reaped the benefits yet and will try for a half year or full year to see it through. My hopes arn’t high at the moment about its possible success.
 
Just thought I'd ask, have you tried different types of anti depressants? It took me years to finally fine one that suits my physiology.
And luckily I can still use drugs without any loss of effects, although I do seem to need more of the drug to get the desired effect.
 
As Shinji said you went a week… You’re expecting too much too soon from too little. It takes at least 2weeks for the neurogenesis to even start to kick in, that’s why SSRI’s take a couple weeks too otherwise they’d work immediately.

To be honest this is most definitely not a magic bullet, this is a door to a better life, you got open it and walk through.

I personally think microdosing is overrated though, youll get much more from low to medium dosing and not have to use it so much either.

-GC
 
I assume you meant 50mg of mushrooms, not of psilocybin... 50mg of pure psilocybin is very large fully psychedelic ego shattering dose. :) But yeah, that is quite low for a microdose, usually I like to do 200mg of a microdose of mushrooms. I find it lends me clarity of thought and a mental/emotional boost, without any amount of intoxication or high/trip. It's quite lovely.
 
i had fantastic results helping me resolve ptsd. i used small doses of picamilon as the niacin source and it seems to be nice to have the extra GABA effect. 5 years of suffering from clinical PTSD. i have done maybe 6 weeks total, currently off cycle. I had an extremely triggering event happen that would usually have wrecked me for several months... I'm mostly recovered at 48 hours. that is a sea change difference.
 
Opi_Kid_Rock said:
I have suffered my whole life with treatment-resistant major depressive disorder. Big-pharma-antidepressants didn’t work on me. On Suboxone but I was never feeling naturally at peace nor my reoccurring thoughts all that positive either. Practicing regular meditation has always been a real challenge for me.
Today I took what I eyeballed to be 50 milligrams of psilocybin. Let me read the label here, “Psilocybin Cubensis, Golden Teacher, Lions Mane, Niacin, Ginger capsules 500milligrams/capsule.” I have always been the physiologically sensitive type. Just starting my day here and I notice I have an appetite to eat. Nature looks more beautiful. I am not bombarded by reoccurring negative thoughts at this moment. I feel more naturally energized which is very surprising to me; as a former opiate-addict energy has always been a problem in my life. It is 11:00am for me right now and I still have the whole day ahead of me. I will update my journey regularly. I just had to find out on my own whether microdosing shrooms and its purported benefits were true. I want to be skeptical and open-minded at the same time. It has been recommended that I dose about once every three days according to some sources. I am open to any thoughts and recommendations or to hear about your experiences microdosing different substances.
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Opi_Kid_Rock said:
I have suffered my whole life with treatment-resistant major depressive disorder. Big-pharma-antidepressants didn’t work on me. On Suboxone but I was never feeling naturally at peace nor my reoccurring thoughts all that positive either. Practicing regular meditation has always been a real challenge for me.
Today I took what I eyeballed to be 50 milligrams of psilocybin. Let me read the label here, “Psilocybin Cubensis, Golden Teacher, Lions Mane, Niacin, Ginger capsules 500milligrams/capsule.” I have always been the physiologically sensitive type. Just starting my day here and I notice I have an appetite to eat. Nature looks more beautiful. I am not bombarded by reoccurring negative thoughts at this moment. I feel more naturally energized which is very surprising to me; as a former opiate-addict energy has always been a problem in my life. It is 11:00am for me right now and I still have the whole day ahead of me. I will update my journey regularly. I just had to find out on my own whether microdosing shrooms and its purported benefits were true. I want to be skeptical and open-minded at the same time. It has been recommended that I dose about once every three days according to some sources. I am open to any thoughts and recommendations or to hear about your experiences microdosing different substances.
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Use to microdose shrooms a few times at doses around 500mg dried semilanceata.Not much impression cause i stop it too soon.It feels me kinda tired and lazy.Always prefer a good 2g full blown trip on mushrooms when i am at good mood for tripping.Prefer iboga for microdose.But I am sure that microdosing shrooms is an effective way to treat various conditions like depresssion,cluster headaches...etc.
 
Nas47 said:
Use to microdose shrooms a few times at doses around 500mg dried semilanceata.Not much impression cause i stop it too soon.It feels me kinda tired and lazy.Always prefer a good 2g full blown trip on mushrooms when i am at good mood for tripping.Prefer iboga for microdose.But I am sure that microdosing shrooms is an effective way to treat various conditions like depresssion,cluster headaches...etc.
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500mg is a low dose, not a microdose. The goal of a microdose is to not feel the drug, but rather just produce a subtle change in thought process and mood. Try 100mg sometime. Low sub-tripping doses of psychedelics can often feel negative due to feeling the side effects but not really enough to get the positive effects. However a true microdose avoids this as it is too low to feel any of the acute effects.
 
You are absolutely right ofcourse.But first thing is to escape from that circle again-going through withdrawls.Cannot imagine withdrawling with microdose.That is something that would help with PAWS.500mg dose is somewhat near to booster dose than micro thats right.At the end I am currently taking low dose zoloft that also must quit before to start microdosing.Thank you for your reply.Wish you joyfull day
 
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