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Mental Health Coming off Invega Sustenna (Paliperidone) v3

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PhucInvega said:
I promised myself that next week I'll start exercising my fat ass back to shape. I'm gonna burn every single fat cell infested by invega to prove you guys that exercise is a crucial step towards full recovery from this literal poison. I'm also going to order the highest grade St. John's Wort I could find on Monday to see myself if the P-gp induction by SJW will actually help to get rid of invega, like in theory it should. CBD and other cannabinoids should also induce the same protein but I've found mixed results on the studies, some say they inhibit it but some say they induce it, so I'm going to use it on top of the SJW anyway. I'm going to post some proggies at least once a month for you guys to see if I really achieved anything or just made a fool out of myself. Today I'm going to smoke my hopefully last cigs too. It's time to get my life back on track!
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Exercise helps for the day but then you gotta do it again next day. For a few months I used to do intense cardio and weights everyday. I burnt fat, made muscle but in the end I noticed no mental improvement over long term.

There were many anecdotal placebo stories of St. John's Wort, so I understand why you want to test that bro science. Try 2100mg of high quality SJW and you will feel how it actually works then realize that SJW is annoying AF and not worth that long term relationship! However, I wish you persistence and luck just like this user that started to notice real subtle effects after a year of 1800mg SJW daily.

Quitting cigarettes: It helps if you quit weed at the same time because it's hard to control cravings while high. You won't sleep when you quit cigs anyways, so might as well quit both since it doesn't make it any harder.
 
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For those of you that had a terrible time on and after invega sustenna...what dosage were you on? and for how long?
 
raerae19 said:
For those of you that had a terrible time on and after invega sustenna...what dosage were you on? and for how long?
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Medical websites will tell you there are not enough long term scientific studies following cessation of long-acting anti-psychotics like Invega Sustenna, Risperdal Consta, Abilify Maintenna, or even pill/capsule drugs like Vraylar. (My advice is to do research into the drug your P-doc wants to prescribe before agreeing to taking it). With that said, med-experts on websites advise that you keep a journal to record your progress. 90 days is kind of a staple number for seeing how your symptoms compare to what they were immediately after withdrawing. Withdrawals can be severe. In fact, some withdrawal symptoms can mimic and even seem to trump the symptoms that were there prior to stopping. That's why they advise to not-quit-cold-turkey. There are various websites that offer a quick half life calculator-equation to get a gander at how long you might expect to wait for symptoms to subside but honestly, the accuracy of these is questionable considering a number of factors like you mention (length of time spent on the drug). As far as I can see there is not a very accurate way to see how long a withdrawal stage will last before symptoms completely subside. You could type into the calculator on a website 3 mg Vraylar for example and find that the half life period to get to zero is approximately 6 months, but that won't tell you much of anything if you were taking it for, let's say, a month.- save for the fact that obviously the duration would be longer than 6 months, but how long?

I've posted in here, I think, before about the importance of keeping a log or a journal. If you journal about your symptoms every few days or so, you can look back later and get kind of an understanding of how far you've come along. I get it. It's kind of stupid compared to what we want to see. We want a general sense that the future is better than going through a lot of this mess. So what can we do to speed up the process??

Diet, exercise, changing routine, changing lifestyle, losing weight, becoming more fit - these things can certainly help, but the motivation, especially with Invega Sustenna is not... necessarily... there... is it?

If there is any one positive benefit to being stuck on Invega Sustenna it may be this: you may find yourself with more wasted time on your hands on Invega Sustenna and the other drugs I've listed than any other drug on the soul-harvesting market so take this into consideration at least: if you spend this time on Invega researching and learning as much as you possibly can it may benefit you significantly later. I've spent roughly 7 of the last 8 years under the heavier effects of these drugs and I have actually learned a TON of information - information that can benefit me now and later.

As a kind of side note, though. Some of this "withdrawal" stuff isn't really predetermined. It's probably possible that any of you, at any time, could suddenly wake up with a new perspective and possibly even forget that you were ever on it in the first place. That's one of the reasons why I include that ^ last paragraph. Some things that you may encounter in books that are particularly spiritual for example could change your life significantly. It's all about whether or not you are prepared to walk the path and how steady you feel trying to get at it. Certain spiritual information can be as useful as weeks spent withdrawing from Invega and expecting to recover.
 
Some people who are suffering somewhere around the world will take one day take a lawsuit or some measures to punish the producers of invega sustenna.

I can't wait for the day this product makes the headlines for being one of the worst drug ever created. And be finally taken away from the market.
 
bunnyrabbit528 said:
Exercise helps for the day but then you gotta do it again next day. For a few months I used to do intense cardio and weights everyday. I burnt fat, made muscle but in the end I noticed no mental improvement over long term.

There were many anecdotal placebo stories of St. John's Wort, so I understand why you want to test that bro science. Try 2100mg of high quality SJW and you will feel how it actually works then realize that SJW is annoying AF and not worth that long term relationship! However, I wish you persistence and luck just like this user that started to notice real subtle effects after a year of 1800mg SJW daily.

