Yeah, thinking about how much eye contact was made in general and whether I was acting in a way that didn't match the situation or not helping out were parts of my aversion at times. Each independently helped with my symptoms, though again, I worked with therapy and over time at getting in a healthier state and not overthinking things. I can't fully attribute all change to one particular drug, therapy, or experience. However, I did find myself less bothered with eye contact / social interactions with both medications separately.
MAOIs may not play nicely with some things, especially in some individuals, so you would have to be careful and not risk taking too much or especially polysubstance use. Some people can have amphetamines on MAOIs and are prescribed them even, as another poster already showed, but your individual response may be more drastic. Some individuals can't even tolerate caffeine on them or have side effects.
Would have to be very slow and careful with doses of anything, and shrooms would have to be monitored and likely would be quite risky. I didn't have caffeine for a few months on it, but later resumed my usual 2-4 coffee cups. MAOI combinations can seriously harm and kill you if handled quite recklessly. I found fewer limitations and hassles overall than some made it out to be for general life and food.
Vortioxetine is serotonergic and would not be taken with an MAOI, and has far fewer drug interactions.
Caffeine is extensively metabolized by cyp1a2, which luvox strongly inhibits. This means caffeine may last longer in your system / not be cleared as well if you were on luvox. If caffeine causes insomnia already then this might be exacerbated. I'm not sure 8 cups of coffee would be all that great on it in terms of lasting longer.
Coadministration of fluvoxamine impairs the clearance of caffeine and prolongs its elimination half-life, which is attributable to inhibition of CYP1A2 by fluvoxamine. The clinical importance of this interaction is not established. To evaluate the ...
www.ncbi.nlm.nih.gov
Well, AlphaMethylPhenyl has a strong point. Polysubstance use may not be tenable when you are trying to work on your issues. Treating substance side effects with other substances usually isn't the safest path. I'm not personally the biggest fan of 'self-medication' or similar terms, as I have seen many people justify very self-destructive patterns that don't seem to be beneficial and are counter to what they want, while proclaiming that they don't abuse substances and are just treating themselves because 'mental health hasn't caught up'. Granted, mental health certainly isn't there yet, and people aren't getting the care they need, but I am skeptical of not checking in and getting an outside perspective on mental health if the mental problems are significant enough that they lead to such misuse. Again there are definitely people missed by many systems and other benefits not listed, but I have a bit of skepticism and hope to give empathy.
I have seen some people turn around incredible self-destruction- I know it can be hard when we get in our own ways against what we want in the long term because of patterns of thinking and certain cycles of behavior. We can work to make change and break the cycles, even if it may take time or cause setbacks. Or at least something like that, not to sound too too positive.
Now as for coffee I use to say I liked 1-6 cups a day. Average 2-4. Sometimes just a small cup in the morning, sometimes 2 cups with a mid-morning fill, an espresso or double, and so on. I enjoy the taste (or have convinced myself that I do) and dislike caffeine pills and such. Affogato is a great dessert and mocha is my jam. My family drinks coffee quite extensively, my mom used to do 10-12 cups a day. I've done decaf from time to time, and given it up multiple times. On an oolong tea kick midday lately. Never had much of a problem with giving it up, besides a headache for a few days, but I seem to be that way with a lot of substances. Not quite a helpful paragraph in terms of giving up coffee but I encourage people to always try.
Ok, couple more questions/points on the bolded parts:
1st) I thought you said you were currently right now on BOTH Vortioxetine AND Parnate (and Parnate is an MAOI right??) and then you said "
Vortioxetine is serotonergic and should not be taken with an MAOI", so I'm confused, which one are you currently on if they can't be mixed together?
2) If you are NOT currently on both,
which of the two did you start on first, and which was the one which first seemed to help with the eye aversion problem?
3) If you are now only on one, then why did you choose to get off the other?
4) I don't mean to try to pin you in a corner, cause I know you said you "can't fully attribute the help with the eye contact aversion with either med" but
if you had to guess which one you think helped more with that PARTICULAR problem, which would it be?
5 So you are saying you do NOT think that caffeine or stimulants makes your eye contact aversion worse
6 have you gotten drunk while taking vortioxetine and if so, did you have a negative interactions
7 And yes, I fully agree with what AlphamethylPhenyl said, cause honestly, it's possible to be on any med or therapy regime and still not get well if you just fuck yourself up too much, and I FULLY realize that my best chances of feeling my best would involve being as close to straight edge as possible NOT including prescribed meds.
Whether or not I CAN DO THAT...or do it in the near future, is the question.
Obviously I have mentioned I have a lot of self control issues with substances as all addicts do, and my question was relating to which of the substances I mentioned I have a predisposition to use would be TRULY DANGEROUS to take on these meds.
I did not suggest I would be unwilling to even attempt to stop taking any of the drugs I like if I found a good med that helps me, and there are some I truly believe I could stop or would stand a very good chance at stopping, even permanently if I got on a helpful med, but there are others, mainly alcohol and caffeine, which if they had REALLY dangerous interactions with, or even something like Luvox which makes caffeine last longer, since I don't see myself being able to quit coffee now, which would simply not be smart for me to take seeing as I doubt my self control.
I believe if I found the right med I could give up Dex/Adderall (I'm already trying to quit), Kratom (also trying to quit/moderate), Phenibut/F-Phenibut (only use them like once a month or LESS anyway), shrooms, etc if I found the right med.
It's really booze and caffeine where if I find out mixing a med with them is dangerous or will just produce more problems in my life where IF POSSIBLE I will want to find an equally effective med that I can take somewhat safely if I should drink alcohol or coffee, because I don't yet trust myself to abstain from them completely.
I mean, my caffeine addiction is not something I feel I could quit right now (even though I want to) and I am just too prone to drinking for it to be safe for me to be on a med that is really dangerous to ever drink on.
I think most doctors would agree with what I'm saying, that if I really don't think I see myself standing a good chance at never drinking alcohol or coffee on something that would be REALLY DANGEROUS to combine with it, then I should NOT be prescribed that medication.
I mean, if you are mentally addicted to sports with intense head injury risk and you know you won't be able to stop yourself from partaking in those activities, should you be on a regime of a blood thinner which is highly likely to cause intense brain bleeding that cannot be stopped if you hit your head while on it??
Probably not.
Obviously my feeling that I am unable to yet completely say I will never have a drink of alcohol or coffee or ANYTHING that could EVER negatively interact with a med again must mean I am not as committed as someone else who would....but
more likely I'd say I just think I have less self control than that person and hence, it would be dangerous.
So neither an MAOI or Luvox sounds like a good choice at the moment for me.
Vortioxetine sounds interesting, and I've already been on 2 SSRIS (Prozac and lexapro, without bad interactions, so i could probably feel safe with that.
i mean, this is a harm reduction forum afterall, and if one doesnt trust oneself to safely avoid certain substances while on certain meds, than one must make the safe choice.
But i fully agree with what he said at least.