Quitting cigarettes: It helps if you quit weed at the same time because it's hard to control cravings while high. You won't sleep when you quit cigs anyways, so might as well quit both since it doesn't make it any harder.
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I'm not going to use SJW for curing depression since I'm not even depressed, instead I want to see if the P-gp protein induction will help to get rid of invega from the brain tissue. Like I've said many times previously, 60% of brains volume is fat and paliperidone is fat-soluble. Exercising only burns the fat off your body but it won't affect the cells in the brain. That's why you didn't notice any mental improvement. When you exercise and burn the fat off your body which invega is also stored in, the substance will get released into the bloodstream, and from the blood it will cross the blood-brain barrier and enter your brain. So basically exercising could potentially make you feel even worse since the paliperidone stored in your body will move to your brain instead.

One of P-gp's functions is the transport of compounds out of the brain across the blood–brain barrier. So once you induce the protein with SJW and exercise to burn the fat off your body, then even though the substance gets released into blood, it won't be able to cross the BBB and enter the brain. Also another function of P-gp is the removal of toxic metabolites and xenobiotics from cells into urine, bile, and the intestinal lumen, and since paliperidone palmitate is mostly renally excreted this might speed up the removal of paliperidone. And I'm not really sure what you meant with the 'bro science'. If you already knew this basic bro science then why didn't you use a P-gp inducer whilst you were exercising to maximize the potential of detoxifying? And isn't it kinda obvious that exercise helps for the day but you gotta do it again the next day? Same goes for eating food and taking a shit.
Also I'm not going to quit cigs cold turkey, I'm switching to a vape instead and I'm going to reduce the amount of nicotine in the liquid gradually. It's not even healthy to quit a psychoactive substance cold turkey after using it for >10 years. And personally when I'm high my desire for cigs decreases by a great degree.
 
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Hey I’m calling out again in hopes someone has had muscle stiffness from this drug and what may have helped? As well I have the urge to urinate often and pain in the knees, stiff ankles, ringing in the ear, can’t nap during the day.

Also, for those not sleeping I have found taking 300mg magnesium glycinate gets me 4hrs sleep and then 300mg more gets me another 2hrs. Sometimes I sleep another hour or rest deeply. If I don’t take magnesium I don’t sleep.
 
Day 43

I am experiencing some mild happiness and social connection. I've poured through several articles on politics and world news, read a book, and watched the latest episode of Democracy Now! Although physically there are still elements of me that are dysfunctional (sexual dysfunction, especially), I feel that the last couple of days might mark a turning point. My mood is improving and I've been able to sustain work on the computer for decent amounts of time.

I hope there are similarly positive results for those on the thread. I know how difficult it can be to come off of this drug, but even the small improvements count.
 
Didn’t go to sleep last night. I don’t know what to do at this point. All I do is apply for jobs, look for detox’s online, and lay in bed. I just can not believe I’m a year n two months out with no improvement and everyone is starting to see improvement before then. I pray about this all day long but nothing has changed. I’m trying very hard. But this is like mission impossible right now. I just want to feel somewhat better. I wish there was some solution out here that I can discover and share outside of time.
 
I also found some detox products. There not specifically for antipsychotics but I wanted to share one with y’all and get yalls feedback.

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lifeline said:
Didn’t go to sleep last night. I don’t know what to do at this point. All I do is apply for jobs, look for detox’s online, and lay in bed. I just can not believe I’m a year n two months out with no improvement and everyone is starting to see improvement before then. I pray about this all day long but nothing has changed. I’m trying very hard. But this is like mission impossible right now. I just want to feel somewhat better. I wish there was some solution out here that I can discover and share outside of time.
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***mod edit: please don't advise others to start a new drug. Instead, "microdosing mescaline worked for me"***
 
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Pomegranate juice and pomegranate vinegar had made my condition 10 to 15% better. Now I am healed but I can't advise you to do the same. Good luck to y'all.
 
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I just don’t know what to do. I’ve had more than enough time to see some difference. I don’t get it. I just want my thoughts and emotions back. So I can get back to work.
 
zack365 said:
Pomegranate juice and pomegranate vinegar had made my condition 10 to 15% better. Now I am healed but I can't advise you to do the same. Good luck to y'all.
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I may try that. I wish I could speak to a few of those people on the list you created for recovery time. Would like to know if they saw improvement by now even if it took them longer to recover.
 
lifeline said:
Didn’t go to sleep last night. I don’t know what to do at this point. All I do is apply for jobs, look for detox’s online, and lay in bed. I just can not believe I’m a year n two months out with no improvement and everyone is starting to see improvement before then. I pray about this all day long but nothing has changed. I’m trying very hard. But this is like mission impossible right now. I just want to feel somewhat better. I wish there was some solution out here that I can discover and share outside of time.
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It was about 2 years and 8 months before I was about 98% back to normal
Also, my experience on Vraylar, which was kind of a 1 month trial period, has been kind of the same. The half life is about half that of Invega. I'm still recovering from that one.
 
iridescentblack said:
It was about 2 years and 8 months before I was about 98% back to normal
Also, my experience on Vraylar, which was kind of a 1 month trial period, has been kind of the same. The half life is about half that of Invega. I'm still recovering from that one.
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That’s crazy. Did you start to feel better before then though. That’s a long time and you are a soldier. How many injections did you have?
 
I had actually grown quite powerful, but my father tricked me into admitting myself to a hospital by promising I was only there to merely "talk" to someone. The amount of injections, I don't recall. If I had to guess I'd say it was something like 4-8 and that was immediately following a sort of recuperating period on Risperdal Consta.
 
*Successful Recovery Story*

Hey all, I used to post on this forum regularly while recovering from Invega. However, there were no success stories for me to read and it was ultimately just making me feel worse, I felt sorry for myself and for everyone else suffering.

I received two shots of invega in September of 2015. The first 3 months I felt unbelievably depressed and negative. The one thing that got me out of bed was having a Rottweiler who was sick and I needed to take care of her. Giver her meds, take her for walks/rides and to vet appointments regularly. I had to force myself. It wasn’t fair for her to suffer just because I was suffering. For the first 12 years of her lif I always helped her when she needed it. And unfortunately, I was going through recovery from Invega during the times when she needed the most help. It was a tough combination but we got through it. The vet recommended I put her down because he didn’t think I could take care of her. He was wrong. She lived for another 18 happy months from the day he said that.

It’s important to have something worth fighting for during this process. Wife, family, kids, pets, YOURSELF, etc.

One thing I always searched for were dates when I would feel better. By month 6 I had begun to work with a friend for 2-3 hours per day, twice per week. It wasn’t much but I was easing back into it. I was helping him with upholstery even though I’m actually a career mixed martial arts coach. Teaching and sparring with students was something that felt unbearable to do until about a full year post-shots.

By month 13, I did a full 8 week Mixed Martial arts training camp to prepare for a liv mma fight. You can look on my Facebook for proof. There is a poster dated February of 2017 with me on it for the PA Cage Fight event. So, September of 2015 until February of 2017 was how long it took for me to compete in mma again. But I started the training camp in December of 2016.

So, it was approximately 15 months until I was able to train Mma the way I was able to train before the invega shot.

As of March, 2019, I opened my own MMA and Fitness gym and started a Charity to support people with mental health issues. The online website is Patreon.com/MMAforCharity if anyone is interested in seeing what we do. Maybe it can help you see that there is tangible evidence of people who got better.

I am posting a long reply here because over 10 people have contacted me on Facebook asking about how I dealt with recovering from the invega shot. It is difficult to talk to everyone 1-on-1 daily, so I’m posting in the group.

2 of the 10+ people that contacted me said they feel fully recovered.

I need to point out that I STILL receive psychiatric treatment in the form of daily medications and pdoc appointments. I do NOT take invega anymore though.

This is the list of medications I am currently on.

Lamictal: 400mg
Prozac: 60mg
Adderall XR: 30mg
Klonopin 0.5 mg 3x per day or as needed.
Wellbutrin: 450mg per day.
Adderall: 20mg

I also take Kratom daily. Usually green and white stimulation strains. Even while going through recovery, Kratom was able to help me feel at least a little bit better.

Feel free to email me if you have questions. [email protected] or hmu on Facebook. My full name is a Justin Koslosky.

Stay strong. Invega recovery was the most difficult thing I’ve ever dealt with and it seemed like it was never going to end. And that’s because you ARE getting better with every passing day, but the progress takes place in such tiny increments that it’s almost unnoticeable until a long period of time has passed.

Keep an open mind to the possibility that you might need treatment. I’m sure some of you were misdiagnosed. Maybe you went into psychosis from a drug overdose or sleep deprivation. But even if that is the case, it is possible you may have a mental health condition now that will require treatment. If you have been off for over a year and don’t feel any better but are not receiving treatment then you should consider looking into getting some. In my opinion.

Everyone OUTSIDE OF THIS FORUM has been extremely understanding and kind to me about having mental illnesses. The cruel and insulting comments have come from people on this forum and patients in psychiatric hospitals who deny that they are “one of those crazy people.” It doesn’t make you crazy. And please realize you are insulting people who are simply trying to help you by explicitly calling people like them crazy. Even though you probably don’t realize it. It’s not really something to be embarrassed about anymore. There’s no shame in getting treatment.

YOU WILL RECOVER.

Regards,

Justin

P.S. Life isnt the movie V for Vendetta. Doctors didn’t secretly plot to ruin your life by spending 8-12 years in medical school and 200,000+ dollars just to shoot you up with poison and destroy your life. Tbh, that type of thought is the same type of irrational paranoia that Schizophrenia can cause.
 
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